PMID- 29331737
OWN - NLM
STAT- MEDLINE
DCOM- 20190503
LR  - 20220409
IS  - 1532-2661 (Electronic)
IS  - 0034-5288 (Linking)
VI  - 118
DP  - 2018 Jun
TI  - Hematology reference intervals for neonatal Holstein calves.
PG  - 1-10
LID - S0034-5288(17)31016-0 [pii]
LID - 10.1016/j.rvsc.2018.01.002 [doi]
AB  - Data regarding hematologic reference intervals (RI) for neonatal calves have not 
      been published yet. The aims of this study were: a) to establish hematology RIs 
      for neonatal Holstein calves, b) to compare them with the RIs for lactating cows, 
      and c) to investigate the relationship of age and gender with the hematologic 
      profile of calves. Two-hundred and fifty-four clinically healthy Holstein calves 
      (1-9days old, from 30 farms) and 82 healthy Holstein cows (between 30 and 150days 
      in milk, from 10 farms) were blood sampled once for a complete blood count 
      evaluation, using the ADVIA 120 hematology analyzer. An additional blood sample 
      was collected from each calf for serum total protein concentration measurement. 
      RIs and age-related RIs were calculated with the Reference Value Advisor 
      freeware. Comparisons between calves and cows and between male and female calves 
      were performed with t-test or Mann-Whitney test. Red blood cell count (RBC), 
      white blood cell count (WBC), neutrophil, lymphocyte and platelet counts in 
      calves were higher, while mean corpuscular volume (MCV), mean corpuscular 
      hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were lower 
      than in cows. Lymphocyte and platelets showed a notable increase through age. 
      Finally, female calves had higher RBC, hematocrit and hemoglobin concentration 
      than males. Age-specific RIs should be used for the interpretation of the 
      complete blood count in Holstein calves.
CI  - Copyright (c) 2018 Elsevier Ltd. All rights reserved.
FAU - Panousis, Nikolaos
AU  - Panousis N
AD  - Clinic of Farm Animals, Faculty of Veterinary Medicine, School of Health 
      Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. 
      Electronic address: panousis@vet.auth.gr.
FAU - Siachos, Nektarios
AU  - Siachos N
AD  - Laboratory of Animal Husbandry, Faculty of Veterinary Medicine, School of Health 
      Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
FAU - Kitkas, Georgios
AU  - Kitkas G
AD  - Clinic of Farm Animals, Faculty of Veterinary Medicine, School of Health 
      Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
FAU - Kalaitzakis, Emmanouil
AU  - Kalaitzakis E
AD  - Clinic of Farm Animals, Faculty of Veterinary Medicine, School of Health 
      Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
FAU - Kritsepi-Konstantinou, Maria
AU  - Kritsepi-Konstantinou M
AD  - Diagnostic Laboratory, Faculty of Veterinary Medicine, School of Health Sciences, 
      Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
FAU - Valergakis, Georgios E
AU  - Valergakis GE
AD  - Laboratory of Animal Husbandry, Faculty of Veterinary Medicine, School of Health 
      Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20180109
PL  - England
TA  - Res Vet Sci
JT  - Research in veterinary science
JID - 0401300
SB  - IM
EIN - Res Vet Sci. 2019 Apr;123:184. PMID: 30682580
MH  - Animals
MH  - Animals, Newborn/*blood
MH  - Blood Cell Count
MH  - Cattle/*blood
MH  - Erythrocyte Count
MH  - Female
MH  - Hematologic Tests/methods/standards/*veterinary
MH  - Hematology/*standards
MH  - Lactation
MH  - Male
MH  - Reference Values
OTO - NOTNLM
OT  - ADVIA 120
OT  - Age
OT  - CBC
OT  - Cattle
OT  - Gender
EDAT- 2018/01/15 06:00
MHDA- 2019/05/06 06:00
CRDT- 2018/01/15 06:00
PHST- 2017/09/30 00:00 [received]
PHST- 2017/11/28 00:00 [revised]
PHST- 2018/01/08 00:00 [accepted]
PHST- 2018/01/15 06:00 [pubmed]
PHST- 2019/05/06 06:00 [medline]
PHST- 2018/01/15 06:00 [entrez]
AID - S0034-5288(17)31016-0 [pii]
AID - 10.1016/j.rvsc.2018.01.002 [doi]
PST - ppublish
SO  - Res Vet Sci. 2018 Jun;118:1-10. doi: 10.1016/j.rvsc.2018.01.002. Epub 2018 Jan 9.