PMID- 29360907
OWN - NLM
STAT- MEDLINE
DCOM- 20180807
LR  - 20180807
IS  - 2326-6929 (Electronic)
IS  - 0011-4162 (Linking)
VI  - 100
IP  - 6
DP  - 2017 Dec
TI  - Lichen planus and lichenoid drug eruption after vaccination.
PG  - E6-E20
AB  - Lichen planus (LP) and lichenoid drug eruptions (LDEs) uncommonly occur after 
      vaccination, especially for hepatitis B and influenza. The key initiating event 
      that leads to the development of postimmunization LP or LDE is not well 
      understood. There have been prior reports of an association between several 
      vaccines and LP. In this study, we aim to characterize and review cases of LP and 
      LDE after vaccination from the Vaccine Adverse Event Reporting System (VAERS) 
      national database in the United States. Information on vaccine-associated LP and 
      LDE was retrieved from the database (July 1990 to November 2014) to examine the 
      frequency of LP or LDE after vaccination. Hepatitis B, influenza, and herpes 
      zoster vaccines were the 3 most commonly associated vaccines. Patients with LP or 
      LDE were significantly older compared to the reported adverse events (AEs) 
      overall (P<.001). The median age of onset for LP and LDE was 47 years. The median 
      time of onset of AEs was 14 days. It is important to obtain recent vaccination 
      history in patients presenting with new-onset LP or LDE.
FAU - Lai, Yi C
AU  - Lai YC
AD  - Harvard School of Public Health, Boston, Massachusetts, USA.
FAU - Yew, Yik W
AU  - Yew YW
AD  - Harvard School of Public Health, Boston, Massachusetts, USA; and National Skin 
      Centre, Singapore.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cutis
JT  - Cutis
JID - 0006440
RN  - 0 (Vaccines)
SB  - IM
MH  - Adverse Drug Reaction Reporting Systems
MH  - Age Factors
MH  - Female
MH  - Humans
MH  - Lichen Planus/*chemically induced/epidemiology
MH  - Lichenoid Eruptions/*chemically induced/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Time Factors
MH  - United States/epidemiology
MH  - Vaccination/*adverse effects/methods
MH  - Vaccines/administration & dosage/*adverse effects
EDAT- 2018/01/24 06:00
MHDA- 2018/08/08 06:00
CRDT- 2018/01/24 06:00
PHST- 2018/01/24 06:00 [entrez]
PHST- 2018/01/24 06:00 [pubmed]
PHST- 2018/08/08 06:00 [medline]
PST - ppublish
SO  - Cutis. 2017 Dec;100(6):E6-E20.