PMID- 29361886 OWN - NLM STAT- MEDLINE DCOM- 20190221 LR - 20190221 IS - 1758-1052 (Electronic) IS - 0956-4624 (Linking) VI - 29 IP - 8 DP - 2018 Jul TI - Sequential occurrence of Graves' disease and immune thrombocytopenic purpura as manifestations of immune reconstitution inflammatory syndrome in an HIV-infected patient. PG - 834-836 LID - 10.1177/0956462417752824 [doi] AB - Immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients after initiating antiretroviral therapy usually involves worsening manifestations of overt infectious disease. Here, we describe a sporadic case of a late-diagnosed HIV-positive man who developed Graves' disease as the first noninfectious IRIS followed by immune thrombocytopenic purpura as the second noninfectious IRIS. FAU - Okazaki, Masafumi AU - Okazaki M AD - 1 Department of Pharmacy, Kochi Medical School Hospital, Nankoku, Japan. FAU - Nakamura, Miho AU - Nakamura M AD - 2 Department of General Medicine, Kochi Medical School Hospital, Nankoku, Japan. FAU - Imai, Akiko AU - Imai A AD - 1 Department of Pharmacy, Kochi Medical School Hospital, Nankoku, Japan. FAU - Asagiri, Tadashi AU - Asagiri T AD - 3 Department of Clinical Laboratory, Kochi Medical School Hospital, Nankoku, Japan. FAU - Takeuchi, Seisho AU - Takeuchi S AD - 2 Department of General Medicine, Kochi Medical School Hospital, Nankoku, Japan. LA - eng PT - Case Reports PT - Journal Article DEP - 20180123 PL - England TA - Int J STD AIDS JT - International journal of STD & AIDS JID - 9007917 RN - 0 (Anti-Retroviral Agents) RN - 554Z48XN5E (Methimazole) SB - IM MH - AIDS-Related Opportunistic Infections/*chemically induced/drug therapy/immunology MH - Aged MH - Anti-Retroviral Agents/therapeutic use MH - Antiretroviral Therapy, Highly Active/*adverse effects MH - CD4 Lymphocyte Count MH - CD4-Positive T-Lymphocytes/*immunology MH - Graves Disease/diagnosis/drug therapy/*immunology MH - HIV MH - HIV Infections/*complications/drug therapy MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/*chemically induced/complications/*immunology/pathology MH - Immunocompromised Host MH - Male MH - Methimazole/therapeutic use MH - Purpura, Thrombocytopenic, Idiopathic/diagnosis/drug therapy/*immunology MH - Treatment Outcome OTO - NOTNLM OT - Antiretroviral therapy OT - Graves' disease OT - HIV OT - IRIS OT - immune thrombocytopenic purpura EDAT- 2018/01/25 06:00 MHDA- 2019/02/23 06:00 CRDT- 2018/01/25 06:00 PHST- 2018/01/25 06:00 [pubmed] PHST- 2019/02/23 06:00 [medline] PHST- 2018/01/25 06:00 [entrez] AID - 10.1177/0956462417752824 [doi] PST - ppublish SO - Int J STD AIDS. 2018 Jul;29(8):834-836. doi: 10.1177/0956462417752824. Epub 2018 Jan 23.