PMID- 29319337 OWN - NLM STAT- MEDLINE DCOM- 20190902 LR - 20190902 IS - 2327-9109 (Electronic) IS - 2327-9095 (Linking) VI - 26 IP - 3 DP - 2019 May-Jun TI - Reliable change and minimum clinically important difference (MCID) of the Repeatable Battery for the Assessment of Neuropsychology Status (RBANS) in a heterogeneous dementia sample: Support for reliable change methods but not the MCID. PG - 268-274 LID - 10.1080/23279095.2017.1413575 [doi] AB - We compare reliable change scores and recently published anchor-based cutoffs for minimum clinically important difference (MCID) for the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in a sample of patients diagnosed with various forms of dementia. For memory clinic patients with dementia evaluated twice over a one-year interval (N = 53), observed retest RBANS index scores were compared with predicted retest index scores based on regression formulae developed from cognitively healthy older adults. Patient RBANS change scores were also compared to suggested MCID anchors. Patients with dementia demonstrated a reliable decline on most RBANS indices, with evidence that the Visuospatial/Constructional and Language Indices might be less sensitive to decline over time. Although there was consistency between MCID and reliable changes in this sample, there was a substantial proportion where the MCID was exceeded, with no reliable change. We attempted to create MCIDs from the Clinical Dementia Rating Sum of Box scores for RBANS reliable change scores, but failed to find significant associations. Overall, the findings support use of the regression based reliable change approach, but we caution use of the MCID approach for the RBANS. FAU - O'Connell, Megan E AU - O'Connell ME AD - a Department of Psychology , University of Saskatchewan , Saskatoon , Saskatoon , Canada. FAU - Gould, Benjamin AU - Gould B AD - a Department of Psychology , University of Saskatchewan , Saskatoon , Saskatoon , Canada. FAU - Ursenbach, Jake AU - Ursenbach J AD - a Department of Psychology , University of Saskatchewan , Saskatoon , Saskatoon , Canada. FAU - Enright, Joe AU - Enright J AD - b London Health Sciences Centre , London , United Kingdom. FAU - Morgan, Debra G AU - Morgan DG AD - c Canadian Centre for Health and Safety in Agriculture , University of Saskatchewan , Saskatchewan , Canada. LA - eng PT - Journal Article DEP - 20180110 PL - United States TA - Appl Neuropsychol Adult JT - Applied neuropsychology. Adult JID - 101584082 SB - IM MH - Aged MH - Aged, 80 and over MH - Dementia/*diagnosis MH - *Disease Progression MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Memory Disorders/*diagnosis MH - Middle Aged MH - *Minimal Clinically Important Difference MH - Neuropsychological Tests/*standards OTO - NOTNLM OT - Dementia OT - minimum clinically important difference OT - reliable change OT - serial assessment EDAT- 2018/01/11 06:00 MHDA- 2019/09/03 06:00 CRDT- 2018/01/11 06:00 PHST- 2018/01/11 06:00 [pubmed] PHST- 2019/09/03 06:00 [medline] PHST- 2018/01/11 06:00 [entrez] AID - 10.1080/23279095.2017.1413575 [doi] PST - ppublish SO - Appl Neuropsychol Adult. 2019 May-Jun;26(3):268-274. doi: 10.1080/23279095.2017.1413575. Epub 2018 Jan 10.