PMID- 29304014 OWN - NLM STAT- MEDLINE DCOM- 20181112 LR - 20190318 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 15 IP - 1 DP - 2018 Jan 5 TI - Environmental Risk Factors for Developing Type 2 Diabetes Mellitus: A Systematic Review. LID - 10.3390/ijerph15010078 [doi] LID - 78 AB - Different elements of the environment have been posited to influence type 2 diabetes mellitus (T2DM). This systematic review summarizes evidence on the environmental determinants of T2DM identified in four databases. It proposes a theoretical framework illustrating the link between environment and T2DM, and briefly discusses some methodological challenges and potential solutions, and opportunities for future research. Walkability, air pollution, food and physical activity environment and roadways proximity were the most common environmental characteristics studied. Of the more than 200 reported and extracted relationships assessed in 60 studies, 82 showed significant association in the expected direction. In general, higher levels of walkability and green space were associated with lower T2DM risk, while increased levels of noise and air pollution were associated with greater risk. Current evidence is limited in terms of volume and study quality prohibiting causal inferences. However, the evidence suggests that environmental characteristics may influence T2DM prevention, and also provides a reasonable basis for further investigation with better quality data and longitudinal studies with policy-relevant environmental measures. This pursuit of better evidence is critical to support health-orientated urban design and city planning. FAU - Dendup, Tashi AU - Dendup T AD - Population Wellbeing and Environment Research Lab (PowerLab), School of Health and Society, Faculty of Social Sciences, University of Wollongong, Wollongong, NSW 2522, Australia. td869@uowmail.edu.au. FAU - Feng, Xiaoqi AU - Feng X AD - Population Wellbeing and Environment Research Lab (PowerLab), School of Health and Society, Faculty of Social Sciences, University of Wollongong, Wollongong, NSW 2522, Australia. xfeng@uow.edu.au. AD - Menzies Centre for Health Policy, University of Sydney, Sydney, NSW 2006, Australia. xfeng@uow.edu.au. FAU - Clingan, Stephanie AU - Clingan S AD - Population Wellbeing and Environment Research Lab (PowerLab), School of Health and Society, Faculty of Social Sciences, University of Wollongong, Wollongong, NSW 2522, Australia. stc51@uowmail.edu.au. FAU - Astell-Burt, Thomas AU - Astell-Burt T AD - Population Wellbeing and Environment Research Lab (PowerLab), School of Health and Society, Faculty of Social Sciences, University of Wollongong, Wollongong, NSW 2522, Australia. thomasab@uow.edu.au. AD - Menzies Centre for Health Policy, University of Sydney, Sydney, NSW 2006, Australia. thomasab@uow.edu.au. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PT - Systematic Review DEP - 20180105 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - Air Pollution/*adverse effects MH - *City Planning MH - Diabetes Mellitus, Type 2/*etiology/physiopathology MH - Environment Design/*statistics & numerical data MH - Environmental Exposure/*adverse effects MH - Exercise MH - Female MH - Humans MH - Residence Characteristics MH - Risk Factors MH - *Urban Health MH - Walking PMC - PMC5800177 OTO - NOTNLM OT - *air pollution OT - *environment OT - *green space OT - *noise OT - *type 2 diabetes mellitus OT - *walkability COIS- The authors declare no conflict of interest. EDAT- 2018/01/06 06:00 MHDA- 2018/11/13 06:00 PMCR- 2018/01/01 CRDT- 2018/01/06 06:00 PHST- 2017/11/29 00:00 [received] PHST- 2017/12/19 00:00 [revised] PHST- 2017/12/23 00:00 [accepted] PHST- 2018/01/06 06:00 [entrez] PHST- 2018/01/06 06:00 [pubmed] PHST- 2018/11/13 06:00 [medline] PHST- 2018/01/01 00:00 [pmc-release] AID - ijerph15010078 [pii] AID - ijerph-15-00078 [pii] AID - 10.3390/ijerph15010078 [doi] PST - epublish SO - Int J Environ Res Public Health. 2018 Jan 5;15(1):78. doi: 10.3390/ijerph15010078.