PMID- 29383892
OWN - NLM
STAT- MEDLINE
DCOM- 20190403
LR  - 20220330
IS  - 1000-0607 (Print)
IS  - 1000-0607 (Linking)
VI  - 43
IP  - 1
DP  - 2018 Jan 25
TI  - [Effect of Warm Acupuncture on the Levels of Serum Immunoglobulin E, 
      Interleukin-1 beta and Tumor Necrosis Factor-alpha in Rats with Allergic Rhinitis].
PG  - 35-8
LID - 10.13702/j.1000-0607.170064 [doi]
AB  - OBJECTIVE: To observe the effect of warm acupuncture on behavior and contents of 
      serum immunoglobulin E(IgE), interleukin-1 beta(IL-1 beta) and tumor necrosis 
      factor-alpha(TNF-alpha) in allergic rhinitis(AR) rats, so as to explore its mechanism 
      underlying improving AR. METHODS: Forty Wistar rats were randomly divided into 
      four groups: control group, model group, medication group and warm acupuncture 
      group(10 rats/group). The AR model was established by intraperitoneal injection 
      of sensitization and nasal drip. The rats in the medication group were given 
      fluticasone propionate nasal spray, daily for 10 days. Warm acupuncture was 
      applied to "Fengchi"(GB 20), "Yintang"(GV 29), "Yingxiang"(LI 20) for 60 seconds, 
      once daily for 10 days. Behavioral scores were used to evaluate behavioral 
      changes in rats. Enzyme linked immunosorbent assay (ELISA) was used to detect the 
      expression levels of serum IgE, IL-1 beta and TNF-alpha. RESULTS: Behavioral scores of 
      the model group were significantly higher than those of the control group 0, 3, 7 
      and 10 days after modeling (P<0.05). After treatment, the behavioral scores of 
      medication group and the warm acupuncture group were lower than those of the 
      model group (P<0.05), and the score was more lower in the warm acupuncture group 
      than in the medication group (P<0.05). Compared with the control group, the 
      levels of serum IgE, IL-1 beta and TNF-alpha in the model group were all increased 
      (P<0.01), while the levels of serum IgE, IL-1 beta and TNF-alpha were decreased in the 
      medication and warm acupuncture groups after treatment in comparison with the 
      model group (P<0.05, P<0.01). Compared with the medication group, the levels of 
      serum IgE, IL-1 beta and TNF-alpha were significantly lower in the warm acupuncture 
      group (P<0.05, P<0.01). CONCLUSION: The expression levels of IgE, IL-1 beta and 
      TNF-alpha were elevated in serum after AR attack. Warm acupuncture can improve the 
      symptoms of AR rats, which may be associated to its effect in inhibiting the 
      expression of serum IgE, IL-1 beta and TNF-alpha.
FAU - Zheng, Xian-Li
AU  - Zheng XL
AD  - Acupuncture Clinical Center, Affiliated Hospital of Gansu University of Chinese 
      Medicine, Lanzhou 730000, China.
FAU - Tian, Yong-Ping
AU  - Tian YP
AD  - Acupuncture Clinical Center, Affiliated Hospital of Gansu University of Chinese 
      Medicine, Lanzhou 730000, China.
FAU - Luo, Hai-Yan
AU  - Luo HY
AD  - Acupuncture Clinical Center, Affiliated Hospital of Gansu University of Chinese 
      Medicine, Lanzhou 730000, China.
FAU - Zhao, Yao-Dong
AU  - Zhao YD
AD  - Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China.
FAU - Liu, Xiang-Yi
AU  - Liu XY
AD  - Acupuncture Clinical Center, Affiliated Hospital of Gansu University of Chinese 
      Medicine, Lanzhou 730000, China.
FAU - Jiang, Ying
AU  - Jiang Y
AD  - Acupuncture Clinical Center, Affiliated Hospital of Gansu University of Chinese 
      Medicine, Lanzhou 730000, China.
FAU - Ma, Cheng-Xu
AU  - Ma CX
AD  - Acupuncture Clinical Center, Affiliated Hospital of Gansu University of Chinese 
      Medicine, Lanzhou 730000, China.
FAU - Wang, Ming-Juan
AU  - Wang MJ
AD  - Acupuncture Clinical Center, Affiliated Hospital of Gansu University of Chinese 
      Medicine, Lanzhou 730000, China.
FAU - Liu, Min
AU  - Liu M
AD  - Acupuncture Clinical Center, Affiliated Hospital of Gansu University of Chinese 
      Medicine, Lanzhou 730000, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhen Ci Yan Jiu
JT  - Zhen ci yan jiu = Acupuncture research
JID - 8507710
RN  - 0 (Interleukin-1beta)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Acupuncture Points
MH  - Animals
MH  - Immunoglobulin E
MH  - Interleukin-1beta
MH  - Rats
MH  - Rats, Wistar
MH  - *Rhinitis, Allergic
MH  - Tumor Necrosis Factor-alpha
OTO - NOTNLM
OT  - Allergic rhinitis
OT  - Behavior
OT  - Immunoglobulin E
OT  - Warm acupuncture
EDAT- 2018/02/01 06:00
MHDA- 2019/04/04 06:00
CRDT- 2018/02/01 06:00
PHST- 2018/02/01 06:00 [entrez]
PHST- 2018/02/01 06:00 [pubmed]
PHST- 2019/04/04 06:00 [medline]
AID - 10.13702/j.1000-0607.170064 [doi]
PST - ppublish
SO  - Zhen Ci Yan Jiu. 2018 Jan 25;43(1):35-8. doi: 10.13702/j.1000-0607.170064.