PMID- 29332148 OWN - NLM STAT- MEDLINE DCOM- 20181024 LR - 20181113 IS - 1573-2983 (Electronic) IS - 0269-4042 (Linking) VI - 40 IP - 4 DP - 2018 Aug TI - Occurrence of pharmaceuticals and personal care products, and their associated environmental risks in a large shallow lake in north China. PG - 1525-1539 LID - 10.1007/s10653-018-0069-0 [doi] AB - Eighteen selected pharmaceuticals and personal care products (PPCPs), consisting of five non-antibiotic pharmaceuticals (N-APs), four sulfonamides (SAs), four tetracyclines (TCs), four macrolides (MCs), and one quinolone (QN) were detected in water, pore water, and sediment samples from Baiyangdian Lake, China. A total of 31 water samples and 29 sediment samples were collected in March 2017. Caffeine was detected with 100% frequency in surface water, pore water, and sediment samples. Carbamazepine was detected with 100% frequency in surface water and sediment samples. Five N-APs were prominent, with mean concentrations of 4.90-266.24 ng/l in surface water and 5.07-14.73 mug/kg in sediment samples. Four MCs were prominent, with mean concentrations of 0.97-29.92 ng/l in pore water samples. The total concentrations of the different classes of PPCPs followed the order: N-APs (53.26%) > MCs (25.39) > SAs (10.06%) > TCs (7.64%) > QNs (3.64%) in surface water; N-APs (42.70%) > MCs (25.43%) > TCs (14.69%) > SAs (13.90%) > QNs (3.24%) in sediment samples, and MCs (42.12%) > N-APs (34.80%) > SAs (11.71%) > TCs (7.48%) > QNs (3.88%) in pore water samples. The geographical differences of PPCP concentrations were largely due to anthropogenic activities. Sewage discharged from Baoding City and human activities around Baiyangdian Lake were the main sources of PPCPs in the lake. An environmental risk assessment for the upper quartile concentration was undertaken using calculated risk quotients and indicated a low or medium-high risk from 18 PPCPs in Baiyangdian Lake and its five upstream rivers. FAU - Zhang, Panwei AU - Zhang P AD - China Institute of Water Resources and Hydropower Research, Beijing, 100038, China. FAU - Zhou, Huaidong AU - Zhou H AD - China Institute of Water Resources and Hydropower Research, Beijing, 100038, China. FAU - Li, Kun AU - Li K AD - China Institute of Water Resources and Hydropower Research, Beijing, 100038, China. FAU - Zhao, Xiaohui AU - Zhao X AD - China Institute of Water Resources and Hydropower Research, Beijing, 100038, China. FAU - Liu, Qiaona AU - Liu Q AD - China Institute of Water Resources and Hydropower Research, Beijing, 100038, China. FAU - Li, Dongjiao AU - Li D AD - China Institute of Water Resources and Hydropower Research, Beijing, 100038, China. FAU - Zhao, Gaofeng AU - Zhao G AD - China Institute of Water Resources and Hydropower Research, Beijing, 100038, China. zhaogf@iwhr.com. LA - eng GR - 2012ZX07203-006/Major Science and Technology Project of Water Pollution control and management in China/ GR - 2018ZX07110-04/Major Science and Technology Project of Water Pollution control and management in China/ GR - Z171100000717010/Beijing Municipal Science and Technology Plan Project in China/ PT - Journal Article DEP - 20180113 PL - Netherlands TA - Environ Geochem Health JT - Environmental geochemistry and health JID - 8903118 RN - 0 (Cosmetics) RN - 0 (Pharmaceutical Preparations) RN - 0 (Water Pollutants, Chemical) SB - IM MH - China MH - Cosmetics/*analysis MH - Humans MH - *Lakes MH - Pharmaceutical Preparations/*analysis MH - Risk Assessment MH - Water Pollutants, Chemical/*analysis OTO - NOTNLM OT - Baiyangdian Lake OT - Occurrence OT - Pharmaceuticals and personal care products (PPCPs) OT - Risk assessment EDAT- 2018/01/15 06:00 MHDA- 2018/10/26 06:00 CRDT- 2018/01/15 06:00 PHST- 2017/07/29 00:00 [received] PHST- 2018/01/06 00:00 [accepted] PHST- 2018/01/15 06:00 [pubmed] PHST- 2018/10/26 06:00 [medline] PHST- 2018/01/15 06:00 [entrez] AID - 10.1007/s10653-018-0069-0 [pii] AID - 10.1007/s10653-018-0069-0 [doi] PST - ppublish SO - Environ Geochem Health. 2018 Aug;40(4):1525-1539. doi: 10.1007/s10653-018-0069-0. Epub 2018 Jan 13.