PMID- 29308000 OWN - NLM STAT- MEDLINE DCOM- 20180808 LR - 20181113 IS - 2219-2840 (Electronic) IS - 1007-9327 (Print) IS - 1007-9327 (Linking) VI - 23 IP - 47 DP - 2017 Dec 21 TI - Rate of adverse events of gastroduodenal snare polypectomy for non-flat polyp is low: A prospective and multicenter study. PG - 8405-8414 LID - 10.3748/wjg.v23.i47.8405 [doi] AB - AIM: To evaluate the rate of adverse events (AEs) during consecutive gastric and duodenal polypectomies in several Spanish centers. METHODS: Polypectomies of protruded gastric or duodenal polyps >/= 5 mm using hot snare were prospectively included. Prophylactic measures of hemorrhage were allowed in predefined cases. AEs were defined and graded according to the lexicon recommended by the American Society for Gastrointestinal Endoscopy. Patients were followed for 48 h, one week and 1 mo after the procedure. RESULTS: 308 patients were included and a single polypectomy was performed in 205. Only 36 (11.7%) were on prior anticoagulant therapy. Mean polyp size was 15 +/- 8.9 mm (5-60) and in 294 cases (95.4%) were located in the stomach. Hemorrhage prophylaxis was performed in 219 (71.1%) patients. Nine patients presented AEs (2.9%), and 6 of them were bleeding (n = 6, 1.9%) (in 5 out of 6 AE, different types of endoscopic treatment were performed). Other 24 hemorrhagic episodes could be managed without any change in the outcome of the endoscopy and, consequently, were considered incidents. We did not find any independent risk factor of bleeding. CONCLUSION: Gastroduodenal polypectomy using prophylactic measures has a rate of AEs small enough to consider this procedure a safe and effective method for polyp resection independently of the polyp size and location. FAU - Cordova, Henry AU - Cordova H AD - Endoscopy Unit. Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, CIBERehd, Universitat de Barcelona, Barcelona 08036, Spain. FAU - Arguello, Lidia AU - Arguello L AD - Digestive Endoscopy Unit, Digestive Diseases Department, Gastrointestinal Endoscopy Research Group, IIS, La Fe Polytechnic University Hospital, Valencia 46026, Spain. FAU - Loras, Carme AU - Loras C AD - Hospital Universitari Mutua de Terrassa, CIBERehd, Terrassa 08221, Spain. FAU - Naranjo Rodriguez, Antonio AU - Naranjo Rodriguez A AD - Hospital Reina Sofia, Cordoba 14004, Spain. FAU - Riu Pons, Faust AU - Riu Pons F AD - Hospital Del Mar, Barcelona 08003, Spain. FAU - Gornals, Joan B AU - Gornals JB AD - Hospital Universitari de Bellvitge, IDIBELL, Universitat de Barcelona, Hospitalet de Llobregat, Barcelona 08907, Spain. FAU - Nicolas-Perez, David AU - Nicolas-Perez D AD - Hospital Universitario de Canarias, Santa Cruz de Tenerife 38320, Spain. FAU - Andujar Murcia, Xavier AU - Andujar Murcia X AD - Hospital Universitari Mutua de Terrassa, CIBERehd, Terrassa 08221, Spain. FAU - Hernandez, Luis AU - Hernandez L AD - Hospital Santos Reyes, Aranda de Duero, Burgos 09400, Spain. FAU - Santolaria, Santos AU - Santolaria S AD - Hospital San Jorge, Huesca 22004, Spain. FAU - Leal, Carles AU - Leal C AD - Consorci Hospitalari de Vic, Universitat de Vic, Vic 08500, Spain. FAU - Pons, Carles AU - Pons C AD - Hospital de Viladecans, Viladecans, Barcelona 08840, Spain. FAU - Perez-Cuadrado-Robles, Enrique AU - Perez-Cuadrado-Robles E AD - Hospital Morales Meseguer, Murcia 30008, Spain. FAU - Garcia-Bosch, Orlando AU - Garcia-Bosch O AD - Hospital Moises Broggi, Sant Joan Despi, Barcelona 08970, Spain. FAU - Papo Berger, Michel AU - Papo Berger M AD - Hospital Joan XXIII, Tarragona 43005, Spain. FAU - Ulla Rocha, Jose Luis AU - Ulla Rocha JL AD - Complejo Hospitalario de Pontevedra, Pontevedra 36164, Spain. FAU - Sanchez-Montes, Cristina AU - Sanchez-Montes C AD - Endoscopy Unit. Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, CIBERehd, Universitat de Barcelona, Barcelona 08036, Spain. FAU - Fernandez-Esparrach, Gloria AU - Fernandez-Esparrach G AD - Endoscopy Unit. Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, CIBERehd, Universitat de Barcelona, Barcelona 08036, Spain. mgfernan@clinic.ub.es. LA - eng PT - Journal Article PT - Multicenter Study PT - Observational Study PL - United States TA - World J Gastroenterol JT - World journal of gastroenterology JID - 100883448 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Duodenal Diseases/*surgery MH - Duodenum/pathology/surgery MH - Endoscopy, Gastrointestinal/*adverse effects/methods MH - Female MH - Humans MH - Incidence MH - Male MH - Microsurgery/*adverse effects/methods MH - Middle Aged MH - Polyps/*surgery MH - Postoperative Hemorrhage/*epidemiology/etiology/therapy MH - Prospective Studies MH - Risk Factors MH - Spain MH - Stomach/pathology/surgery MH - Stomach Diseases/*surgery MH - Young Adult PMC - PMC5743511 OTO - NOTNLM OT - Adverse events OT - Bleeding OT - Foregut OT - Gastroduodenal OT - Polypectomy OT - Protruded polyps COIS- Conflict-of-interest statement: None of the authors of this manuscript, Henry Cordova, Lidia Arguello, Carme Loras, Antonio Naranjo Rodriguez, Faust Riu Pons, Joan B Gornals, David Nicolas-Perez, Xavier Andujar Murcia, Luis Hernandez, Santos Santolaria, Carles Leal, Carles Pons, Enrique Perez-Cuadrado-Robles, Orlando Garcia-Bosch, Michel Papo Berger, Jose Luis Ulla Rocha, Cristina Sanchez-Montes, Gloria Fernandez-Esparrach have any conflicts of interest or financial ties to disclose. EDAT- 2018/01/09 06:00 MHDA- 2018/08/09 06:00 PMCR- 2017/12/21 CRDT- 2018/01/09 06:00 PHST- 2017/09/01 00:00 [received] PHST- 2017/10/03 00:00 [revised] PHST- 2017/10/26 00:00 [accepted] PHST- 2018/01/09 06:00 [entrez] PHST- 2018/01/09 06:00 [pubmed] PHST- 2018/08/09 06:00 [medline] PHST- 2017/12/21 00:00 [pmc-release] AID - 10.3748/wjg.v23.i47.8405 [doi] PST - ppublish SO - World J Gastroenterol. 2017 Dec 21;23(47):8405-8414. doi: 10.3748/wjg.v23.i47.8405.