PMID- 29276930 OWN - NLM STAT- MEDLINE DCOM- 20190516 LR - 20191113 IS - 0022-9040 (Print) IS - 0022-9040 (Linking) VI - 57 IP - 10 DP - 2017 Oct TI - [Perfusion-Metabolic Myocardial Scintigraphy in Prognosis of Left Ventricular Remodeling After Complex Surgical Treatment of Ischemic Cardiomyopathy]. PG - 56-64 AB - PURPOSE: To study capabilities of perfusion-metabolic myocardial scintigraphy for prediction of the left ventricular (LV) reverse remodeling after comprehensive surgical treatment of ischemic cardiomyopathy (ICMP). METHODS: The study included ICMP patients aged 56+/-7 years (n=32) who underwent surgical correction of LV dysfunction (myocardial revascularization, LV reconstruction, and mitral valve restoration). Inclusion criteria were significant coronary artery disease; myocardial infarction; New York Heart Association (NYHA) class III-IV heart failure; LV ejection fraction (EF) 60 mL/m2; and LV akinesia or dyskinesia according to echocardiography. Before surgery all patients were subjected to scintigraphy with 99mTc-MIBI (to assess perfusion) and with 123I-BMIPP (to assess myocardial metabolism). Scintigraphy results were expressed as median and lower; upper quartile (Me [lQ; hQ]). The clinical status and ventricular volume indicators were evaluated before surgery, in the early post-operative period (up to 4 weeks), and in the late post-operative period (12 months). RESULTS: At 12 months after intervention patients were divided into two groups: group 1 comprised patients (n=18) with beneficial outcome of the operation that stopped LV remodeling (ESI decreased, remained unchanged, or increased by. FAU - Lishmanov, Y B AU - Lishmanov YB AD - Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences. FAU - Gulya, M O AU - Gulya MO AD - Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences. FAU - Zavadovsky, K V AU - Zavadovsky KV AD - Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences. FAU - Andreev, S L AU - Andreev SL AD - Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences. FAU - Alexandrova, E A AU - Alexandrova EA AD - Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences. LA - rus PT - Journal Article PL - Russia (Federation) TA - Kardiologiia JT - Kardiologiia JID - 0376351 SB - IM MH - *Cardiomyopathies/diagnostic imaging MH - Humans MH - Middle Aged MH - *Myocardial Ischemia/diagnostic imaging MH - *Myocardial Perfusion Imaging MH - Prognosis MH - Stroke Volume MH - Treatment Outcome MH - *Ventricular Dysfunction, Left MH - Ventricular Remodeling OTO - NOTNLM OT - ischemic cardiomyopathy OT - myocardial scintigraphy OT - reverse remodeling OT - surgical ventricular restoration EDAT- 2017/12/26 06:00 MHDA- 2019/05/17 06:00 CRDT- 2017/12/26 06:00 PHST- 2017/12/26 06:00 [entrez] PHST- 2017/12/26 06:00 [pubmed] PHST- 2019/05/17 06:00 [medline] AID - 10.18087/cardio.2017.10.10032 [doi] PST - ppublish SO - Kardiologiia. 2017 Oct;57(10):56-64. doi: 10.18087/cardio.2017.10.10032.