PMID- 29350788
OWN - NLM
STAT- MEDLINE
DCOM- 20180828
LR  - 20180828
IS  - 1399-3038 (Electronic)
IS  - 0905-6157 (Linking)
VI  - 29
IP  - 3
DP  - 2018 May
TI  - Reliability and validity of the Atopic Dermatitis Symptom Score (ADSS).
PG  - 290-295
LID - 10.1111/pai.12865 [doi]
AB  - BACKGROUND: We have developed the Atopic Dermatitis Symptom Score (ADSS) by which 
      patients or parents can easily assess and record AD symptoms on a daily basis in 
      a smartphone application. The aim of this study was to evaluate the reliability 
      and validity of the ADSS. METHODS: We enrolled 307 children and adolescents with 
      AD. Parents or caregivers were asked to record daily symptoms of the patients 
      (itching, sleep disturbance, erythema, dryness, oozing, and edema) using a scale 
      of 0-4. Statistical analyses consisted of the test-retest reliability, concurrent 
      validity, minimal clinically important difference (MCID), responsiveness, floor 
      or ceiling effects, and screening accuracy. Receiver-operating characteristic 
      analyses were conducted to evaluate the ADSS cutoff point for predicting severe 
      AD (SCORing AD [SCORAD] >/=40). RESULTS: Test-retest reliability between daytime 
      and night-time ADSS was good (intraclass correlation coefficient, 0.82 [95% CI: 
      0.70-0.90]). An increase in ADSS was significantly associated with an increase in 
      SCORAD (r = 0.64, P < .0001) (concurrent validity). The MCID was 4.1 points for 
      the ADSS. There was a significant association between changes in ADSS and SCORAD 
      (r = 0.56, P < .0001), indicating good responsiveness. At the optimal ADSS cutoff 
      value of 7.0, sensitivity, specificity, and positive and negative predictive 
      values were 88.4%, 78.6%, 21.1%, and 99.1%, respectively (screening accuracy). 
      CONCLUSIONS: The ADSS can be a useful tool for self-assessment of skin symptoms 
      in children with AD.
CI  - (c) 2018 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.
FAU - Lee, J Y
AU  - Lee JY
AD  - Department of Pediatrics, Hallym University Hangang Sacred Heart Hospital, Seoul, 
      Korea.
FAU - Kim, M
AU  - Kim M
AD  - Department of Pediatrics, Hallym University Dongtan Sacred Heart Hospital, 
      Hwaseong, Korea.
FAU - Yang, H-K
AU  - Yang HK
AD  - Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School 
      of Medicine, Seoul, Korea.
FAU - Kim, H M
AU  - Kim HM
AD  - Environmental Health Center for Atopic Diseases, Samsung Medical Center, Seoul, 
      Korea.
FAU - Cho, J
AU  - Cho J
AD  - Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School 
      of Medicine, Seoul, Korea.
FAU - Kim, Y-M
AU  - Kim YM
AD  - Environmental Health Center for Atopic Diseases, Samsung Medical Center, Seoul, 
      Korea.
FAU - Lim, I S
AU  - Lim IS
AD  - Department of Pediatrics, Chung-Ang University Hospital, Seoul, Korea.
FAU - Cheong, H-K
AU  - Cheong HK
AD  - Department of Social and Preventive Medicine, Sungkyunkwan University School of 
      Medicine, Suwon, Korea.
AD  - Samsung Biomedical Research Institute, Sungkyunkwan University School of 
      Medicine, Seoul, Korea.
FAU - Kim, H S
AU  - Kim HS
AD  - Statistics and Data Center, Samsung Biomedical Research Institute, Seoul, Korea.
FAU - Sohn, I
AU  - Sohn I
AD  - Statistics and Data Center, Samsung Biomedical Research Institute, Seoul, Korea.
FAU - Kim, J
AU  - Kim J
AUID- ORCID: 0000-0001-8493-2881
AD  - Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School 
      of Medicine, Seoul, Korea.
AD  - Environmental Health Center for Atopic Diseases, Samsung Medical Center, Seoul, 
      Korea.
FAU - Ahn, K
AU  - Ahn K
AUID- ORCID: 0000-0001-7751-9829
AD  - Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School 
      of Medicine, Seoul, Korea.
AD  - Environmental Health Center for Atopic Diseases, Samsung Medical Center, Seoul, 
      Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180225
PL  - England
TA  - Pediatr Allergy Immunol
JT  - Pediatric allergy and immunology : official publication of the European Society 
      of Pediatric Allergy and Immunology
JID - 9106718
SB  - IM
MH  - Adolescent
MH  - Caregivers
MH  - Child
MH  - Child, Preschool
MH  - Dermatitis, Atopic/*diagnosis
MH  - Female
MH  - Humans
MH  - Infant
MH  - Longitudinal Studies
MH  - Male
MH  - Mass Screening/*methods
MH  - Mobile Applications
MH  - Parents
MH  - ROC Curve
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Severity of Illness Index
MH  - Smartphone
OTO - NOTNLM
OT  - assessment
OT  - atopic dermatitis
OT  - reliability
OT  - severity
OT  - validity
EDAT- 2018/01/20 06:00
MHDA- 2018/08/29 06:00
CRDT- 2018/01/20 06:00
PHST- 2018/01/11 00:00 [accepted]
PHST- 2018/01/20 06:00 [pubmed]
PHST- 2018/08/29 06:00 [medline]
PHST- 2018/01/20 06:00 [entrez]
AID - 10.1111/pai.12865 [doi]
PST - ppublish
SO  - Pediatr Allergy Immunol. 2018 May;29(3):290-295. doi: 10.1111/pai.12865. Epub 
      2018 Feb 25.