PMID- 29379748
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220311
IS  - 2215-0013 (Print)
IS  - 2215-0013 (Electronic)
IS  - 2215-0013 (Linking)
VI  - 1
IP  - 3
DP  - 2014 Sep
TI  - Cognitive functioning among patients with schizophrenia in a Nigerian hospital: a 
      comparison with mood disorder.
PG  - 155-159
LID - 10.1016/j.scog.2014.08.003 [doi]
AB  - OBJECTIVE: The study aimed to investigate correlates of cognition among patients 
      with schizophrenia. METHODS: Over a three month period, in-patients diagnosed 
      with schizophrenia (n = 50) and mood disorders (n = 50) were recruited into the 
      study. Both groups of patients were assessed using the Schedules for Clinical 
      Assessment in Neuropsychiatry (SCAN), the Annett Hand Preference Questionnaire 
      (AHPQ) and the Global Assessment of Function Scale (GAF). Patients with 
      schizophrenia were further assessed using the Positive and Negative Syndromes 
      Scale, PANSS and the Clinical Global impression (CGI). The cognitive screen 
      section of SCAN (comprising Verbal Trails Test and Mini Mental State examination, 
      MMSE) and the cognitive factor of PANSS were used to assess cognitive function. 
      RESULTS: No differences were found in the cognitive profile of patients with 
      schizophrenia and mood disorder. Among patients with schizophrenia, poor verbal 
      performance was associated with the negative or mixed syndrome (p = 0.004), left 
      or mixed handedness (p = 0.013), greater illness severity (p = 0.030) and lower 
      GAF scores (p = 0.039). Poor performance on MMSE correlated with higher total 
      PANSS score (p = 0.022) and was also associated with the negative or mixed 
      syndrome (p = 0.003) and lack of clinical improvement (p = 0.035). CONCLUSION: 
      Patients with the negative or mixed schizophrenia syndrome may suffer more 
      cognitive deficit. Poor verbal performance among patients with schizophrenia may 
      be associated with left or mixed handedness, more severe illness and poor 
      functioning.
FAU - Okewole, Adeniran Olubunmi
AU  - Okewole AO
AD  - Neuropsychiatric Hospital, Abeokuta, Nigeria.
FAU - Adewuya, Abiodun Olugbenga
AU  - Adewuya AO
AD  - Lagos State University College of Medicine, Lagos, Nigeria.
FAU - Makanjuola, Roger Olatokunbo Aderibigbe
AU  - Makanjuola ROA
AD  - Obafemi Awolowo University, Ife, Nigeria.
LA  - eng
PT  - Journal Article
DEP - 20141012
PL  - United States
TA  - Schizophr Res Cogn
JT  - Schizophrenia research. Cognition
JID - 101632223
PMC - PMC5779103
OTO - NOTNLM
OT  - Cognition
OT  - Functioning
OT  - Negative symptoms
OT  - Schizophrenia
EDAT- 2014/10/12 00:00
MHDA- 2014/10/12 00:01
PMCR- 2014/10/12
CRDT- 2018/01/31 06:00
PHST- 2014/07/03 00:00 [received]
PHST- 2014/08/20 00:00 [revised]
PHST- 2014/08/29 00:00 [accepted]
PHST- 2018/01/31 06:00 [entrez]
PHST- 2014/10/12 00:00 [pubmed]
PHST- 2014/10/12 00:01 [medline]
PHST- 2014/10/12 00:00 [pmc-release]
AID - S2215-0013(14)00024-9 [pii]
AID - 10.1016/j.scog.2014.08.003 [doi]
PST - epublish
SO  - Schizophr Res Cogn. 2014 Oct 12;1(3):155-159. doi: 10.1016/j.scog.2014.08.003. 
      eCollection 2014 Sep.