PMID- 29303059
OWN - NLM
STAT- MEDLINE
DCOM- 20181115
LR  - 20181202
IS  - 1933-7205 (Electronic)
IS  - 1933-7191 (Linking)
VI  - 25
IP  - 3
DP  - 2018 Mar
TI  - Association Between Endometriosis and Preterm Birth in Women With Spontaneous 
      Conception or Using Assisted Reproductive Technology: A Systematic Review and 
      Meta-Analysis of Cohort Studies.
PG  - 311-319
LID - 10.1177/1933719117749760 [doi]
AB  - OBJECTIVE: To perform a systematic review and meta-analysis to estimate the 
      effect of endometriosis on preterm birth (PB) risk. METHODS: Searches were 
      conducted in PubMed-MEDLINE, Embase, Scopus, Web of Science, Cochrane Library, 
      Google Scholar, and SciELO for studies published in all languages from inception 
      through April 2017. We included cohort studies evaluating pregnant women with and 
      without endometriosis and conception either by spontaneous conception (SC) or 
      with assisted reproductive technology (ART). Primary outcome was PB (<37 weeks), 
      and secondary outcomes were intrauterine growth restriction (IUGR), low 
      birthweight, small for gestational age (SGA), and birthweight. Pooled odds ratios 
      (ORs) and its 95% confidence interval (CI) were calculated as effects, and 
      random-effects models were used for meta-analyses. Risk of bias was assessed with 
      the Newcastle-Ottawa Scale, and heterogeneity of effects among studies was 
      described with the I(2) statistic. RESULTS: We identified 9 cohort studies 
      including a total of 1 496 715 pregnancies (13 798 with endometriosis diagnosis). 
      In women with endometriosis, the PB risk was significantly increased in both SC 
      (OR: 1.59; 95% CI: 1.32-1.90) and ART (OR: 1.43; 95% CI: 1.14-1.79). The SGA risk 
      was increased in women with endometriosis (OR: 1.16; 95% CI: 1.05-1.28), while 
      the IUGR and low birthweight risks and birthweight were not affected by 
      endometriosis. CONCLUSION: Endometriosis is associated with increased PB risk in 
      both SC and women who obtained pregnancy using ART. Prospective studies 
      evaluating relevant outcomes are needed to confirm these results.
FAU - Perez-Lopez, Faustino R
AU  - Perez-Lopez FR
AD  - 1 Facultad de Medicina, Universidad de Zaragoza, Red de Investigacion en 
      Ginecologia, Obstetricia y Reproduccion, Instituto Aragones de Ciencias de la 
      Salud (IACS), Zaragoza, Spain.
AD  - 2 Department of Obstetrics and Gynecology, Lozano Blesa University Hospital, 
      Zaragoza, Spain.
FAU - Villagrasa-Boli, Pablo
AU  - Villagrasa-Boli P
AD  - 1 Facultad de Medicina, Universidad de Zaragoza, Red de Investigacion en 
      Ginecologia, Obstetricia y Reproduccion, Instituto Aragones de Ciencias de la 
      Salud (IACS), Zaragoza, Spain.
FAU - Munoz-Olarte, Maria
AU  - Munoz-Olarte M
AD  - 1 Facultad de Medicina, Universidad de Zaragoza, Red de Investigacion en 
      Ginecologia, Obstetricia y Reproduccion, Instituto Aragones de Ciencias de la 
      Salud (IACS), Zaragoza, Spain.
FAU - Morera-Grau, Alex
AU  - Morera-Grau A
AD  - 1 Facultad de Medicina, Universidad de Zaragoza, Red de Investigacion en 
      Ginecologia, Obstetricia y Reproduccion, Instituto Aragones de Ciencias de la 
      Salud (IACS), Zaragoza, Spain.
FAU - Cruz-Andres, Pablo
AU  - Cruz-Andres P
AD  - 1 Facultad de Medicina, Universidad de Zaragoza, Red de Investigacion en 
      Ginecologia, Obstetricia y Reproduccion, Instituto Aragones de Ciencias de la 
      Salud (IACS), Zaragoza, Spain.
FAU - Hernandez, Adrian V
AU  - Hernandez AV
AD  - 3 School of Medicine, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, 
      Peru.
AD  - 4 Hartford Hospital Evidence-based Practice Center, University of Connecticut, 
      Hartford, CT, USA.
CN  - Health Outcomes and Systematic Analyses (HOUSSAY) Project
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20180105
PL  - United States
TA  - Reprod Sci
JT  - Reproductive sciences (Thousand Oaks, Calif.)
JID - 101291249
SB  - IM
MH  - Endometriosis/*complications
MH  - Female
MH  - Fetal Growth Retardation/*etiology
MH  - Humans
MH  - Infant, Newborn
MH  - Infant, Small for Gestational Age
MH  - Pregnancy
MH  - *Pregnancy Outcome
MH  - Premature Birth/*etiology
MH  - *Reproductive Techniques, Assisted
OTO - NOTNLM
OT  - assisted reproductive technology
OT  - birthweight
OT  - endometriosis
OT  - infertility
OT  - meta-analysis
OT  - preterm birth
OT  - small for gestational age
OT  - spontaneous conception
EDAT- 2018/01/06 06:00
MHDA- 2018/11/16 06:00
CRDT- 2018/01/06 06:00
PHST- 2018/01/06 06:00 [pubmed]
PHST- 2018/11/16 06:00 [medline]
PHST- 2018/01/06 06:00 [entrez]
AID - 10.1177/1933719117749760 [doi]
PST - ppublish
SO  - Reprod Sci. 2018 Mar;25(3):311-319. doi: 10.1177/1933719117749760. Epub 2018 Jan 
      5.