PMID- 29331621
OWN - NLM
STAT- MEDLINE
DCOM- 20180312
LR  - 20181202
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 196
DP  - 2018 Apr
TI  - Silver ion-enhanced particle-specific cytotoxicity of silver nanoparticles and 
      effect on the production of extracellular secretions of Phanerochaete 
      chrysosporium.
PG  - 575-584
LID - S0045-6535(17)32163-X [pii]
LID - 10.1016/j.chemosphere.2017.12.185 [doi]
AB  - This study investigated the influence of silver ions (Ag(+)) on the cytotoxicity 
      of silver nanoparticles (AgNPs) in Phanerochaete chrysosporium and noted the 
      degree of extracellular secretions in response to the toxicant's stress. Oxalate 
      production was elicited with moderate concentrations of 2,4-dichlorophenol 
      (2,4-DCP) and AgNPs reaching a plateau at 10 mg/L and 10 muM, respectively. 
      Increased oxalate accumulation was accompanied by higher activities of manganese 
      peroxidase (MnP) and lignin peroxidase (LiP). However, the secretion of oxalate, 
      MnP and LiP was significantly inhibited owing to Ag(+) incorporation into AgNP 
      solution. Production of extracellular polymeric substances (EPS) significantly 
      elevated with an increase in 2,4-DCP concentrations; however, after 24 h of 
      exposure to 100 mg/L 2,4-DCP, an obvious decrease in EPS occurred, indicating 
      that part of EPS could be consumed as carbon and energy sources to ameliorate 
      biological tolerance to toxic stress. Furthermore, AgNP-induced 
      "particle-specific" cytotoxicity was substantially enhanced with additional Ag(+) 
      as evidenced by its significant negative impact on cellular growth, plasma 
      membrane integrity, and morphological preservation compared with AgNPs at equal 
      Ag concentration.
CI  - Copyright (c) 2017 Elsevier Ltd. All rights reserved.
FAU - Huang, Zhenzhen
AU  - Huang Z
AD  - College of Environmental Science and Engineering, Hunan University, Changsha, 
      410082, PR China; Key Laboratory of Environmental Biology and Pollution Control 
      (Hunan University), Ministry of Education, Changsha, 410082, PR China.
FAU - Xu, Piao
AU  - Xu P
AD  - College of Environmental Science and Engineering, Hunan University, Changsha, 
      410082, PR China; Key Laboratory of Environmental Biology and Pollution Control 
      (Hunan University), Ministry of Education, Changsha, 410082, PR China.
FAU - Chen, Guiqiu
AU  - Chen G
AD  - College of Environmental Science and Engineering, Hunan University, Changsha, 
      410082, PR China; Key Laboratory of Environmental Biology and Pollution Control 
      (Hunan University), Ministry of Education, Changsha, 410082, PR China.
FAU - Zeng, Guangming
AU  - Zeng G
AD  - College of Environmental Science and Engineering, Hunan University, Changsha, 
      410082, PR China; Key Laboratory of Environmental Biology and Pollution Control 
      (Hunan University), Ministry of Education, Changsha, 410082, PR China. Electronic 
      address: zgming@hnu.edu.cn.
FAU - Chen, Anwei
AU  - Chen A
AD  - College of Resources and Environment, Hunan Agricultural University, Changsha, 
      410128, PR China. Electronic address: A.Chen@hunau.edu.cn.
FAU - Song, Zhongxian
AU  - Song Z
AD  - School of Municipal and Environmental Engineering, Henan University of Urban 
      Construction, Pingdingshan, 467036, PR China.
FAU - He, Kai
AU  - He K
AD  - College of Environmental Science and Engineering, Hunan University, Changsha, 
      410082, PR China; Key Laboratory of Environmental Biology and Pollution Control 
      (Hunan University), Ministry of Education, Changsha, 410082, PR China.
FAU - Yuan, Lei
AU  - Yuan L
AD  - College of Environmental Science and Engineering, Hunan University, Changsha, 
      410082, PR China; Key Laboratory of Environmental Biology and Pollution Control 
      (Hunan University), Ministry of Education, Changsha, 410082, PR China.
FAU - Li, Hui
AU  - Li H
AD  - College of Environmental Science and Engineering, Hunan University, Changsha, 
      410082, PR China; Key Laboratory of Environmental Biology and Pollution Control 
      (Hunan University), Ministry of Education, Changsha, 410082, PR China.
FAU - Hu, Liang
AU  - Hu L
AD  - College of Environmental Science and Engineering, Hunan University, Changsha, 
      410082, PR China; Key Laboratory of Environmental Biology and Pollution Control 
      (Hunan University), Ministry of Education, Changsha, 410082, PR China.
LA  - eng
PT  - Journal Article
DEP - 20171230
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Chlorophenols)
RN  - 0 (Ions)
RN  - 0 (Oxalates)
RN  - 0 (colloidal silver)
RN  - 3M4G523W1G (Silver)
RN  - EC 1.11.1.- (Peroxidases)
RN  - EC 1.11.1.- (lignin peroxidase)
RN  - EC 1.11.1.13 (manganese peroxidase)
RN  - R669TG1950 (2,4-dichlorophenol)
SB  - IM
MH  - Chlorophenols
MH  - Ions/*pharmacology
MH  - Metal Nanoparticles/*toxicity
MH  - Oxalates/metabolism
MH  - Peroxidases/metabolism
MH  - Phanerochaete/drug effects/*metabolism
MH  - Silver/*toxicity
OTO - NOTNLM
OT  - Enhanced "particle-specific" cytotoxicity
OT  - Extracellular secretions
OT  - Phanerochaete chrysosporium
OT  - Silver ions
OT  - Silver nanoparticles
EDAT- 2018/01/15 06:00
MHDA- 2018/03/13 06:00
CRDT- 2018/01/15 06:00
PHST- 2017/09/01 00:00 [received]
PHST- 2017/12/19 00:00 [revised]
PHST- 2017/12/28 00:00 [accepted]
PHST- 2018/01/15 06:00 [pubmed]
PHST- 2018/03/13 06:00 [medline]
PHST- 2018/01/15 06:00 [entrez]
AID - S0045-6535(17)32163-X [pii]
AID - 10.1016/j.chemosphere.2017.12.185 [doi]
PST - ppublish
SO  - Chemosphere. 2018 Apr;196:575-584. doi: 10.1016/j.chemosphere.2017.12.185. Epub 
      2017 Dec 30.