PMID- 29304270 OWN - NLM STAT- MEDLINE DCOM- 20190311 LR - 20190311 IS - 2325-8179 (Electronic) IS - 2325-8160 (Linking) VI - 49 IP - 1 DP - 2018 Jan 1 TI - A New OCT Finding in Purtscher-Like Retinopathy. PG - 64-69 LID - 10.3928/23258160-20171215-11 [doi] AB - The authors report a new spectral-domain optical coherence tomography (SD-OCT) appearance observed in two patients with Purtscher-like retinopathy. In this prospective case series of three eyes of two patients with Purtscher-like retinopathy, the patients were assessed with biomicroscopy, fluorescein angiography (FA), and SD-OCT. The last examinations of the patients were performed at 3 months and 12 months, respectively. Both patients presented with decreased visual acuity. Fundus examination revealed a whitish-appearing parafoveal retina and scattered cotton-wool spots in the posterior retina. FA showed hypofluorescent spots that correspond to the cotton-wool spots and retinal hemorrhages seen clinically. SD-OCT scan of cotton-wool spots showed focal hyperreflectivity in the nerve fiber and the ganglion cell layers. SD-OCT scan of the macula in both patients showed hyperreflective areas in the inner plexiform, inner nuclear, outer plexiform, and outer nuclear layers. Hyperreflective areas disappeared during follow-up of the patients. Retinal thinning was observed in these areas after resolution. These findings are in accordance with histopathological findings and support the microvascular embolization theory in pathophysiology of Purtscher-like retinopathy. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:64-69.]. CI - Copyright 2018, SLACK Incorporated. FAU - Yaylali, Sevil Ari AU - Yaylali SA FAU - Bromand, Nedim AU - Bromand N FAU - Kilic, Guler AU - Kilic G LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Ophthalmic Surg Lasers Imaging Retina JT - Ophthalmic surgery, lasers & imaging retina JID - 101599215 SB - IM MH - Adult MH - Fluorescein Angiography/methods MH - Fundus Oculi MH - Humans MH - Macula Lutea/*pathology MH - Male MH - Retinal Diseases/*diagnosis MH - Tomography, Optical Coherence/*methods MH - *Visual Acuity EDAT- 2018/01/06 06:00 MHDA- 2019/03/12 06:00 CRDT- 2018/01/06 06:00 PHST- 2017/04/06 00:00 [received] PHST- 2017/09/21 00:00 [accepted] PHST- 2018/01/06 06:00 [entrez] PHST- 2018/01/06 06:00 [pubmed] PHST- 2019/03/12 06:00 [medline] AID - 10.3928/23258160-20171215-11 [doi] PST - ppublish SO - Ophthalmic Surg Lasers Imaging Retina. 2018 Jan 1;49(1):64-69. doi: 10.3928/23258160-20171215-11.