PMID- 29413218 OWN - NLM STAT- MEDLINE DCOM- 20180417 LR - 20201209 IS - 1558-3481 (Electronic) IS - 0899-5885 (Linking) VI - 30 IP - 1 DP - 2018 Mar TI - Evidence-Based Practice in the Treatment for Antibiotic-Associated Diarrhea in the Intensive Care Unit. PG - 87-99 LID - S0899-5885(17)30096-5 [pii] LID - 10.1016/j.cnc.2017.10.008 [doi] AB - Unit nurses provide care to patients with serious health conditions. Often antibiotics are recommended to fight infections. Sometimes patients are on proton pump inhibitors (PPI). Antibiotics and PPIs may lead to diarrhea, causing the patient more discomfort, and possibly leading to a more serious infection. One serious infection is caused by Clostridium difficile, which causes death in some cases. About 75% of patients on antibiotics may not need antibiotics. Several studies showed less diarrhea in patients on probiotics. However, probiotics cause harm to some patients, which needs to be considered. Nurses need to ensure that antibiotic stewardship is followed. CI - Copyright (c) 2017 Elsevier Inc. All rights reserved. FAU - Squellati, Robin AU - Squellati R AD - MSN SP Program, Walden University, Minneapolis, MN, USA. Electronic address: robin.squellati@mail.waldenu.edu. LA - eng PT - Journal Article PT - Review DEP - 20171129 PL - United States TA - Crit Care Nurs Clin North Am JT - Critical care nursing clinics of North America JID - 8912620 RN - 0 (Anti-Bacterial Agents) RN - 0 (Proton Pump Inhibitors) RN - 6Q205EH1VU (Vancomycin) MH - Anti-Bacterial Agents/*therapeutic use MH - Clostridioides difficile/isolation & purification MH - Critical Care Nursing MH - Cross Infection/prevention & control MH - Diarrhea/chemically induced/*drug therapy MH - *Evidence-Based Practice MH - Humans MH - Intensive Care Units MH - Proton Pump Inhibitors/adverse effects MH - Risk Factors MH - Vancomycin/*therapeutic use OTO - NOTNLM OT - Antibiotic OT - Clostridium difficile OT - Diarrhea OT - Probiotics OT - Spores OT - Vancomycin EDAT- 2018/02/08 06:00 MHDA- 2018/04/18 06:00 CRDT- 2018/02/08 06:00 PHST- 2018/02/08 06:00 [entrez] PHST- 2018/02/08 06:00 [pubmed] PHST- 2018/04/18 06:00 [medline] AID - S0899-5885(17)30096-5 [pii] AID - 10.1016/j.cnc.2017.10.008 [doi] PST - ppublish SO - Crit Care Nurs Clin North Am. 2018 Mar;30(1):87-99. doi: 10.1016/j.cnc.2017.10.008. Epub 2017 Nov 29.