PMID- 29372777
OWN - NLM
STAT- MEDLINE
DCOM- 20181004
LR  - 20181004
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 35
IP  - 12
DP  - 2017 Dec 8
TI  - [Determination of 64 veterinary drug residues in aquatic products by ultra-high 
      performance liquid chromatography-quadrupole/electrostatic field orbitrap 
      high-resolution mass spectrometry].
PG  - 1266-1275
LID - 10.3724/SP.J.1123.2017.08021 [doi]
AB  - A method has been developed for the simultaneous determination of 64 veterinary 
      drugs in aquatic products using ultra-high performance liquid 
      chromatography-quadrupole/electrostatic field orbitrap high-resolution mass 
      spectrometry. The samples were extracted with an acetonitrile/water mixture 
      (80/20, v/v), cleaned up by normal hexane saturated with acetonitrile and primary 
      secondary amine (PSA) adsorbent, quantified with external standard method. The 
      drugs were analyzed in full scan/data dependent mass spectrum 2 (Full MS/ddMS(2)) 
      Top 1 mode. The calibration curves of the 64 drugs were linear with the 
      correlation coefficients more than 0. 9967. The average recoveries of the 64 
      analytes ranged from 56.2% to 124.6%, and the relative standard deviations (RSDs) 
      were 1.3%-29.8% in the three kinds of matrixes (fish, shrimp and shell) at three 
      levels. The limits of quantification were 0.2-10 mug/kg. The method is simple, 
      rapid, sensitive, reliable and suitable for the screening of residues in aquatic 
      products.
FAU - Li, Rong
AU  - Li R
AD  - Inspection and Quarantine Technology Center, Zhongshan Entry-Exit Inspection and 
      Quarantine Bureau, Zhongshan 528400, China. lirong828@126.com.
FAU - Yang, Luqi
AU  - Yang L
AD  - Inspection and Quarantine Technology Center, Zhongshan Entry-Exit Inspection and 
      Quarantine Bureau, Zhongshan 528400, China.
AD  - School of Food Science, Guangdong Pharmaceutical University, Zhongshan 528458, 
      China.
FAU - Zhang, Pengyun
AU  - Zhang P
AD  - Inspection and Quarantine Technology Center, Zhongshan Entry-Exit Inspection and 
      Quarantine Bureau, Zhongshan 528400, China.
FAU - Luo, Yangdan
AU  - Luo Y
AD  - Inspection and Quarantine Technology Center, Zhongshan Entry-Exit Inspection and 
      Quarantine Bureau, Zhongshan 528400, China.
FAU - Zhang, Pengjie
AU  - Zhang P
AD  - Inspection and Quarantine Technology Center, Zhongshan Entry-Exit Inspection and 
      Quarantine Bureau, Zhongshan 528400, China.
FAU - Gao, Yongqing
AU  - Gao Y
AD  - School of Food Science, Guangdong Pharmaceutical University, Zhongshan 528458, 
      China. yongqingg@163.com.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Veterinary Drugs)
SB  - IM
MH  - Animals
MH  - Chromatography, High Pressure Liquid
MH  - Drug Residues/*analysis
MH  - Fishes
MH  - *Food Contamination
MH  - Seafood/*analysis
MH  - Tandem Mass Spectrometry
MH  - Veterinary Drugs/*analysis
OTO - NOTNLM
OT  - aquatic products
OT  - high-resolution mass spectrometry (HRMS)
OT  - residue
OT  - ultra-high performance liquid chromatography (UHPLC)
OT  - veterinary drug
EDAT- 2018/01/27 06:00
MHDA- 2018/10/05 06:00
CRDT- 2018/01/27 06:00
PHST- 2018/01/27 06:00 [entrez]
PHST- 2018/01/27 06:00 [pubmed]
PHST- 2018/10/05 06:00 [medline]
AID - 10.3724/SP.J.1123.2017.08021 [doi]
PST - ppublish
SO  - Se Pu. 2017 Dec 8;35(12):1266-1275. doi: 10.3724/SP.J.1123.2017.08021.