PMID- 29282408
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220311
IS  - 1664-5464 (Print)
IS  - 1664-5464 (Electronic)
IS  - 1664-5464 (Linking)
VI  - 7
IP  - 3
DP  - 2017 Sep-Dec
TI  - Behavioural and Psychological Symptoms of Dementia: Correlates and Impact on 
      Caregiver Distress.
PG  - 354-365
LID - 10.1159/000481568 [doi]
AB  - AIMS: To evaluate the behavioural and psychological symptoms of dementia (BPSD), 
      to determine their correlation with types and stages of dementia and patient 
      demographics, and to assess the impact on caregiver distress. METHODS: This 
      cross-sectional study recruited consecutive dementia patients and caregivers who 
      attended our cognitive clinic. Standard criteria were used to classify types of 
      dementia. BPSD were assessed with the Neuropsychiatric Inventory, and its 
      distress scale was used for caregiver distress. RESULTS: Of a total 107 patients, 
      nearly all (99.1%) had at least one BPSD; 71% had >/=4 symptoms. Most frequent were 
      apathy and agitation, followed by irritability, sleep and appetite disorders, and 
      mood disorders; disinhibition and euphoria were least frequent. BPSD were less 
      prominent with increasing age; males showed more agitation. Apathy and eating 
      disorders were more prevalent in the rural community. BPSD were highest in 
      frontotemporal dementia (FTD), followed by dementia with Lewy bodies (DLB), and 
      least in vascular dementia. Hallucinations were more common in DLB, aberrant 
      motor behaviour in FTD. All domains of BPSD, except for anxiety and euphoria, 
      were more prominent with increasing severity of dementia. Increasing BPSD (except 
      for euphoria) caused higher caregiver distress. CONCLUSION: BPSD are universally 
      present, bear correlates with dementia type and severity, and cause significant 
      caregiver distress.
FAU - Mukherjee, Adreesh
AU  - Mukherjee A
AD  - Department of Neurology, Bangur Institute of Neurosciences and Institute of 
      Postgraduate Medical Education and Research (IPGME&R), Kolkata, India.
FAU - Biswas, Atanu
AU  - Biswas A
AD  - Department of Neurology, Bangur Institute of Neurosciences and Institute of 
      Postgraduate Medical Education and Research (IPGME&R), Kolkata, India.
FAU - Roy, Arijit
AU  - Roy A
AD  - Department of Neurology, Bankura Sammilani Medical College, Bankura, India.
FAU - Biswas, Samar
AU  - Biswas S
AD  - Department of Neurology, Bangur Institute of Neurosciences and Institute of 
      Postgraduate Medical Education and Research (IPGME&R), Kolkata, India.
FAU - Gangopadhyay, Goutam
AU  - Gangopadhyay G
AD  - Department of Neurology, Bangur Institute of Neurosciences and Institute of 
      Postgraduate Medical Education and Research (IPGME&R), Kolkata, India.
FAU - Das, Shyamal Kumar
AU  - Das SK
AD  - Department of Neurology, Bangur Institute of Neurosciences and Institute of 
      Postgraduate Medical Education and Research (IPGME&R), Kolkata, India.
LA  - eng
PT  - Journal Article
DEP - 20171101
PL  - Switzerland
TA  - Dement Geriatr Cogn Dis Extra
JT  - Dementia and geriatric cognitive disorders extra
JID - 101564825
PMC - PMC5731149
OTO - NOTNLM
OT  - Behavioural and psychological symptoms of dementia
OT  - Caregiver distress
OT  - Clinical Dementia Rating scale
OT  - Neuropsychiatric Inventory
EDAT- 2017/12/29 06:00
MHDA- 2017/12/29 06:01
PMCR- 2017/11/01
CRDT- 2017/12/29 06:00
PHST- 2017/07/24 00:00 [received]
PHST- 2017/09/17 00:00 [accepted]
PHST- 2017/12/29 06:00 [entrez]
PHST- 2017/12/29 06:00 [pubmed]
PHST- 2017/12/29 06:01 [medline]
PHST- 2017/11/01 00:00 [pmc-release]
AID - dee-0007-0354 [pii]
AID - 10.1159/000481568 [doi]
PST - epublish
SO  - Dement Geriatr Cogn Dis Extra. 2017 Nov 1;7(3):354-365. doi: 10.1159/000481568. 
      eCollection 2017 Sep-Dec.