PMID- 29280489
OWN - NLM
STAT- MEDLINE
DCOM- 20190131
LR  - 20190131
IS  - 1531-4995 (Electronic)
IS  - 0023-852X (Linking)
VI  - 128
IP  - 8
DP  - 2018 Aug
TI  - Down syndrome and pediatric obstructive sleep apnea surgery: A national cohort.
PG  - 1963-1969
LID - 10.1002/lary.27063 [doi]
AB  - OBJECTIVES/HYPOTHESIS: To analyze the trend of sleep surgeries in pediatric 
      patients with Down syndrome (DS) and obstructive sleep apnea (OSA), and to 
      compare this to nonsyndromic (NS) children with OSA. STUDY DESIGN: Retrospective 
      cohort database analysis. METHODS: Analysis of the 1997 to 2012 editions of the 
      Kid's Inpatient Database was conducted. Using International Classification of 
      Diseases, Ninth Revision codes, all patients with OSA were identified, and 
      subsequently, subgroups of NS children and children with DS were identified. 
      Trends of the number and types of sleep surgeries were analyzed. RESULTS: A total 
      of 48,301 and 2,991 sleep surgeries were identified in the NS and DS groups, 
      respectively, during the study period. Tonsillectomy with adenoidectomy was the 
      most common procedure in both groups, but the proportion of tonsillectomy with 
      adenoidectomy decreased over time (P < .01). The proportion of palatal surgery 
      and tracheostomy also decreased significantly, whereas there was an increase in 
      the proportion of lingual tonsillectomies, tongue-base reduction procedures, and 
      supraglottoplasties performed in both groups over time. The relative rates of 
      change in these procedures were higher in the DS population. CONCLUSIONS: 
      Tonsillectomy with adenoidectomy remains the most commonly performed procedure, 
      although there was a significant increase in other sleep surgeries performed 
      (lingual tonsillectomy, tongue-base reduction, and supraglottoplasty) between the 
      two study periods, especially in children with DS. LEVEL OF EVIDENCE: 2c. 
      Laryngoscope, 1963-1969, 2018.
CI  - (c) 2017 The American Laryngological, Rhinological and Otological Society, Inc.
FAU - Ong, Adrian A
AU  - Ong AA
AUID- ORCID: 0000-0001-5822-833X
AD  - Department of Otolaryngology, University at Buffalo Jacobs School of Medicine and 
      Biomedical Sciences, Buffalo, New York.
FAU - Atwood, Carlyn M
AU  - Atwood CM
AD  - Department of Otolaryngology-Head and Neck Surgery, Medical University of South 
      Carolina, Charleston, South Carolina, U.S.A.
FAU - Nguyen, Shaun A
AU  - Nguyen SA
AUID- ORCID: 0000-0003-0664-4571
AD  - Department of Otolaryngology-Head and Neck Surgery, Medical University of South 
      Carolina, Charleston, South Carolina, U.S.A.
FAU - Teufel, Ronald J 2nd
AU  - Teufel RJ 2nd
AD  - Department of Pediatrics, Medical University of South Carolina, Charleston, South 
      Carolina, U.S.A.
FAU - Lal, Chitra
AU  - Lal C
AD  - Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical 
      University of South Carolina, Charleston, South Carolina, U.S.A.
FAU - LaRosa, Angela C
AU  - LaRosa AC
AD  - Department of Pediatrics, Medical University of South Carolina, Charleston, South 
      Carolina, U.S.A.
FAU - White, David R
AU  - White DR
AD  - Department of Otolaryngology-Head and Neck Surgery, Medical University of South 
      Carolina, Charleston, South Carolina, U.S.A.
LA  - eng
PT  - Journal Article
DEP - 20171227
PL  - United States
TA  - Laryngoscope
JT  - The Laryngoscope
JID - 8607378
SB  - IM
MH  - Adenoidectomy
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Down Syndrome/*complications
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Palate/surgery
MH  - Retrospective Studies
MH  - Sleep Apnea, Obstructive/*etiology/*surgery
MH  - Tongue/surgery
MH  - Tonsillectomy
MH  - Tracheostomy
MH  - Young Adult
OTO - NOTNLM
OT  - Down syndrome
OT  - Kids' Inpatient Database
OT  - Pediatric
OT  - obstructive sleep apnea
OT  - sleep procedures
OT  - sleep-disordered breathing
OT  - surgical trends
EDAT- 2017/12/28 06:00
MHDA- 2019/02/01 06:00
CRDT- 2017/12/28 06:00
PHST- 2017/05/24 00:00 [received]
PHST- 2017/10/12 00:00 [revised]
PHST- 2017/11/22 00:00 [accepted]
PHST- 2017/12/28 06:00 [pubmed]
PHST- 2019/02/01 06:00 [medline]
PHST- 2017/12/28 06:00 [entrez]
AID - 10.1002/lary.27063 [doi]
PST - ppublish
SO  - Laryngoscope. 2018 Aug;128(8):1963-1969. doi: 10.1002/lary.27063. Epub 2017 Dec 
      27.