PMID- 29399576 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200929 IS - 2287-3651 (Print) IS - 2287-366X (Electronic) IS - 2287-3651 (Linking) VI - 7 IP - 1 DP - 2018 Jan TI - Distinct features of dendritic cell-based immunotherapy as cancer vaccines. PG - 16-23 LID - 10.7774/cevr.2018.7.1.16 [doi] AB - Dendritic cells (DCs) are the most professional antigen presenting cells that play important roles in connection between innate and adaptive immune responses. Numerous studies revealed that the functions of DCs are related with the capture and processing of antigen as well as the migration to lymphoid tissues for the presenting antigens to T cells. These unique features of DCs allow them to be considered as therapeutic vaccines that can induce immune responses and anti-tumor activity. Here, we discuss and understand the immunological basis of DCs and presume the possibilities of DC-based vaccines for the promising cancer therapy. FAU - Lee, Chaelin AU - Lee C AUID- ORCID: 0000-0002-8992-3287 AD - Department of Bioscience & Biotechnology, Sejong University, Seoul, Korea. FAU - Lee, Myungmi AU - Lee M AUID- ORCID: 0000-0001-7803-8242 AD - Department of Bioscience & Biotechnology, Sejong University, Seoul, Korea. FAU - Rhee, Inmoo AU - Rhee I AUID- ORCID: 0000-0001-5272-712X AD - Department of Bioscience & Biotechnology, Sejong University, Seoul, Korea. LA - eng PT - Journal Article PT - Review DEP - 20180129 PL - Korea (South) TA - Clin Exp Vaccine Res JT - Clinical and experimental vaccine research JID - 101592344 PMC - PMC5795041 OTO - NOTNLM OT - Dendritic cells OT - Immunotherapy OT - Neoplasms OT - Vaccines COIS- No potential conflict of interest relevant to this article was reported. EDAT- 2018/02/06 06:00 MHDA- 2018/02/06 06:01 PMCR- 2018/01/01 CRDT- 2018/02/06 06:00 PHST- 2017/11/25 00:00 [received] PHST- 2017/12/22 00:00 [revised] PHST- 2017/12/28 00:00 [accepted] PHST- 2018/02/06 06:00 [entrez] PHST- 2018/02/06 06:00 [pubmed] PHST- 2018/02/06 06:01 [medline] PHST- 2018/01/01 00:00 [pmc-release] AID - 10.7774/cevr.2018.7.1.16 [doi] PST - ppublish SO - Clin Exp Vaccine Res. 2018 Jan;7(1):16-23. doi: 10.7774/cevr.2018.7.1.16. Epub 2018 Jan 29.