PMID- 29430189
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220409
IS  - 1178-6973 (Print)
IS  - 1178-6973 (Electronic)
IS  - 1178-6973 (Linking)
VI  - 11
DP  - 2018
TI  - The correlation between CT features and glycosylated hemoglobin level in patients 
      with T2DM complicated with primary pulmonary tuberculosis.
PG  - 187-193
LID - 10.2147/IDR.S146741 [doi]
AB  - To investigate the correlation between computed tomography (CT) features and 
      glycosylated hemoglobin (HbAlc) levels in patients with type 2 diabetes mellitus 
      (T2DM) complicated with primary pulmonary tuberculosis (PTB). One hundred and 
      eighty untreated PTB patients complicated with T2DM were selected. Based on the 
      HbAlc level, the patients were divided into three groups: HbAlc level <7% (Group 
      I: 32 patients), 7%-9% (Group II: 48 patients), and >9% (Group III: 100 
      patients). The changes of CT manifestations and HbAlc were analyzed after TB and 
      T2DM treatment. In the three groups, the detection rate of large segmented leafy 
      shadow was 50%, 56.2%, and 87%; the air bronchogram sign detection rate was 
      40.6%, 47.9%, and 77%; the discovery rate of mouth-eaten cavity was 31.2%, 45.8%, 
      and 65%; thick wall cavity detection rate was 25%, 31.2%, and 52%; the rate of 
      multiple cavities was 34.3%, 50%, and 73%; and bronchial TB was found in 33.3%, 
      21.8%, and 46%, respectively. The detection rates of lesions in Group III were 
      significantly higher than in Group II and Group I (p<0.05), and this increase was 
      significant (p<0.05). After treatment, the HbAlc level reached control target 
      (<7%) among all three groups and CT absorption improvement rates were 100%, 
      72.9%, and 56% respectively. The therapeutic efficacy of group I was better than 
      group II (p<0.01), and the treatment efficacy of group II was better than group 
      III (p<0.05). CT manifestations of T2DM complicated with PTB were closely related 
      to HbAlc level. The effect is better when HbAlc level <7%. HbAlc level 
      effectively reflects the severity and therapeutic effect to a certain extent. CT 
      scan can provide some important information for clinical imaging. The above two 
      examinations can guide clinicians to formulate the appropriate diagnosis and 
      treatment in a timely manner.
FAU - Xia, Li-Li
AU  - Xia LL
AD  - Department of Endocrinology, Shanghai Tongren Hospital, Shanghai Jiao Tong 
      University School of Medicine, Shanghai, People's Republic of China.
FAU - Li, Su-Fen
AU  - Li SF
AD  - Department of Neurology, Huai'an Second People's Hospital and The Affiliated 
      Huai'an Hospital of Xuzhou Medical University, Huai'an, People's Republic of 
      China.
FAU - Shao, Kan
AU  - Shao K
AD  - Department of Endocrinology, Shanghai Tongren Hospital, Shanghai Jiao Tong 
      University School of Medicine, Shanghai, People's Republic of China.
FAU - Zhang, Xin
AU  - Zhang X
AD  - Department of Radiology, The Fourth People's Hospital of Huai'an, Huai'an, 
      People's Republic of China.
FAU - Huang, Shan
AU  - Huang S
AD  - Department of Endocrinology, Shanghai Tongren Hospital, Shanghai Jiao Tong 
      University School of Medicine, Shanghai, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20180130
PL  - New Zealand
TA  - Infect Drug Resist
JT  - Infection and drug resistance
JID - 101550216
PMC - PMC5796470
OTO - NOTNLM
OT  - CT
OT  - HbAlc
OT  - T2DM
OT  - primary pulmonary tuberculosis
COIS- Disclosure The authors report no conflicts of interest in this work.
EDAT- 2018/02/13 06:00
MHDA- 2018/02/13 06:01
PMCR- 2018/01/30
CRDT- 2018/02/13 06:00
PHST- 2018/02/13 06:00 [entrez]
PHST- 2018/02/13 06:00 [pubmed]
PHST- 2018/02/13 06:01 [medline]
PHST- 2018/01/30 00:00 [pmc-release]
AID - idr-11-187 [pii]
AID - 10.2147/IDR.S146741 [doi]
PST - epublish
SO  - Infect Drug Resist. 2018 Jan 30;11:187-193. doi: 10.2147/IDR.S146741. eCollection 
      2018.