PMID- 29382142 OWN - NLM STAT- MEDLINE DCOM- 20180920 LR - 20181113 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 10 IP - 2 DP - 2018 Jan 29 TI - The Influence of Pre-Exercise Glucose versus Fructose Ingestion on Subsequent Postprandial Lipemia. LID - 10.3390/nu10020149 [doi] LID - 149 AB - Ingestion of low glycemic index (LGI) carbohydrate (CHO) before exercise induced less insulin response and higher fat oxidation than that of high GI (HGI) CHO during subsequent exercise. However, the effect on the subsequent postprandial lipid profile is still unclear. Therefore, the aim of this study was to investigate ingestion of CHO drinks with different GI using fructose and glucose before endurance exercise on the subsequent postprandial lipid profile. Eight healthy active males completed two experimental trials in randomized double-blind cross-over design. All participants ingested 500 mL CHO (75 g) solution either fructose (F) or glucose (G) before running on the treadmill at 60% VO(2)max for 1 h. Participants were asked to take an oral fat tolerance test (OFTT) immediately after the exercise. Blood samples were obtained for plasma and serum analysis. The F trial was significantly lower than the G trial in TG total area under the curve (AUC; 9.97 +/- 3.64 vs. 10.91 +/- 3.56 mmol x 6 h/L; p = 0.033) and incremental AUC (6.57 +/- 2.46 vs. 7.14 +/- 2.64 mmol/L x 6 h, p = 0.004). The current data suggested that a pre-exercise fructose drink showed a lower postprandial lipemia than a glucose drink after the subsequent high-fat meal. FAU - Yang, Tsung-Jen AU - Yang TJ AD - Department of Physical Education, National Taiwan Normal University, Taipei 106, Taiwan. andy32437@yahoo.com.tw. FAU - Chiu, Chih-Hui AU - Chiu CH AD - Graduate Program in Department of Exercise Health Science, National Taiwan University of Sport, Taichung 404, Taiwan. loveshalom@hotmail.com. FAU - Tseng, Mei-Hui AU - Tseng MH AD - Sport Science Research Center, National Taiwan University of Sport, Taichung 404, Taiwan. tsengmh2009@gmail.com. FAU - Chang, Cheng-Kang AU - Chang CK AUID- ORCID: 0000-0001-8335-6595 AD - Sport Science Research Center, National Taiwan University of Sport, Taichung 404, Taiwan. wspahn@seed.net.tw. FAU - Wu, Ching-Lin AU - Wu CL AD - Graduate Institute of Sports and Health Management, National Chung Hsing University, Taichung 402, Taiwan. psclw@dragon.nchu.edu.com. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20180129 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 RN - 0 (Blood Glucose) RN - 0 (Fatty Acids, Nonesterified) RN - 0 (Insulin) RN - 0 (Triglycerides) RN - 30237-26-4 (Fructose) RN - 97C5T2UQ7J (Cholesterol) RN - IY9XDZ35W2 (Glucose) RN - PDC6A3C0OX (Glycerol) SB - IM MH - Blood Glucose/metabolism MH - Cholesterol/blood MH - Cross-Over Studies MH - Double-Blind Method MH - *Exercise MH - Exercise Test MH - Fatty Acids, Nonesterified/blood MH - Fructose/*administration & dosage MH - Glucose/*administration & dosage MH - Glycemic Index MH - Glycerol/blood MH - Humans MH - Hyperlipidemias/*blood MH - Insulin/blood MH - Male MH - Meals MH - Oxygen Consumption MH - *Postprandial Period MH - Triglycerides/blood MH - Young Adult PMC - PMC5852725 OTO - NOTNLM OT - fat oxidation OT - glycemic index OT - high-density lipoprotein OT - oral fat tolerance test OT - triacylglycerol COIS- The authors declare no conflict of interest. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results. EDAT- 2018/02/01 06:00 MHDA- 2018/09/21 06:00 PMCR- 2018/02/01 CRDT- 2018/02/01 06:00 PHST- 2017/11/29 00:00 [received] PHST- 2018/01/25 00:00 [revised] PHST- 2018/01/25 00:00 [accepted] PHST- 2018/02/01 06:00 [entrez] PHST- 2018/02/01 06:00 [pubmed] PHST- 2018/09/21 06:00 [medline] PHST- 2018/02/01 00:00 [pmc-release] AID - nu10020149 [pii] AID - nutrients-10-00149 [pii] AID - 10.3390/nu10020149 [doi] PST - epublish SO - Nutrients. 2018 Jan 29;10(2):149. doi: 10.3390/nu10020149.