PMID- 29372172
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220318
IS  - 2328-8957 (Print)
IS  - 2328-8957 (Electronic)
IS  - 2328-8957 (Linking)
VI  - 5
IP  - 1
DP  - 2018 Jan
TI  - Cryptococcal Disease in the Era of "Test and Treat": Is There Cause for Concern?
PG  - ofx274
LID - 10.1093/ofid/ofx274 [doi]
LID - ofx274
AB  - Treatment of cryptococcosis requires deferred initiation of antiretroviral 
      therapy (ART). Early ART initiation may be detrimental in the context of 
      cryptococcal infection by increasing the risk of immune reconstitution 
      inflammatory syndrome (IRIS). We present 3 cases where early ART initiation in 
      the presence of unrecognized cryptococcal disease had fatal outcomes.
FAU - Abassi, Mahsa
AU  - Abassi M
AD  - Infectious Diseases Institute, Kampala, Uganda.
AD  - University of Minnesota, Minneapolis, Minnesota.
FAU - Rhein, Joshua
AU  - Rhein J
AD  - Infectious Diseases Institute, Kampala, Uganda.
AD  - University of Minnesota, Minneapolis, Minnesota.
FAU - Meya, David B
AU  - Meya DB
AD  - Infectious Diseases Institute, Kampala, Uganda.
AD  - University of Minnesota, Minneapolis, Minnesota.
AD  - School of Medicine, College of Health Sciences, Makerere University, Kampala, 
      Uganda.
FAU - Boulware, David R
AU  - Boulware DR
AD  - University of Minnesota, Minneapolis, Minnesota.
LA  - eng
GR  - K01 TW010268/TW/FIC NIH HHS/United States
GR  - R01 NS086312/NS/NINDS NIH HHS/United States
GR  - R25 TW009345/TW/FIC NIH HHS/United States
GR  - T32 AI055433/AI/NIAID NIH HHS/United States
PT  - Journal Article
DEP - 20171226
PL  - United States
TA  - Open Forum Infect Dis
JT  - Open forum infectious diseases
JID - 101637045
PMC - PMC5777480
OTO - NOTNLM
OT  - HIV
OT  - cryptococcal immune reconstitution syndrome
OT  - test and treat
EDAT- 2018/01/27 06:00
MHDA- 2018/01/27 06:01
PMCR- 2017/12/26
CRDT- 2018/01/27 06:00
PHST- 2017/10/02 00:00 [received]
PHST- 2017/12/24 00:00 [accepted]
PHST- 2018/01/27 06:00 [entrez]
PHST- 2018/01/27 06:00 [pubmed]
PHST- 2018/01/27 06:01 [medline]
PHST- 2017/12/26 00:00 [pmc-release]
AID - ofx274 [pii]
AID - 10.1093/ofid/ofx274 [doi]
PST - epublish
SO  - Open Forum Infect Dis. 2017 Dec 26;5(1):ofx274. doi: 10.1093/ofid/ofx274. 
      eCollection 2018 Jan.