PMID- 29427677
OWN - NLM
STAT- MEDLINE
DCOM- 20180910
LR  - 20180910
IS  - 1879-0003 (Electronic)
IS  - 0141-8130 (Linking)
VI  - 112
DP  - 2018 Jun
TI  - Development of graft copolymer of carboxymethylcellulose and N-vinylcaprolactam 
      towards strong antioxidant and antibacterial polymeric materials.
PG  - 780-787
LID - S0141-8130(17)33751-0 [pii]
LID - 10.1016/j.ijbiomac.2018.02.030 [doi]
AB  - The present paper reports graft copolymerization of N-vinylcaprolactam (NVCL) 
      onto carboxymethylcellulose (CMC) using tert-butyl hydroperoxide (TBHP) initiator 
      in N(2) atmosphere. The grafting was found to be highest when concentrations of 
      CMC, NVCL and TBHP were 6.25x10(-2)gdm(-3), 10x10(-3)moldm(-3) and 
      20x10(-5)moldm(-3) respectively. The graft copolymer (CMC-g-PNVCL-1) was 
      characterized by FTIR, (1)HNMR, SEM, AFM, XRD and TGA analysis. The antioxidant 
      activity of the graft copolymer was found to be higher (3.81%) than CMC and 
      slightly less (5.47%) than the standard one (butylated hydroxytoluene, BHT). The 
      hydroxyl radical scavenging activity of graft copolymer was found to be slightly 
      less (13.69%) than CMC and more (44.20%) than the BHT. The hydrogen peroxide 
      scavenging activity of graft copolymer was observed to be less (20.42%) than CMC 
      and 53.34% less than BHT. The superoxide scavenging activity of graft copolymer 
      was greater than the both. Compared to CMC the graft copolymer has shown greater 
      antibacterial activity against S. aureus, Proteus vulgaris and S. typhi bacteria 
      and less against Klebsiellapneumonia and Salmonella typhimurium.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Kumar, Ashok
AU  - Kumar A
AD  - Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 
      221005, UP, India.
FAU - Deepak
AU  - Deepak
AD  - Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 
      221005, UP, India.
FAU - Sharma, Swati
AU  - Sharma S
AD  - Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 
      221005, UP, India.
FAU - Afgan, Shere
AU  - Afgan S
AD  - Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 
      221005, UP, India.
FAU - Kumar, Rajesh
AU  - Kumar R
AD  - Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 
      221005, UP, India. Electronic address: orajesh@bhu.ac.in.
FAU - Keshari, Anand Kumar
AU  - Keshari AK
AD  - Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu 
      University, Varanasi 221005, UP, India.
FAU - Srivastava, Ragini
AU  - Srivastava R
AD  - Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu 
      University, Varanasi 221005, UP, India.
LA  - eng
PT  - Journal Article
DEP - 20180208
PL  - Netherlands
TA  - Int J Biol Macromol
JT  - International journal of biological macromolecules
JID - 7909578
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Antioxidants)
RN  - 0 (Polymers)
RN  - 25189-83-7 (poly-N-vinylcaprolactam)
RN  - 6879X594Z8 (Caprolactam)
RN  - K679OBS311 (Carboxymethylcellulose Sodium)
SB  - IM
MH  - Anti-Bacterial Agents/*pharmacology
MH  - Antioxidants/*pharmacology
MH  - Bacteria/drug effects
MH  - Caprolactam/*analogs & derivatives/chemistry
MH  - Carboxymethylcellulose Sodium/*chemistry
MH  - Microbial Sensitivity Tests
MH  - Microscopy, Atomic Force
MH  - Polymerization
MH  - Polymers/*chemistry
MH  - Proton Magnetic Resonance Spectroscopy
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Temperature
MH  - Thermogravimetry
MH  - X-Ray Diffraction
OTO - NOTNLM
OT  - Antibacterial activity
OT  - Antioxidant
OT  - Carboxymethylcellulose
OT  - Characterization
OT  - Graft copolymer
OT  - N-Vinylcaprolactam
EDAT- 2018/02/11 06:00
MHDA- 2018/09/11 06:00
CRDT- 2018/02/11 06:00
PHST- 2017/09/28 00:00 [received]
PHST- 2018/02/05 00:00 [revised]
PHST- 2018/02/06 00:00 [accepted]
PHST- 2018/02/11 06:00 [pubmed]
PHST- 2018/09/11 06:00 [medline]
PHST- 2018/02/11 06:00 [entrez]
AID - S0141-8130(17)33751-0 [pii]
AID - 10.1016/j.ijbiomac.2018.02.030 [doi]
PST - ppublish
SO  - Int J Biol Macromol. 2018 Jun;112:780-787. doi: 10.1016/j.ijbiomac.2018.02.030. 
      Epub 2018 Feb 8.