PMID- 29399899 OWN - NLM STAT- MEDLINE DCOM- 20180319 LR - 20180319 IS - 1540-8191 (Electronic) IS - 0886-0440 (Linking) VI - 33 IP - 2 DP - 2018 Feb TI - Short- and long-term outcomes following redo valvular surgery. PG - 56-63 LID - 10.1111/jocs.13534 [doi] AB - AIM: We reviewed our experience in redo valvular surgery to evaluate trends in short- and long-term outcomes. METHODS: We reviewed 414 patients (mean age, 62.8 +/- 13.6 years) who underwent redo valvular surgery in the past 25 years. A total of 301 patients (54.2%) underwent first-time redo valvular surgeries; 178 (32.1%) were second redos, 60 (10.8%) were third redos, and 16 were fourth redos (2.9%). The mean follow-up period was 6.8 +/- 6.3 years. RESULTS: Hospital mortality was 5.8%. New York Heart Association (NYHA) class III/IV (P = 0.0007, odds ratio = 4.403) and hemodialysis (P = 0.0383, odds ratio = 7.196) were risk factors for hospital death. Long-term survival rates at 15 and 20 years were 64.7% +/- 4.3% and 59.1% +/- 5.0%, respectively. Predictors of late death were first time redo (P = 0.0076, hazard ratio = 0.422) and age younger than 61 years (P = 0.0005, hazard ratio = 0.229). There were significant differences in long-term survival between NYHA classes I/II and III/IV (log-rank test, P = 0.0419) and between the time from redo surgery (log-rank test, P = 0.0189) and age (log-rank test, P = 0.0001). CONCLUSIONS: The hospital mortality rate for redo valve surgery has improved. Early referral for redo surgery can contribute to improving early and late outcomes. CI - (c) 2018 Wiley Periodicals, Inc. FAU - Fukunaga, Naoto AU - Fukunaga N AUID- ORCID: 0000-0002-5954-3451 AD - Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Japan. FAU - Sakata, Ryuzo AU - Sakata R AD - Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Japan. FAU - Koyama, Tadaaki AU - Koyama T AD - Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Japan. LA - eng PT - Journal Article DEP - 20180204 PL - United States TA - J Card Surg JT - Journal of cardiac surgery JID - 8908809 SB - IM MH - Aged MH - Aged, 80 and over MH - Cardiac Valve Annuloplasty MH - Female MH - Follow-Up Studies MH - Heart Valve Diseases/*surgery MH - *Heart Valve Prosthesis Implantation MH - Heart Valves/*surgery MH - Hospital Mortality MH - Humans MH - Male MH - Middle Aged MH - *Reoperation/statistics & numerical data MH - Retrospective Studies MH - Risk Factors MH - Survival Rate MH - Time Factors MH - Treatment Outcome OTO - NOTNLM OT - 25 years of experience OT - redo valvular surgery EDAT- 2018/02/06 06:00 MHDA- 2018/03/20 06:00 CRDT- 2018/02/06 06:00 PHST- 2018/02/06 06:00 [pubmed] PHST- 2018/03/20 06:00 [medline] PHST- 2018/02/06 06:00 [entrez] AID - 10.1111/jocs.13534 [doi] PST - ppublish SO - J Card Surg. 2018 Feb;33(2):56-63. doi: 10.1111/jocs.13534. Epub 2018 Feb 4.