PMID- 29350278
OWN - NLM
STAT- MEDLINE
DCOM- 20180810
LR  - 20181113
IS  - 1439-6327 (Electronic)
IS  - 1439-6319 (Linking)
VI  - 118
IP  - 3
DP  - 2018 Mar
TI  - Lower body blood flow restriction training may induce remote muscle strength 
      adaptations in an active unrestricted arm.
PG  - 617-627
LID - 10.1007/s00421-018-3806-2 [doi]
AB  - PURPOSE: We examined the concurrent characteristics of the remote development of 
      strength and cross-sectional area (CSA) of upper body skeletal muscle in response 
      to lower body resistance training performed with an applied blood flow 
      restriction (BFR). METHODS: Males allocated to an experimental BFR group (EXP; 
      n = 12) or a non-BFR control group (CON; n = 12) completed 7-weeks of resistance 
      training comprising three sets of unilateral bicep curls [50% 1-repetition 
      maximum (1-RM)], then four sets of bilateral knee extension and flexion exercises 
      (30% 1-RM). EXP performed leg exercises with an applied BFR (60% limb occlusion 
      pressure). 1-RM strength was measured using bilateral leg exercises and 
      unilateral bicep curls in both trained and untrained arms. Muscle CSA was 
      measured via peripheral quantitative computed tomography in the dominant leg and 
      both arms. RESULTS: 1-RM in the trained arm increased more in EXP (2.5 +/- 0.4 kg; 
      mean +/- SEM) than the contralateral untrained arm (0.8 +/- 0.4 kg), and the trained 
      arm of CON (0.6 +/- 0.3 kg, P < 0.05). The increase in knee extension 1-RM was 
      twofold that of CON (P < 0.01). Knee flexion 1-RM, leg CSA, and trained arm CSA 
      increased similarly between groups (P > 0.05), while untrained arm CSA did not 
      change (P > 0.05). CONCLUSION: Lower limb BFR training increased trained arm 
      strength more than the contralateral untrained arm, and the trained arm of 
      controls. However, there was no additional effect on muscle CSA. These findings 
      support evidence for a BFR training-derived remote strength transfer that may be 
      relevant to populations with localised movement disorders.
FAU - May, Anthony K
AU  - May AK
AUID- ORCID: 0000-0002-4028-949X
AD  - Institute for Physical Activity and Nutrition, School of Exercise and Nutrition 
      Sciences, Deakin University, Melbourne Campus at Burwood, Burwood, 3125, VIC, 
      Australia. a.may@deakin.edu.au.
FAU - Russell, Aaron P
AU  - Russell AP
AD  - Institute for Physical Activity and Nutrition, School of Exercise and Nutrition 
      Sciences, Deakin University, Melbourne Campus at Burwood, Burwood, 3125, VIC, 
      Australia.
FAU - Warmington, Stuart A
AU  - Warmington SA
AD  - Institute for Physical Activity and Nutrition, School of Exercise and Nutrition 
      Sciences, Deakin University, Melbourne Campus at Burwood, Burwood, 3125, VIC, 
      Australia.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20180119
PL  - Germany
TA  - Eur J Appl Physiol
JT  - European journal of applied physiology
JID - 100954790
SB  - IM
MH  - *Adaptation, Physiological
MH  - Adult
MH  - Arm/*physiology
MH  - Humans
MH  - Intermittent Pneumatic Compression Devices
MH  - Leg/*blood supply/physiology
MH  - Male
MH  - *Muscle Strength
MH  - Muscle, Skeletal/*physiology
MH  - Physical Conditioning, Human/instrumentation/*methods
MH  - *Regional Blood Flow
OTO - NOTNLM
OT  - Blood flow restriction
OT  - Hypertrophy
OT  - Remote
OT  - Resistance
OT  - Strength
EDAT- 2018/01/20 06:00
MHDA- 2018/08/11 06:00
CRDT- 2018/01/20 06:00
PHST- 2017/06/08 00:00 [received]
PHST- 2018/01/14 00:00 [accepted]
PHST- 2018/01/20 06:00 [pubmed]
PHST- 2018/08/11 06:00 [medline]
PHST- 2018/01/20 06:00 [entrez]
AID - 10.1007/s00421-018-3806-2 [pii]
AID - 10.1007/s00421-018-3806-2 [doi]
PST - ppublish
SO  - Eur J Appl Physiol. 2018 Mar;118(3):617-627. doi: 10.1007/s00421-018-3806-2. Epub 
      2018 Jan 19.