PMID- 29299044 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1745-0179 (Print) IS - 1745-0179 (Electronic) IS - 1745-0179 (Linking) VI - 13 DP - 2017 TI - Relationship Between Brain-Derived Neurotrofic Factor (Bdnf) and Sleep on Depression: A Critical Review. PG - 213-219 LID - 10.2174/1745017901713010213 [doi] AB - The Brain-Derived Neurotrofic Factor (BDNF) is one of the most important neurotrophins in the brain and it is suggested influences the activity of the serotonergic, noradrenergic and dopaminergic pathways. In the last few years, it has been hypothesized that BDNF level is related with depression and sleep. Several studies show that depressive subjects present low levels of BDNF in the brain. Poor sleep quality is also related with alterations in the BDNF concentration. Some authors argue that most of the cases show that impaired sleep quality increases the stress and, consequently, the vulnerability to depressive disorders, suggesting that there is a relationship between sleep, depression and BDNF levels. FAU - Monteiro, Barbara C AU - Monteiro BC AD - Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. FAU - Monteiro, Suzana AU - Monteiro S AD - Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. FAU - Candida, Maristela AU - Candida M AD - Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. FAU - Adler, Nathalia AU - Adler N AD - Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. FAU - Paes, Flavia AU - Paes F AD - Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. FAU - Rocha, Nuno AU - Rocha N AD - Polytechnic Institute of Porto, Health School, , Portugal. AD - Intercontinental Neuroscience Research Group, Brazil. FAU - Nardi, Antonio Egidio AU - Nardi AE AD - Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. FAU - Murillo-Rodriguez, Eric AU - Murillo-Rodriguez E AD - Laboratorio de Neurociencias Moleculares e Integrativas, Escuela de Medicina, Division Ciencias de la Salud, Universidad Anahuac Mayab, Merida, Mexico. AD - Intercontinental Neuroscience Research Group, Brazil. FAU - Machado, Sergio AU - Machado S AD - Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. AD - Intercontinental Neuroscience Research Group, Brazil. AD - Physical Activity Neuroscience Laboratory (LABNAF), Physical Activity Sciences Post-Graduate Program, Salgado de Oliveira University (UNIVERSO), , Brazil. LA - eng PT - Journal Article DEP - 20171121 PL - United Arab Emirates TA - Clin Pract Epidemiol Ment Health JT - Clinical practice and epidemiology in mental health : CP & EMH JID - 101245735 PMC - PMC5725585 OTO - NOTNLM OT - Antidepressants OT - BDNF OT - BDNF studies OT - Depression OT - Sleep OT - Sleep quality EDAT- 2018/01/05 06:00 MHDA- 2018/01/05 06:01 PMCR- 2017/11/21 CRDT- 2018/01/05 06:00 PHST- 2017/06/08 00:00 [received] PHST- 2017/10/11 00:00 [revised] PHST- 2017/10/22 00:00 [accepted] PHST- 2018/01/05 06:00 [entrez] PHST- 2018/01/05 06:00 [pubmed] PHST- 2018/01/05 06:01 [medline] PHST- 2017/11/21 00:00 [pmc-release] AID - CPEMH-13-213 [pii] AID - 10.2174/1745017901713010213 [doi] PST - epublish SO - Clin Pract Epidemiol Ment Health. 2017 Nov 21;13:213-219. doi: 10.2174/1745017901713010213. eCollection 2017.