PMID- 2935189
OWN - NLM
STAT- MEDLINE
DCOM- 19860326
LR  - 20190613
IS  - 0006-2960 (Print)
IS  - 0006-2960 (Linking)
VI  - 24
IP  - 25
DP  - 1985 Dec 3
TI  - Noncovalently and covalently bound lipid on the receptor for immunoglobulin E.
PG  - 7342-8
AB  - We describe experiments which indicate that lipids interact with the receptor for 
      immunoglobulin E (IgE) in several ways. Evidence for loosely bound lipid comes 
      from observations on the special conditions that are required in order to 
      oxidatively iodinate the alpha chain of the receptor in IgE-receptor complexes. 
      Evidence for tightly, but still noncovalently, bound lipids comes from studies on 
      the lipids required to inhibit dissociation of the subunits of the receptor in 
      micellar detergent. Finally, biosynthetic studies indicate that the subunits of 
      the receptor contain ester-linked fatty acids. The latter modification appears to 
      take place on receptors that have already been inserted into the plasma membrane.
FAU - Kinet, J P
AU  - Kinet JP
FAU - Quarto, R
AU  - Quarto R
FAU - Perez-Montfort, R
AU  - Perez-Montfort R
FAU - Metzger, H
AU  - Metzger H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Biochemistry
JT  - Biochemistry
JID - 0370623
RN  - 0 (Detergents)
RN  - 0 (Iodine Radioisotopes)
RN  - 0 (Macromolecular Substances)
RN  - 0 (Micelles)
RN  - 0 (Phospholipids)
RN  - 0 (Receptors, Fc)
RN  - 0 (Receptors, IgE)
RN  - 0 (Receptors, Immunologic)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Animals
MH  - Basophils
MH  - Cell Line
MH  - Detergents
MH  - Immunoglobulin E/*metabolism
MH  - Iodine Radioisotopes
MH  - Kinetics
MH  - Leukemia, Experimental
MH  - Liver/metabolism
MH  - Macromolecular Substances
MH  - Mice
MH  - Micelles
MH  - Phospholipids/*metabolism
MH  - Protein Binding
MH  - Rabbits
MH  - Rats
MH  - Receptors, Fc/isolation & purification/*metabolism
MH  - Receptors, IgE
MH  - Receptors, Immunologic/isolation & purification/*metabolism
EDAT- 1985/12/03 00:00
MHDA- 1985/12/03 00:01
CRDT- 1985/12/03 00:00
PHST- 1985/12/03 00:00 [pubmed]
PHST- 1985/12/03 00:01 [medline]
PHST- 1985/12/03 00:00 [entrez]
AID - 10.1021/bi00346a048 [doi]
PST - ppublish
SO  - Biochemistry. 1985 Dec 3;24(25):7342-8. doi: 10.1021/bi00346a048.