PMID- 29305363
OWN - NLM
STAT- MEDLINE
DCOM- 20180808
LR  - 20240327
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 2018
DP  - 2018 Jan 5
TI  - Efficacy and safety of maintenance electroconvulsive therapy for sustaining 
      resolution of severe aggression in a major neurocognitive disorder.
LID - bcr-2017-222100 [pii]
LID - 10.1136/bcr-2017-222100 [doi]
LID - bcr2017222100
AB  - We report a novel electroconvulsive therapy (ECT) regimen for sustaining the 
      resolution of behavioural and psychological symptoms of dementia (BPSD) using 
      alternating acute and maintenance ECT (M-ECT) trials. A 64-year-old man 
      presenting with major neurocognitive disorder was admitted for acute behavioural 
      disturbances and physical aggression. With few treatment options, the impact on 
      patients' quality of life often supersedes cognitive symptoms and is a predictor 
      of long-term institutionalisation. Recent studies indicate that ECT may be an 
      effective and safe way to address BPSD. Clinicians have little information about 
      when and how to stop a successful course of acute ECT or the long-term advantages 
      of M-ECT with subsequent intermittent acute ECT. This case emphasises the benefit 
      of M-ECT and describes potential challenges associated with abrupt 
      discontinuation. This case is the first to detail tapering ECT for treatment of 
      aggression in dementia by interchanging acute and M-ECT courses in response to 
      symptom burden.
CI  - (c) BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 
      2018. All rights reserved. No commercial use is permitted unless otherwise 
      expressly granted.
FAU - Selvadurai, Melanie Isabella
AU  - Selvadurai MI
AD  - DeGroote School of Business, McMaster University, Burlington, Ontario, Canada.
AD  - Department of Psychiatry, Ontario Shores Centre for Mental Health Sciences, 
      University of Toronto, Whitby, Ontario, Canada.
FAU - Waxman, Robyn
AU  - Waxman R
AD  - Department of Psychiatry, Ontario Shores Centre for Mental Health Sciences, 
      University of Toronto, Whitby, Ontario, Canada.
FAU - Ghaffar, Omar
AU  - Ghaffar O
AD  - Department of Psychiatry, Ontario Shores Centre for Mental Health Sciences, 
      University of Toronto, Whitby, Ontario, Canada.
FAU - Fischler, Ilan
AU  - Fischler I
AD  - Department of Psychiatry, Ontario Shores Centre for Mental Health Sciences, 
      University of Toronto, Whitby, Ontario, Canada.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20180105
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
SB  - IM
MH  - Aggression/*psychology
MH  - Dementia/psychology/*therapy
MH  - Electroconvulsive Therapy/*methods
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Treatment Outcome
PMC - PMC5775786
OTO - NOTNLM
OT  - geriatric medicine
OT  - medical management
OT  - memory disorders (psychiatry)
COIS- Competing interests: None declared.
EDAT- 2018/01/07 06:00
MHDA- 2018/08/09 06:00
PMCR- 2018/01/05
CRDT- 2018/01/07 06:00
PHST- 2018/01/07 06:00 [entrez]
PHST- 2018/01/07 06:00 [pubmed]
PHST- 2018/08/09 06:00 [medline]
PHST- 2018/01/05 00:00 [pmc-release]
AID - bcr-2017-222100 [pii]
AID - 10.1136/bcr-2017-222100 [doi]
PST - epublish
SO  - BMJ Case Rep. 2018 Jan 5;2018:bcr2017222100. doi: 10.1136/bcr-2017-222100.