PMID- 29304261
OWN - NLM
STAT- MEDLINE
DCOM- 20190311
LR  - 20190311
IS  - 2325-8179 (Electronic)
IS  - 2325-8160 (Linking)
VI  - 49
IP  - 1
DP  - 2018 Jan 1
TI  - An Evaluation of the Relationship Between Clinically Unilateral Pseudoexfoliation 
      Syndrome and Age-Related Macular Degeneration.
PG  - 12-19
LID - 10.3928/23258160-20171215-02 [doi]
AB  - BACKGROUND AND OBJECTIVE: To evaluate the relationship between age-related 
      macular degeneration (AMD) and clinically unilateral pseudoexfoliation syndrome 
      (XFS). PATIENTS AND METHODS: Seventy-six patients (152 eyes) with bilateral AMD 
      and clinically unilateral XFS were included. Eyes with AMD were divided into 
      three stages (early, intermediate, and late), based on the Beckman Initiative for 
      Macular Research Classification Committee of fundus findings. The distribution of 
      AMD lesions was assessed in both groups, and the subfoveal choroidal thickness 
      (SFCT) was measured using enhanced depth imaging spectral-domain optical 
      coherence tomography (SD-OCT). RESULTS: There were significantly more early and 
      intermediate-stage AMD cases in eyes with XFS than in non-XFS fellow eyes (P < 
      .05). In contrast, there were significantly fewer wet AMD cases in XFS eyes than 
      in non-XFS fellow eyes (P < .05). SFCT in all AMD stages was significantly lower 
      in eyes with XFS (P < .05). CONCLUSION: XFS was associated with a lower 
      prevalence of wet AMD. Further studies are required to elucidate this 
      association. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:12-19.].
CI  - Copyright 2018, SLACK Incorporated.
FAU - Zengin, Mehmet Ozgur
AU  - Zengin MO
FAU - Karti, Omer
AU  - Karti O
FAU - Karahan, Eyyup
AU  - Karahan E
FAU - Kusbeci, Tuncay
AU  - Kusbeci T
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Ophthalmic Surg Lasers Imaging Retina
JT  - Ophthalmic surgery, lasers & imaging retina
JID - 101599215
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Choroid/*pathology
MH  - Cross-Sectional Studies
MH  - Disease Progression
MH  - Exfoliation Syndrome/*complications/diagnosis
MH  - Female
MH  - Fluorescein Angiography/*methods
MH  - Follow-Up Studies
MH  - Fundus Oculi
MH  - Humans
MH  - Macula Lutea/*pathology
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/*methods
MH  - *Visual Acuity
MH  - Wet Macular Degeneration/diagnosis/*etiology
EDAT- 2018/01/06 06:00
MHDA- 2019/03/12 06:00
CRDT- 2018/01/06 06:00
PHST- 2017/03/09 00:00 [received]
PHST- 2017/08/02 00:00 [accepted]
PHST- 2018/01/06 06:00 [entrez]
PHST- 2018/01/06 06:00 [pubmed]
PHST- 2019/03/12 06:00 [medline]
AID - 10.3928/23258160-20171215-02 [doi]
PST - ppublish
SO  - Ophthalmic Surg Lasers Imaging Retina. 2018 Jan 1;49(1):12-19. doi: 
      10.3928/23258160-20171215-02.