PMID- 29428946
OWN - NLM
STAT- MEDLINE
DCOM- 20191018
LR  - 20191018
IS  - 1423-0356 (Electronic)
IS  - 0025-7931 (Linking)
VI  - 96
IP  - 6
DP  - 2018
TI  - Determination of Cardiac Output in Pulmonary Hypertension Using Impedance 
      Cardiography.
PG  - 500-506
LID - 10.1159/000486423 [doi]
AB  - BACKGROUND: Cardiac output (CO) is a prognostic factor in pulmonary hypertension 
      (PH). Right heart catheterisation using the direct Fick method or thermodilution 
      (TD) is the reference technique for CO measurement. Impedance cardiography (IPc) 
      is a known non-invasive method of measuring CO. OBJECTIVES: In our study, we 
      assume that the measurement of CO by IPc using the PHYSIOFLOW(R) system is as 
      accurate as TD or using the direct Fick method in patients with PH in group 1 or 
      group 4. METHODS: A total of 75 patients were enrolled in a prospective study 
      carried out at the hypertension reference centre of Toulouse University Hospital. 
      Right heart catheterisation was performed for the diagnosis or follow-up of the 
      disease. CO was measured using the Fick method, TD, and IPc simultaneously. A 
      Bland-Altman analysis was plotted. RESULTS: CO was 5.7 +/- 1.9 L/min as measured by 
      the Fick method, 5.4 +/- 1.5 L/min by TD, and 5.5 +/- 1.7 L/min by IPc. The bias 
      between CO measurements by IPc and the direct Fick method was 0.149 L/min (95% 
      CI, -0.298 to 0.596). The bias between CO measurements by IPc and the TD method 
      was -0.153 L/min (95% CI, -0.450 to 0.153). The correlation decreased with the 
      more extreme CO values (< 3 L/min or > 7 L/min). A few factors changed the 
      agreement between measurements (BMI or membership in group 4). CONCLUSION: To 
      conclude, this study shows that the measurement of CO by IPc in PH patients is 
      reliable compared to the direct Fick method and TD obtained by right heart 
      catheterisation. This accuracy decreases for extreme CO values.
CI  - (c) 2018 S. Karger AG, Basel.
FAU - Dupuis, Marion
AU  - Dupuis M
AD  - Department of Pulmonology, University Hospital of Toulouse, Toulouse, 
      Francedupuis.m@chu-toulouse.fr.
FAU - Noel-Savina, Elise
AU  - Noel-Savina E
AD  - Department of Pulmonology, University Hospital of Toulouse, Toulouse, France.
FAU - Prevot, Gregoire
AU  - Prevot G
AD  - Department of Pulmonology, University Hospital of Toulouse, Toulouse, France.
FAU - Tetu, Laurent
AU  - Tetu L
AD  - Department of Pulmonology, University Hospital of Toulouse, Toulouse, France.
FAU - Pillard, Fabien
AU  - Pillard F
AD  - Department of Exploration of Respiratory Function, University Hospital of 
      Toulouse, Toulouse, France.
FAU - Riviere, Daniel
AU  - Riviere D
AD  - Department of Exploration of Respiratory Function, University Hospital of 
      Toulouse, Toulouse, France.
FAU - Didier, Alain
AU  - Didier A
AD  - Department of Pulmonology, University Hospital of Toulouse, Toulouse, France.
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20180209
PL  - Switzerland
TA  - Respiration
JT  - Respiration; international review of thoracic diseases
JID - 0137356
SB  - IM
CIN - Respiration. 2018;96(6):590. PMID: 30300892
MH  - Aged
MH  - *Cardiac Output
MH  - *Cardiography, Impedance
MH  - Female
MH  - Humans
MH  - Hypertension, Pulmonary/diagnosis/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Thermodilution
OTO - NOTNLM
OT  - Cardiac output
OT  - Impedance cardiography
OT  - Pulmonary hypertension
EDAT- 2018/02/13 06:00
MHDA- 2019/10/19 06:00
CRDT- 2018/02/12 06:00
PHST- 2017/06/23 00:00 [received]
PHST- 2017/12/18 00:00 [accepted]
PHST- 2018/02/13 06:00 [pubmed]
PHST- 2019/10/19 06:00 [medline]
PHST- 2018/02/12 06:00 [entrez]
AID - 000486423 [pii]
AID - 10.1159/000486423 [doi]
PST - ppublish
SO  - Respiration. 2018;96(6):500-506. doi: 10.1159/000486423. Epub 2018 Feb 9.