PMID- 29306672
OWN - NLM
STAT- Publisher
LR  - 20240227
IS  - 2531-0437 (Electronic)
IS  - 2531-0429 (Linking)
DP  - 2018 Jan 3
TI  - The Bronchiectasis Severity Index and FACED score for assessment of the severity 
      of bronchiectasis.
LID - S2173-5115(17)30154-9 [pii]
LID - 10.1016/j.rppnen.2017.08.009 [doi]
AB  - INTRODUCTION: Bronchiectasis (BC) is a multidimensional and etiologically diverse 
      disease and, therefore, no single parameter can be used to determine its overall 
      severity and prognosis. In this regard, two different validated scores are 
      currently used to assess the severity of non-cystic fibrosis bronchiectasis 
      (NCFB): the FACED score and the Bronchiectasis Severity Index (BSI). OBJECTIVE: 
      To describe the etiology of NCFB and compare the results of the assessment of 
      NCFB severity obtained via FACED and BSI scores. METHODS: Retrospective study of 
      demographic and clinical data of a convenience sample of NCFB patients attending 
      the Functional Breathing Re-adaptation appointment at the Pneumology B Unit, 
      University Hospital Center of Coimbra. All patients underwent evaluation of the 
      variables incorporated in the FACED score (FEV1% predicted, age, chronic 
      colonization by Pseudomonas aeruginosa, radiological extent of the disease, and 
      dyspnea) and in the BSI (age, body mass index, FEV1% predicted, hospitalization 
      and exacerbations before study, dyspnea, chronic colonization by P. aeruginosa 
      and other microrganisms, and radiological extent of the disease). Statistical 
      analysis of the data was performed using Microsoft Excel((R)) and IBM SPSS((R)) v23. 
      RESULTS: The sample included 40 patients, 22 females and 18 males, aged 39-87 
      years. Regarding the etiology of NCFB, we found: idiopathic (60%), 
      post-infectious (20%), sequelae of pulmonary tuberculosis (12.5%) and primary 
      immunodeficiency related (7.5%). According to the FACED score we found 20 
      patients (50%) with mild BC, 15 patients (37.5%) with moderate and 5 patients 
      (12.5%) with severe BC. The frequency of patients with low, intermediate and high 
      BSI was 13 (32.5%), 13 (32.5%) and 14 (35%), respectively in relation to derived 
      BSI, Moreover, we observed a weak but statistically significant association 
      between FACED and BSI scores: Fisher's exact test (p=0.004), tau-b de Kendall 
      (0.469; p=0.001). The Kappa test (0.330; p=0.002) also shows us that there is 55% 
      agreement between the two scales. CONCLUSION: There is a small but significant 
      correlation between the two scales: a tendency is observed for patients to be 
      classified with a higher BSI compared to the FACED score. This can be explained 
      by the fact that BSI (and not FACED) evaluates parameters including BMI, 
      hospitalization and exacerbations before study, chronic colonization by other 
      microorganisms and development of cystic bronchiectasis. Further studies should 
      address how these scores may impact clinical practice.
CI  - Copyright (c) 2017 Sociedade Portuguesa de Pneumologia. Published by Elsevier 
      Espana, S.L.U. All rights reserved.
FAU - Costa, J C
AU  - Costa JC
AD  - Pneumology B Unit, University Hospital Center of Coimbra, Coimbra, Portugal. 
      Electronic address: josecoutinhocosta99@gmail.com.
FAU - Machado, J N
AU  - Machado JN
AD  - Pneumology B Unit, University Hospital Center of Coimbra, Coimbra, Portugal.
FAU - Ferreira, C
AU  - Ferreira C
AD  - Pneumology B Unit, University Hospital Center of Coimbra, Coimbra, Portugal.
FAU - Gama, J
AU  - Gama J
AD  - Mathematics Department, University of Beira Interior, Covilha, Portugal.
FAU - Rodrigues, C
AU  - Rodrigues C
AD  - Pneumology B Unit, University Hospital Center of Coimbra, Coimbra, Portugal.
LA  - eng
PT  - Journal Article
DEP - 20180103
PL  - Spain
TA  - Pulmonology
JT  - Pulmonology
JID - 101723786
OTO - NOTNLM
OT  - BSI
OT  - FACED
OT  - Non-cystic fibrosis bronchiectasis
EDAT- 2018/01/08 06:00
MHDA- 2018/01/08 06:00
CRDT- 2018/01/08 06:00
PHST- 2017/03/14 00:00 [received]
PHST- 2017/08/17 00:00 [revised]
PHST- 2017/08/29 00:00 [accepted]
PHST- 2018/01/08 06:00 [pubmed]
PHST- 2018/01/08 06:00 [medline]
PHST- 2018/01/08 06:00 [entrez]
AID - S2173-5115(17)30154-9 [pii]
AID - 10.1016/j.rppnen.2017.08.009 [doi]
PST - aheadofprint
SO  - Pulmonology. 2018 Jan 3:S2173-5115(17)30154-9. doi: 10.1016/j.rppnen.2017.08.009.