PMID- 29322820
OWN - NLM
STAT- MEDLINE
DCOM- 20181221
LR  - 20181221
IS  - 2169-5202 (Electronic)
IS  - 1550-0594 (Linking)
VI  - 49
IP  - 6
DP  - 2018 Nov
TI  - Reevaluation of the Critically Ill Patients With Nonconvulsive Status Epilepticus 
      by Using Salzburg Consensus Criteria.
PG  - 425-432
LID - 10.1177/1550059417752437 [doi]
AB  - OBJECTIVE: We aimed to assess the usefulness of the Salzburg Consensus Criteria 
      (SCC) for determining the prognosis of critically ill patients with nonconvulsive 
      status epilepticus (NCSE). METHODS: We retrospectively reviewed consecutive 
      patients with unconsciousness followed up in the intensive care unit (ICU). Three 
      clinical neurophysiologists, one of them blinded to clinical and laboratory data, 
      reevaluated all EEG data independently and determined NCSE according to SCC. The 
      incidence of NCSE and ictal EEG patterns and their relationship to clinical, 
      laboratory, neuroradiological, and prognostic findings were assessed. RESULTS: A 
      total of 107 consecutive patients with mean age 68.2 +/- 15.3 years (57 females) 
      were enrolled in the study. Primary neuronal injury was detected in 59 patients 
      (55.7%). Thirty-three patients (30.8%) were diagnosed as NCSE. While authors 
      decided to treat 33 patients (30.8%), 32 patients (29.9%) had been treated in 
      real-life evaluation. Clinical and EEG improvement were detected in 12 patients 
      (11.3%) in real-life treatment group showing correlation with lack of intubation 
      and ICU stay related to postsurgical event. Rate of mortality (45.8%) was high 
      showing association with systemic-metabolic etiology, severity of coma and 
      presence of "plus" modifiers in the EEG. CONCLUSION AND SIGNIFICANCE: Our 
      findings suggest that SCC is highly compatible with clinical practice in the 
      decision for treatment of patients with NCSE. The presence of "plus" modifiers in 
      the EEG was found to be associated with mortality in these patients and was a 
      significant marker for the high mortality rate.
FAU - Gungor Tuncer, Ozlem
AU  - Gungor Tuncer O
AD  - 1 Department of Neurology, Medical Faculty, Istanbul Bilim University, Istanbul, 
      Turkey.
FAU - Altindag, Ebru
AU  - Altindag E
AD  - 1 Department of Neurology, Medical Faculty, Istanbul Bilim University, Istanbul, 
      Turkey.
FAU - Ozel Yildiz, Sevda
AU  - Ozel Yildiz S
AD  - 2 Department of Biostatistics, Istanbul Medical Faculty, Istanbul University, 
      Istanbul, Turkey.
FAU - Nalbantoglu, Mecbure
AU  - Nalbantoglu M
AD  - 1 Department of Neurology, Medical Faculty, Istanbul Bilim University, Istanbul, 
      Turkey.
FAU - Acik, Mehmet Eren
AU  - Acik ME
AD  - 3 Department of Anesthesiology and Intensive Care, Medical Faculty, Istanbul 
      Bilim University, Istanbul, Turkey.
FAU - Tavukcu Ozkan, Sedef
AU  - Tavukcu Ozkan S
AD  - 4 Department of Anesthesiology and Intensive Care, Memorial Hizmet Hospital, 
      Istanbul, Turkey.
FAU - Baykan, Betul
AU  - Baykan B
AD  - 5 Department of Neurology, Istanbul Medical Faculty, Istanbul University, 
      Istanbul, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20180111
PL  - United States
TA  - Clin EEG Neurosci
JT  - Clinical EEG and neuroscience
JID - 101213033
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Consensus
MH  - Critical Illness
MH  - Electroencephalography/methods
MH  - Female
MH  - Humans
MH  - Intensive Care Units
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Retrospective Studies
MH  - Status Epilepticus/diagnosis/*therapy
MH  - Unconsciousness
OTO - NOTNLM
OT  - EEG monitoring
OT  - adult
OT  - electroencephalogram
OT  - intensive care unit
OT  - nonconvulsive status epilepticus
EDAT- 2018/01/13 06:00
MHDA- 2018/12/24 06:00
CRDT- 2018/01/12 06:00
PHST- 2018/01/13 06:00 [pubmed]
PHST- 2018/12/24 06:00 [medline]
PHST- 2018/01/12 06:00 [entrez]
AID - 10.1177/1550059417752437 [doi]
PST - ppublish
SO  - Clin EEG Neurosci. 2018 Nov;49(6):425-432. doi: 10.1177/1550059417752437. Epub 
      2018 Jan 11.