PMID- 29279799
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220311
IS  - 2229-5097 (Print)
IS  - 2152-7806 (Electronic)
IS  - 2152-7806 (Linking)
VI  - 8
DP  - 2017
TI  - Prediction of 30-day mortality in spontaneous cerebellar hemorrhage.
PG  - 282
LID - 10.4103/sni.sni_479_16 [doi]
LID - 282
AB  - BACKGROUND: Cerebellar hemorrhage is a potentially life-threatening condition and 
      an understanding of the factors influencing outcome is essential for sound 
      clinical decision-making. METHODS: We retrospectively evaluated data from 50 
      consecutive patients who suffered a first spontaneous cerebellar hemorrhage (SCH) 
      from 2005 to 2014, analysing their short-term outcomes and identifying possible 
      clinical, radiological and therapeutic risk factors for poor prognosis and death 
      within 30 days. RESULTS: Among 50 patients with first SCH, the mean age was 72 +/- 
      10 years. Median Glasgow Coma Scale (GCS) score on admission was 11 
      [interquartile range (IQR) = 7-11]. Among 50 patients, 19 patients (38%) 
      underwent surgical hemorrhage evacuation with placement of an external 
      ventricular drain (EVD), 12 patients (24%) received an EVD only and 19 patients 
      (38%) were treated conservatively. The 30-day mortality rate was 36%. In 
      multivariate analysis only the GCS score on admission was a significant predictor 
      of 30-day mortality [odds ratio (OR) = 0.598; 95% confidence interval (CI) = 
      0.406-0.879; P = 0.009]. For prediction of 30-day mortality, receiver operating 
      characteristic curve analysis confirmed that the best cut-off point was a GCS 
      score of 10 on admission [area under the curve: 0.882, 95% CI = 0.717-1, P < 
      0.001]. CONCLUSION: Lower GCS score on admission was associated with increased 
      30-day mortality and poorer short-term outcome in patients with SCH. For patients 
      with a GCS score <10 on admission, it is important to balance the possibility of 
      survival afforded by further therapy against the formidable risk of significant 
      functional disability and poor quality of life.
FAU - Al Safatli, Diaa
AU  - Al Safatli D
AD  - Department of Neurosurgery, Jena University Hospital, Friedrich Schiller 
      University Jena, Germany.
FAU - Guenther, Albrecht
AU  - Guenther A
AD  - Department of Neurology, Jena University Hospital, Friedrich Schiller University 
      Jena, Germany.
FAU - McLean, Aaron Lawson
AU  - McLean AL
AD  - Department of Neurosurgery, Jena University Hospital, Friedrich Schiller 
      University Jena, Germany.
FAU - Waschke, Albrecht
AU  - Waschke A
AD  - Department of Neurosurgery, Jena University Hospital, Friedrich Schiller 
      University Jena, Germany.
FAU - Kalff, Rolf
AU  - Kalff R
AD  - Department of Neurosurgery, Jena University Hospital, Friedrich Schiller 
      University Jena, Germany.
FAU - Ewald, Christian
AU  - Ewald C
AD  - Department of Neurosurgery, Jena University Hospital, Friedrich Schiller 
      University Jena, Germany.
LA  - eng
PT  - Journal Article
DEP - 20171120
PL  - United States
TA  - Surg Neurol Int
JT  - Surgical neurology international
JID - 101535836
PMC - PMC5705929
OTO - NOTNLM
OT  - 30-day mortality
OT  - cerebellar hemorrhage
OT  - prognosis
OT  - risk factors
COIS- There are no conflicts of interest.
EDAT- 2017/12/28 06:00
MHDA- 2017/12/28 06:01
PMCR- 2017/11/20
CRDT- 2017/12/28 06:00
PHST- 2016/12/14 00:00 [received]
PHST- 2017/05/30 00:00 [accepted]
PHST- 2017/12/28 06:00 [entrez]
PHST- 2017/12/28 06:00 [pubmed]
PHST- 2017/12/28 06:01 [medline]
PHST- 2017/11/20 00:00 [pmc-release]
AID - SNI-8-282 [pii]
AID - 10.4103/sni.sni_479_16 [doi]
PST - epublish
SO  - Surg Neurol Int. 2017 Nov 20;8:282. doi: 10.4103/sni.sni_479_16. eCollection 
      2017.