PMID- 29405556
OWN - NLM
STAT- MEDLINE
DCOM- 20191125
LR  - 20191125
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 92
IP  - 5
DP  - 2018 Nov 1
TI  - Heparin use for diagnostic cardiac catheterization with a radial artery approach: 
      An international survey of practice patterns.
PG  - 854-859
LID - 10.1002/ccd.27530 [doi]
AB  - OBJECTIVES: We aimed to describe global practice patterns of unfractionated 
      heparin (UFH) use for diagnostic transradial cardiac catheterization. BACKGROUND: 
      The use of the radial artery approach for cardiac catheterization is increasing 
      globally. Limited contemporary data exist to support the use or optimal dosing of 
      UFH to prevent radial artery occlusion (RAO) and other thromboembolic 
      complications. METHODS: We performed a web-based international survey of 450 
      interventional cardiologists from 34 countries. We collected information 
      regarding the experience and use of UFH for diagnostic transradial cardiac 
      catheterization. RESULTS: The survey was conducted between June and July 2016 and 
      was completed by 227 (50.4%) interventional cardiologists. Overall, 83.3% 
      performed >75% of their coronary angiograms via a radial approach, with the 
      plurality (41.9%) having 10-20 years of clinical experience. Of all respondents, 
      7.5% did not use UFH for routine diagnostic transradial heart catheterization. Of 
      the 92.5% who did use UFH, it was preferentially administered intra-arterially by 
      60% and intravenously by 40%. The majority (62.6%) of interventionalists used a 
      fixed UFH dose with 5,000 IU being the most common dose (used in 48%). For those 
      using a weight-based UFH (50 IU/kg) dosing regimen for diagnostic procedures 
      (36.1%), the administered UFH dose ranged from 2,000 up to 10,000 IU. 
      CONCLUSIONS: Despite the lack of firm evidence, the majority of interventional 
      cardiologists who participated in the survey use UFH to prevent RAO for 
      diagnostic transradial coronary angiography. However, there exist large practice 
      disparities with regards to dose and route of administration. Given this 
      knowledge gap, a dedicated randomized trial is warranted.
CI  - (c) 2018 Wiley Periodicals, Inc.
FAU - Bossard, Matthias
AU  - Bossard M
AUID- ORCID: 0000-0002-1587-2819
AD  - Division of Cardiology, Hamilton General Hospital, Hamilton Health Sciences, 
      McMaster University, Hamilton, Ontario, Canada.
AD  - Population Health Research Institute, McMaster University Hamilton Health 
      Sciences, Hamilton, Ontario, Canada.
FAU - Lavi, Shahar
AU  - Lavi S
AUID- ORCID: 0000-0002-6105-8084
AD  - Division of Cardiology, London Health Sciences Centre, Western University, 
      London, Ontario, Canada.
FAU - Rao, Sunil V
AU  - Rao SV
AD  - Duke Clinical Research Institute, Durham, North Carolina.
AD  - Division of Cardiology, Department of Medicine, Duke University School of 
      Medicine, Durham, North Carolina.
FAU - Cohen, David J
AU  - Cohen DJ
AD  - Saint Luke's Mid America Heart Institute, Kansas City, Missouri.
FAU - Cantor, Warren J
AU  - Cantor WJ
AD  - York Clinical Cardiology, Southlake Regional Health Centre, Vaughan, Ontario.
FAU - Bainey, Kevin R
AU  - Bainey KR
AD  - Division of Cardiology, Mazankowski Alberta Heart Institute, University of 
      Alberta, Edmonton, Alberta, Canada.
FAU - Valettas, Nicholas
AU  - Valettas N
AD  - Division of Cardiology, Hamilton General Hospital, Hamilton Health Sciences, 
      McMaster University, Hamilton, Ontario, Canada.
FAU - Jolly, Sanjit S
AU  - Jolly SS
AD  - Division of Cardiology, Hamilton General Hospital, Hamilton Health Sciences, 
      McMaster University, Hamilton, Ontario, Canada.
AD  - Population Health Research Institute, McMaster University Hamilton Health 
      Sciences, Hamilton, Ontario, Canada.
FAU - Mehta, Shamir R
AU  - Mehta SR
AD  - Division of Cardiology, Hamilton General Hospital, Hamilton Health Sciences, 
      McMaster University, Hamilton, Ontario, Canada.
AD  - Population Health Research Institute, McMaster University Hamilton Health 
      Sciences, Hamilton, Ontario, Canada.
LA  - eng
PT  - Journal Article
DEP - 20180206
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
RN  - 0 (Anticoagulants)
RN  - 9005-49-6 (Heparin)
SB  - IM
CIN - Catheter Cardiovasc Interv. 2018 Nov 1;92(5):860-861. PMID: 30450711
MH  - Anticoagulants/*therapeutic use
MH  - Arterial Occlusive Diseases/etiology/prevention & control
MH  - Cardiac Catheterization/adverse effects/*trends
MH  - Cardiologists/*trends
MH  - Catheterization, Peripheral/adverse effects/*trends
MH  - Coronary Angiography/adverse effects/*trends
MH  - Health Care Surveys
MH  - Heparin/*therapeutic use
MH  - Humans
MH  - Practice Patterns, Physicians'/*trends
MH  - Predictive Value of Tests
MH  - *Radial Artery
MH  - Risk Factors
MH  - Thromboembolism/etiology/prevention & control
OTO - NOTNLM
OT  - angiography
OT  - anticoagulation
OT  - heparin
OT  - radial approach
OT  - radial artery
OT  - survey
EDAT- 2018/02/07 06:00
MHDA- 2019/11/26 06:00
CRDT- 2018/02/07 06:00
PHST- 2017/05/31 00:00 [received]
PHST- 2017/12/08 00:00 [revised]
PHST- 2018/01/15 00:00 [accepted]
PHST- 2018/02/07 06:00 [pubmed]
PHST- 2019/11/26 06:00 [medline]
PHST- 2018/02/07 06:00 [entrez]
AID - 10.1002/ccd.27530 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2018 Nov 1;92(5):854-859. doi: 10.1002/ccd.27530. 
      Epub 2018 Feb 6.