PMID- 29335328
OWN - NLM
STAT- MEDLINE
DCOM- 20190429
LR  - 20240403
IS  - 1478-5242 (Electronic)
IS  - 0960-1643 (Print)
IS  - 0960-1643 (Linking)
VI  - 68
IP  - 667
DP  - 2018 Feb
TI  - Walking prescription of 10 000 steps per day in patients with type 2 diabetes 
      mellitus: a randomised trial in Nigerian general practice.
PG  - e139-e145
LID - 10.3399/bjgp18X694613 [doi]
AB  - BACKGROUND: In clinical practice, translating the benefits of a sustained 
      physically active lifestyle on glycaemic control in patients with type 2 diabetes 
      mellitus (T2DM) is difficult. A walking prescription may be an effective 
      alternative. AIM: To examine the effect of a 10 000 steps per day prescription on 
      glycaemic control of patients with T2DM. DESIGN AND SETTING: Forty-six adults 
      with T2DM attending a general outpatient clinic were randomised into two equal 
      groups. The intervention group was given goals to accumulate 10 000 steps per day 
      for 10 weeks, whereas the control group maintained their normal activity habits. 
      METHOD: Daily step count was measured with waist-mounted pedometer and baseline 
      and endline average steps per day. Glycosylated haemoglobin (HbA1c), 
      anthropometric, and cardiovascular measurements were also obtained. An 
      intention-to-treat analysis was done. RESULTS: The average baseline step count 
      was 4505 steps per day for all participants, and the average step count in the 
      intervention group for the last 4 weeks of the study period was higher by 2913 
      steps per day (95% confidence interval [CI] = 1274 to 4551, F (2, 37.7) = 18.90, 
      P<0.001). Only 6.1% of the intervention group participants achieved the 10 000 
      steps per day goal. The mean baseline HbA1c was 6.6% (range = 5.3 to 9.0). 
      Endline HbA1c was lower in the intervention group than in the control group (mean 
      difference -0.74%, 95% CI = -1.32 to -0.02, F = 12.92, P = 0.015) after adjusting 
      for baseline HbA1c. There was no change in anthropometric and cardiovascular 
      indices. CONCLUSION: Adherence to 10 000 steps per day prescription is low but 
      may still be associated with improved glycaemic control in T2DM. Motivational 
      strategies for better adherence would improve glycaemic control.
CI  - (c) British Journal of General Practice 2018.
FAU - Fayehun, Ayorinde F
AU  - Fayehun AF
AD  - Department of Family Medicine.
FAU - Olowookere, Olufemi O
AU  - Olowookere OO
AD  - Department of Family Medicine, University College Hospital, Ibadan.
FAU - Ogunbode, Adetola M
AU  - Ogunbode AM
AD  - Department of Family Medicine, University College Hospital, Ibadan.
FAU - Adetunji, Adedotun A
AU  - Adetunji AA
AD  - Department of Family Medicine, University College Hospital, Ibadan.
FAU - Esan, Arinola
AU  - Esan A
AD  - Endocrinology Unit, Department of Internal Medicine, University College Hospital, 
      Ibadan.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20180115
PL  - England
TA  - Br J Gen Pract
JT  - The British journal of general practice : the journal of the Royal College of 
      General Practitioners
JID - 9005323
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (hemoglobin A1c protein, human)
SB  - IM
MH  - Accelerometry
MH  - Adult
MH  - Diabetes Mellitus, Type 2/epidemiology/physiopathology/*therapy
MH  - *Exercise Therapy
MH  - Female
MH  - General Practice
MH  - Glycated Hemoglobin/*metabolism
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nigeria
MH  - Patient Compliance/*statistics & numerical data
MH  - Treatment Outcome
MH  - *Walking
MH  - Young Adult
PMC - PMC5774965
OTO - NOTNLM
OT  - Nigeria
OT  - blood glucose
OT  - general practice
OT  - physical activity
OT  - type 2 diabetes mellitus
OT  - walking
EDAT- 2018/01/18 06:00
MHDA- 2019/04/30 06:00
PMCR- 2019/02/01
CRDT- 2018/01/17 06:00
PHST- 2017/06/04 00:00 [received]
PHST- 2017/10/05 00:00 [accepted]
PHST- 2018/01/18 06:00 [pubmed]
PHST- 2019/04/30 06:00 [medline]
PHST- 2018/01/17 06:00 [entrez]
PHST- 2019/02/01 00:00 [pmc-release]
AID - bjgp18X694613 [pii]
AID - 10.3399/bjgp18X694613 [doi]
PST - ppublish
SO  - Br J Gen Pract. 2018 Feb;68(667):e139-e145. doi: 10.3399/bjgp18X694613. Epub 2018 
      Jan 15.