PMID- 29424233 OWN - NLM STAT- MEDLINE DCOM- 20180316 LR - 20211204 IS - 1520-5118 (Electronic) IS - 0021-8561 (Linking) VI - 66 IP - 9 DP - 2018 Mar 7 TI - Quantitation of Oleuropein and Related Phenolics in Cured Spanish-Style Green, California-Style Black Ripe, and Greek-Style Natural Fermentation Olives. PG - 2121-2128 LID - 10.1021/acs.jafc.7b06025 [doi] AB - Oleuropein, ligstroside, and related hydrolysis products are key contributors to olive bitterness, and several of these phenolics are implicated in the prevention of lifestyle age-related diseases. While table olive processing methods are designed to reduce oleuropein, the impact of processing on ligstroside and related hydrolysis products (e.g., oleacein, oleocanthal, hydroxytyrosol glucoside, ligstroside aglycone, and oleuropein aglycone) is relatively unknown. Herein, levels of these compounds were measured in Spanish-style green (SP), Californian-style black ripe (CA), and Greek-style natural fermentation (GK) olives using rapid ultrahigh-performance liquid chromatography (UHPLC) tandem mass spectrometry (MS/MS). GK olives had the highest concentration of all compounds measured, with the exception of oleocanthal, which was highest in SP olives (0.081 mg kg(-1) wet weight (w.wt)). CA olives had the lowest levels of most compounds measured, including ligstroside (0.115 mg kg(-1) w.wt) and oleuropein (0.974 mg kg(-1) w.wt). Hydroxytyrosol was the predominate compound in all three styles of commercial olives, with similar concentrations observed for GK and SP olives (134.329 and 133.685 mg kg(-1) w.wt, respectively) and significantly lower concentrations observed for CA olives (19.981 mg kg(-1) w.wt). FAU - Johnson, Rebecca AU - Johnson R AD - Department of Food Science and Technology , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States. FAU - Melliou, Eleni AU - Melliou E AD - Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy , University of Athens , Panepistimiopolis Zografou , GR-15771 Athens , Greece. FAU - Zweigenbaum, Jerry AU - Zweigenbaum J AUID- ORCID: 0000-0003-3844-737X AD - Agilent Technologies , 2850 Centerville Road , Wilmington , Delaware 19808 , United States. FAU - Mitchell, Alyson E AU - Mitchell AE AUID- ORCID: 0000-0003-0286-5238 LA - eng PT - Comparative Study PT - Journal Article DEP - 20180220 PL - United States TA - J Agric Food Chem JT - Journal of agricultural and food chemistry JID - 0374755 RN - 0 (Iridoid Glucosides) RN - 0 (Iridoids) RN - 0 (Phenols) RN - 2O4553545L (oleuropein) SB - IM MH - California MH - Chromatography, High Pressure Liquid MH - Fermentation MH - Food Handling MH - Fruit/chemistry/microbiology MH - Greece MH - Humans MH - Iridoid Glucosides MH - Iridoids/*chemistry/metabolism MH - Molecular Structure MH - Olea/*chemistry/microbiology MH - Phenols/*chemistry/metabolism MH - Spain MH - Tandem Mass Spectrometry MH - Taste OTO - NOTNLM OT - MS/MS OT - Olea europaea OT - UHPLC OT - ligstroside OT - oleacein OT - oleocanthal OT - oleuropein OT - oleuropein aglycone OT - olives OT - phenolics EDAT- 2018/02/10 06:00 MHDA- 2018/03/17 06:00 CRDT- 2018/02/10 06:00 PHST- 2018/02/10 06:00 [pubmed] PHST- 2018/03/17 06:00 [medline] PHST- 2018/02/10 06:00 [entrez] AID - 10.1021/acs.jafc.7b06025 [doi] PST - ppublish SO - J Agric Food Chem. 2018 Mar 7;66(9):2121-2128. doi: 10.1021/acs.jafc.7b06025. Epub 2018 Feb 20.