PMID- 29392354
OWN - NLM
STAT- MEDLINE
DCOM- 20190416
LR  - 20190416
IS  - 0724-6145 (Print)
IS  - 0724-6145 (Linking)
VI  - 164
DP  - 2018
TI  - Advances in Transcriptomics of Plants.
PG  - 161-185
LID - 10.1007/10_2017_52 [doi]
AB  - The current global population of 7.3 billion is estimated to reach 9.7 billion in 
      the year 2050. Rapid population growth is driving up global food demand. 
      Additionally, global climate change, environmental degradation, drought, emerging 
      diseases, and salty soils are the current threats to global food security. In 
      order to mitigate the adverse effects of these diverse agricultural productivity 
      constraints and enhance crop yield and stress-tolerance in plants, we need to go 
      beyond traditional and molecular plant breeding. The powerful new tools for 
      genome editing, Transcription Activator-Like Effector Nucleases (TALENs) and 
      Clustered Regulatory Interspaced Short Palindromic Repeats (CRISPR)/Cas systems 
      (CRISPR-Cas9), have been hailed as a quantum leap forward in the development of 
      stress-resistant plants. Plant breeding techniques, however, have several 
      drawbacks. Hence, identification of transcriptional regulatory elements and 
      deciphering mechanisms underlying transcriptional regulation are crucial to 
      avoiding unintended consequences in modified crop plants, which could ultimately 
      have negative impacts on human health. RNA splicing as an essential regulated 
      post-transcriptional process, alternative polyadenylation as an RNA-processing 
      mechanism, along with non-coding RNAs (microRNAs, small interfering RNAs and long 
      non-coding RNAs) have been identified as major players in gene regulation. In 
      this chapter, we highlight new findings on the essential roles of alternative 
      splicing and alternative polyadenylation in plant development and response to 
      biotic and abiotic stresses. We also discuss biogenesis and the functions of 
      microRNAs (miRNAs) and small interfering RNAs (siRNAs) in plants and recent 
      advances in our knowledge of the roles of miRNAs and siRNAs in plant stress 
      response. Graphical Abstract.
FAU - Nejat, Naghmeh
AU  - Nejat N
AD  - The Pangenomics Group, School of Science, RMIT University, Melbourne, VIC, 
      Australia.
FAU - Ramalingam, Abirami
AU  - Ramalingam A
AD  - The Pangenomics Group, School of Science, RMIT University, Melbourne, VIC, 
      Australia.
FAU - Mantri, Nitin
AU  - Mantri N
AD  - The Pangenomics Group, School of Science, RMIT University, Melbourne, VIC, 
      Australia. nitin.mantri@rmit.edu.au.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Germany
TA  - Adv Biochem Eng Biotechnol
JT  - Advances in biochemical engineering/biotechnology
JID - 8307733
RN  - 0 (MicroRNAs)
RN  - 0 (RNA, Small Interfering)
SB  - IM
MH  - Gene Editing
MH  - *Gene Expression Profiling/trends
MH  - MicroRNAs/genetics
MH  - Plant Breeding
MH  - *Plants/genetics
MH  - RNA, Small Interfering
MH  - Stress, Physiological/genetics
OTO - NOTNLM
OT  - Abiotic stress
OT  - Alternative polyadenylation
OT  - Alternative splicing
OT  - Biotic stress
OT  - Small interfering RNAs
OT  - microRNAs
EDAT- 2018/02/03 06:00
MHDA- 2019/04/17 06:00
CRDT- 2018/02/03 06:00
PHST- 2018/02/03 06:00 [pubmed]
PHST- 2019/04/17 06:00 [medline]
PHST- 2018/02/03 06:00 [entrez]
AID - 10.1007/10_2017_52 [doi]
PST - ppublish
SO  - Adv Biochem Eng Biotechnol. 2018;164:161-185. doi: 10.1007/10_2017_52.