PMID- 29339240 OWN - NLM STAT- MEDLINE DCOM- 20190102 LR - 20190102 IS - 1097-6787 (Electronic) IS - 0190-9622 (Linking) VI - 79 IP - 1 DP - 2018 Jul TI - Prevalence of type 2 diabetes mellitus among patients with hidradenitis suppurativa in the United States. PG - 71-76 LID - S0190-9622(18)30098-7 [pii] LID - 10.1016/j.jaad.2018.01.014 [doi] AB - BACKGROUND: Few studies have evaluated the relationship between hidradenitis suppurativa (HS) and type 2 diabetes mellitus (T2DM), and the existing data show conflicting results. OBJECTIVE: To determine the prevalence of T2DM among patients with HS and identify at-risk demographic subgroups. METHODS: Cross-sectional analysis identifying T2DM among patients with and without HS from a demographically heterogeneous population-based sample of more than 50 million patients in the United States. RESULTS: The overall prevalence of T2DM among patients with HS was 24.8% (10,705 of 43,105) compared with 15.6% (1,993,320 of 12,527,570) among patients without HS. The prevalence was highest among patients with HS who were male (3045 of 10,785 [28.2%]), older (1945 of 3950 [49.2%]), nonwhite (4665 of 17,495 [26.7%]), obese (9065 of 30,855 [29.4%]), tobacco smokers (6880 of 25,005 [27.5%]), hypertensive (8595 of 19,610 [43.8%]), and hyperlipidemic (7965 of 17,190 [46.3%]). In univariable and multivariable analyses, patients with HS had 1.75 (95% confidence interval [CI], 1.71-1.79) and 1.58 (95% CI, 1.54-1.62) times the odds, respectively, of having T2DM. HS was associated with T2DM across all demographic subgroups. The association was stronger for younger patients (an OR of 1.67 and 95% CI of 1.60-1.72 for ages 18-44 years vs an OR of 1.50 and 95% CI of 1.41-1.61 for ages >/=65 years). LIMITATIONS: We lacked information on HS disease severity. CONCLUSION: Patients with HS with risk factors, signs, or symptoms of T2DM should be screened. CI - Copyright (c) 2018 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved. FAU - Garg, Amit AU - Garg A AD - Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York. Electronic address: amgarg@northwell.edu. FAU - Birabaharan, Morgan AU - Birabaharan M AD - Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York. FAU - Strunk, Andrew AU - Strunk A AD - Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York. LA - eng PT - Comparative Study PT - Journal Article DEP - 20180112 PL - United States TA - J Am Acad Dermatol JT - Journal of the American Academy of Dermatology JID - 7907132 SB - IM MH - Adolescent MH - Adult MH - Age Distribution MH - Aged MH - Analysis of Variance MH - Comorbidity MH - Cross-Sectional Studies MH - Databases, Factual MH - Diabetes Mellitus, Type 2/*diagnosis/*epidemiology MH - Female MH - Hidradenitis Suppurativa/*diagnosis/*epidemiology MH - Humans MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Obesity/epidemiology MH - Prevalence MH - Prognosis MH - Risk Factors MH - Severity of Illness Index MH - Sex Distribution MH - Smoking/epidemiology MH - United States/epidemiology OTO - NOTNLM OT - United States OT - diabetes mellitus OT - hidradenitis suppurativa OT - prevalence EDAT- 2018/01/18 06:00 MHDA- 2019/01/03 06:00 CRDT- 2018/01/18 06:00 PHST- 2017/11/28 00:00 [received] PHST- 2018/01/02 00:00 [revised] PHST- 2018/01/03 00:00 [accepted] PHST- 2018/01/18 06:00 [pubmed] PHST- 2019/01/03 06:00 [medline] PHST- 2018/01/18 06:00 [entrez] AID - S0190-9622(18)30098-7 [pii] AID - 10.1016/j.jaad.2018.01.014 [doi] PST - ppublish SO - J Am Acad Dermatol. 2018 Jul;79(1):71-76. doi: 10.1016/j.jaad.2018.01.014. Epub 2018 Jan 12.