PMID- 29343025
OWN - NLM
STAT- MEDLINE
DCOM- 20181211
LR  - 20181211
IS  - 0376-2491 (Print)
IS  - 0376-2491 (Linking)
VI  - 98
IP  - 1
DP  - 2018 Jan 2
TI  - [Correlation between the parameters of acoustic cardiography and BNP, LVEF and 
      cardiac function grading in patients with chronic heart failure].
PG  - 25-29
LID - 10.3760/cma.j.issn.0376-2491.2018.01.006 [doi]
AB  - Objective: To explore the correlation between the parameters of the new 
      generation of Acoustic Cardiography and brain natriuretic peptide (BNP), left 
      ventricular ejection fraction (LVEF) and cardiac function grading in the 
      diagnosis of heart failure. Methods: One hundred and sixty-eight inpatients, who 
      were hospitalized in Department of Cardiology, Haikou People's Hospital from May 
      2016 to July 2017, were enrolled as heart failure group, including NYHA class 
      Ⅰ(n=29), NYHA class Ⅱ(n=40), NYHA class Ⅲ(n=64), NYHA class Ⅳ (n=35). And 
      eighty-seven patients with normal cardiac function were selected as healthy 
      control group. The data of the two groups were analyzed after the Acoustic 
      Cardiography test, BNP determination and LVEF examination. Results: The 
      differences in QRS duration, electromechanical activation time (EMAT), EMAT%, 
      systolic dysfunction index (SDI), third heart sound (S3) and other indicators 
      among the groups with different levels of cardiac function were statistically 
      significant (P<0.05). The difference in left ventricular systolic time (LVST) 
      between the cardiac function grade Ⅰ and healthy group was not significant 
      (P>0.05), while the differences among the rest groups were significant. There was 
      a positive correlation between QRS duration, EMAT%, SDI, S3 and BNP (t=9.46, 
      11.38, 12.14, 9.67, respectively, P<0.05); LVST and BNP were negatively 
      correlated (t=-14.27, P<0.05). There was a negative correlation between QRS 
      duration, EMAT%, SDI, S3 and LVEF (t=11.24, -8.764, -2.393, -0.579, respectively, 
      P<0.05). There was a positive correlation between LVST and LVEF (t=23.48, 
      P<0.05). There was a positive correlation between QRS duration, EMAT%, SDI, S3 
      and cardiac function grading (beta=0.003, 0.234, 0.419, 0.352, respectively, 
      P<0.05). There was a negative correlation between LVST and cardiac function grade 
      (beta=-0.021, P<0.05). Conclusion: The parameters of the Acoustic Cardiography test 
      (EMAT%, EMAT, SDI, S3 ) are closely related to BNP, LVEF and cardiac function 
      grading, and can be used as assistant indexes for the diagnosis and evaluation of 
      heart failure.
FAU - Xie, Q
AU  - Xie Q
AD  - Department of Cardiology, Central South University Xiangya School of Medicine 
      Affiliated Haikou Hospital, Haikou 570208, China.
FAU - Zhang, F W
AU  - Zhang FW
FAU - Chen, M S
AU  - Chen MS
FAU - Zhang, Y X
AU  - Zhang YX
FAU - Ren, L Q
AU  - Ren LQ
FAU - Xing, B
AU  - Xing B
FAU - Li, D Y
AU  - Li DY
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Yi Xue Za Zhi
JT  - Zhonghua yi xue za zhi
JID - 7511141
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Chronic Disease
MH  - *Heart Failure
MH  - Humans
MH  - Natriuretic Peptide, Brain
MH  - Systole
MH  - Ventricular Dysfunction, Left
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - Acoustic cardiography
OT  - Brain natriuretic peptide
OT  - Cardiac function grading
OT  - Heart Failure
OT  - Left ventricular ejection fraction
EDAT- 2018/01/19 06:00
MHDA- 2018/12/12 06:00
CRDT- 2018/01/19 06:00
PHST- 2018/01/19 06:00 [entrez]
PHST- 2018/01/19 06:00 [pubmed]
PHST- 2018/12/12 06:00 [medline]
AID - 10.3760/cma.j.issn.0376-2491.2018.01.006 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Za Zhi. 2018 Jan 2;98(1):25-29. doi: 
      10.3760/cma.j.issn.0376-2491.2018.01.006.