PMID- 29400584
OWN - NLM
STAT- MEDLINE
DCOM- 20190821
LR  - 20190821
IS  - 2169-141X (Electronic)
IS  - 2169-1401 (Linking)
VI  - 46
IP  - sup1
DP  - 2018
TI  - Biosynthesis of pure hematite phase magnetic iron oxide nanoparticles using 
      floral extracts of Callistemon viminalis (bottlebrush): their physical properties 
      and novel biological applications.
PG  - 693-707
LID - 10.1080/21691401.2018.1434534 [doi]
AB  - Aqueous floral extracts of Callistemon viminalis were used to synthesize 
      Fe(2)O(3) nanoparticles (IONPs) which were intensively characterized through 
      UV-vis, X-ray diffraction, HR-SEM/HR-TEM, Fourier- transform infrared 
      spectroscopy (FTIR) and energy dispersive X-ray spectroscopy (EDS). Their 
      physical properties were studied in response to different annealing temperatures. 
      It was observed that the increase in the annealing temperature produced 
      small-sized nanoparticles. The nanoparticle size was calculated as 32, 26 and 
      22 nm for annealing at 300, 400 and 500  degrees C, respectively. The magnetic nature of 
      the bioinspired IONPs was revealed by superconducting quantum interference device 
      (SQUID). Their antibacterial potential was investigated against nine pathogenic 
      bacterial strains (gram positive and gram negative) using disc diffusion method 
      while their MIC was calculated using broth dilution assay. Bioinspired IONPs were 
      found to be highly effective against HepG2 cells (IC(50)=20 microg/mL). Moderate 
      antileishmanial activities against the promastigotes and amastigotes cultures are 
      reported. Moderate acetylcholine esterase (AchE), butylcholine esterase (BchE) 
      and alpha-Glycosidase inhibition are reported. Additional assessment of the 
      biocompatibility was performed using haemolytic activity on the freshly isolated 
      human red blood cells and macrophages. Furthermore, the antioxidant activities, 
      including TAC, DPPH and TRP were also performed. Our results indicate that the 
      biogenic and magnetic Fe(2)O(3) can be used for diverse biomedical applications.
FAU - Hassan, Dilawar
AU  - Hassan D
AD  - a Preston Institute of Nanoscience and Nanotechnology (PINSAT), Preston 
      University , Islamabad , Pakistan.
AD  - b UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology , College of 
      Graduate Studies, University of South Africa , Pretoria , South Africa.
AD  - c Nanosciences African Network (NANOAFNET) , iThemba LABS-National Research 
      Foundation, Somerset West , South Africa.
FAU - Khalil, Ali Talha
AU  - Khalil AT
AD  - b UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology , College of 
      Graduate Studies, University of South Africa , Pretoria , South Africa.
AD  - c Nanosciences African Network (NANOAFNET) , iThemba LABS-National Research 
      Foundation, Somerset West , South Africa.
AD  - d Department of Eastern Medicine and Surgery , Qarshi University , Lahore , 
      Pakistan.
FAU - Saleem, Jabran
AU  - Saleem J
AD  - a Preston Institute of Nanoscience and Nanotechnology (PINSAT), Preston 
      University , Islamabad , Pakistan.
FAU - Diallo, Abdullah
AU  - Diallo A
AD  - b UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology , College of 
      Graduate Studies, University of South Africa , Pretoria , South Africa.
AD  - c Nanosciences African Network (NANOAFNET) , iThemba LABS-National Research 
      Foundation, Somerset West , South Africa.
FAU - Khamlich, Saleh
AU  - Khamlich S
AD  - b UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology , College of 
      Graduate Studies, University of South Africa , Pretoria , South Africa.
AD  - c Nanosciences African Network (NANOAFNET) , iThemba LABS-National Research 
      Foundation, Somerset West , South Africa.
FAU - Shinwari, Zabta Khan
AU  - Shinwari ZK
AD  - d Department of Eastern Medicine and Surgery , Qarshi University , Lahore , 
      Pakistan.
AD  - e Pakistan Academy of Sciences , Islamabad , Pakistan.
FAU - Maaza, Malik
AU  - Maaza M
AD  - b UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology , College of 
      Graduate Studies, University of South Africa , Pretoria , South Africa.
AD  - c Nanosciences African Network (NANOAFNET) , iThemba LABS-National Research 
      Foundation, Somerset West , South Africa.
LA  - eng
PT  - Journal Article
DEP - 20180205
PL  - England
TA  - Artif Cells Nanomed Biotechnol
JT  - Artificial cells, nanomedicine, and biotechnology
JID - 101594777
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Antineoplastic Agents)
RN  - 0 (Antioxidants)
RN  - 0 (Antiprotozoal Agents)
RN  - 0 (Cholinesterase Inhibitors)
RN  - 0 (Ferric Compounds)
RN  - 0 (Plant Extracts)
RN  - 1K09F3G675 (ferric oxide)
MH  - Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology
MH  - Antineoplastic Agents/chemical synthesis/chemistry/pharmacology
MH  - Antioxidants/chemical synthesis/chemistry/pharmacology
MH  - Antiprotozoal Agents/chemical synthesis/chemistry/pharmacology
MH  - Chemistry Techniques, Synthetic
MH  - Cholinesterase Inhibitors/chemical synthesis/chemistry/pharmacology
MH  - Erythrocytes/cytology/drug effects
MH  - Ferric Compounds/*chemical synthesis/chemistry/*pharmacology
MH  - Flowers/*chemistry
MH  - Hep G2 Cells
MH  - Humans
MH  - Magnets/*chemistry
MH  - Materials Testing
MH  - Myrtaceae/*chemistry
MH  - Particle Size
MH  - *Physical Phenomena
MH  - Plant Extracts/*chemistry
MH  - Temperature
OTO - NOTNLM
OT  - DPPH
OT  - HepG2
OT  - Iron oxide (FeO)
OT  - anti-cancer
OT  - antibacterial
OT  - antileishmanial
OT  - biocompatibility
OT  - hematite
OT  - hepatocellular carcinoma
OT  - magnetic
OT  - nanoparticles
OT  - temperature
EDAT- 2018/02/06 06:00
MHDA- 2019/08/23 06:00
CRDT- 2018/02/06 06:00
PHST- 2018/02/06 06:00 [pubmed]
PHST- 2019/08/23 06:00 [medline]
PHST- 2018/02/06 06:00 [entrez]
AID - 10.1080/21691401.2018.1434534 [doi]
PST - ppublish
SO  - Artif Cells Nanomed Biotechnol. 2018;46(sup1):693-707. doi: 
      10.1080/21691401.2018.1434534. Epub 2018 Feb 5.