PMID- 29379232
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220311
IS  - 0971-3026 (Print)
IS  - 1998-3808 (Electronic)
IS  - 0970-2016 (Linking)
VI  - 27
IP  - 4
DP  - 2017 Oct-Dec
TI  - Appraisal of radiation dose with 64-slice computed tomography perfusion in lung 
      cancer patients with special reference to SSDE: An initial experience in a 
      tertiary care hospital.
PG  - 389-396
LID - 10.4103/ijri.IJRI_44_17 [doi]
AB  - CONTEXT: Computed tomography perfusion (CTP) is an important functional tool for 
      lung cancer. It is expected to deliver high radiation dose, making its accurate 
      estimation important. Size-specific dose estimate (SSDE) is a new dose metric, 
      which includes the scanner output as well as the patient size. AIMS: To determine 
      radiation dose [CT dose index (CTDI(vol)), dose length product (DLP), effective 
      dose (ED), and SSDE] for CTP in lung cancer and the correlation of CTDI(vol), 
      DLP, and SSDE with effective diameter and SSDE with weight, body mass index 
      (BMI), and the scan length. SETTINGS AND DESIGN: Cross-sectional study in the 
      Department of Radio-diagnosis from October 2015 to March 2016. PATIENTS AND 
      METHODS: Due ethical approval and informed consent was taken. Thirty consecutive 
      adult patients of lung cancer undergoing CTP study were included; various 
      radiation dose parameters were determined and presented as mean +/- SD. STATISTICAL 
      ANALYSIS USED: Paired Student's t-test and Pearson correlation using Statistical 
      Package for the Social Sciences, Version 16. RESULTS: Mean radiation dose was 
      CTDI(vol) = 270.138 +/- 1.627 mGy, DLP = 681 +/- 53.496 mGy.cm, ED = 12.501 +/- 0.923 
      mSv, SSDE = 388.90 +/- 81.27 mGy. The CTDI(vol) and DLP had significant positive 
      correlation (r = 0.556, P = 0.000 and r = 0.522, P = 0.003, respectively) with 
      effective diameter. SSDE had strong negative correlation (r = -0.997, P = 0.000) 
      with effective diameter, significant negative correlation with the BMI (r = 
      -0.889; P = 0.000) and weight (r = -0.910, P = 0.000) of patients. Scan length 
      was not significantly correlated in SSDE (r = -0.012, P = 0.951). CONCLUSIONS: 
      Smaller sized patients had greater SSDE.
FAU - Bhatt, Shuchi
AU  - Bhatt S
AD  - Department of Radio-diagnosis, University College of Medical Sciences and Guru 
      Teg Bahadur Hospital, New Delhi, India.
FAU - Srivastava, Ajai K
AU  - Srivastava AK
AD  - Department of Radio-diagnosis, University College of Medical Sciences and Guru 
      Teg Bahadur Hospital, New Delhi, India.
FAU - Meena, Neha
AU  - Meena N
AD  - Department of Radio-diagnosis, University College of Medical Sciences and Guru 
      Teg Bahadur Hospital, New Delhi, India.
FAU - Thakur, Shweta
AU  - Thakur S
AD  - Department of Radio-diagnosis, Post Graduate Institute of Medical Education and 
      Research, Chandigarh, India.
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Indian J Radiol Imaging
JT  - The Indian journal of radiology & imaging
JID - 8503873
PMC - PMC5761164
OTO - NOTNLM
OT  - Lung cancer
OT  - multidetector computed tomography
OT  - patient safety
OT  - perfusion imaging
OT  - radiometry
COIS- There are no conflicts of interest.
EDAT- 2018/01/31 06:00
MHDA- 2018/01/31 06:01
PMCR- 2017/10/01
CRDT- 2018/01/31 06:00
PHST- 2018/01/31 06:00 [entrez]
PHST- 2018/01/31 06:00 [pubmed]
PHST- 2018/01/31 06:01 [medline]
PHST- 2017/10/01 00:00 [pmc-release]
AID - IJRI-27-389 [pii]
AID - 10.4103/ijri.IJRI_44_17 [doi]
PST - ppublish
SO  - Indian J Radiol Imaging. 2017 Oct-Dec;27(4):389-396. doi: 
      10.4103/ijri.IJRI_44_17.