PMID- 29434463
OWN - NLM
STAT- MEDLINE
DCOM- 20180827
LR  - 20190107
IS  - 1945-5763 (Electronic)
IS  - 1082-0744 (Print)
IS  - 1082-0744 (Linking)
VI  - 24
IP  - 1
DP  - 2018 Winter
TI  - Initial Outcomes from a Multicenter Study Utilizing the Indego Powered 
      Exoskeleton in Spinal Cord Injury.
PG  - 78-85
LID - 10.1310/sci17-00014 [doi]
AB  - Objective: To assess safety and mobility outcomes utilizing the Indego powered 
      exoskeleton in indoor and outdoor walking conditions with individuals previously 
      diagnosed with a spinal cord injury (SCI). Methods: We conducted a multicenter 
      prospective observational cohort study in outpatient clinics associated with 5 
      rehabilitation hospitals. A convenience sample of nonambulatory individuals with 
      SCI (N = 32) completed an 8-week training protocol consisting of walking training 
      3 times per week utilizing the Indego powered exoskeleton in indoor and outdoor 
      conditions. Participants were also trained in donning/doffing the exoskeleton 
      during each session. Safety measures such as adverse events (AEs) were monitored 
      and reported. Time and independence with donning/doffing the exoskeleton as well 
      as walking outcomes to include the 10-meter walk test (10MWT), 6-minute walk test 
      (6MWT), Timed Up & Go test (TUG), and 600-meter walk test were evaluated from 
      midpoint to final evaluations. Results: All 32 participants completed the 
      training protocol with limited device-related AEs, which resulted in no 
      interruption in training. The majority of participants in this trial were able to 
      don and doff the Indego independently. Final walking speed ranged from 0.19 to 
      0.55 m/s. Final average indoor and outdoor walking speeds among all participants 
      were 0.37 m/s (SD = 0.08, 0.09, respectively), after 8 weeks of training. 
      Significant (p < .05) improvements were noted between midpoint and final gait 
      speeds in both indoor and outdoor conditions. Average walking endurance also 
      improved among participants after training. Conclusion: The Indego was shown to 
      be safe for providing upright mobility to 32 individuals with SCIs who were 
      nonambulatory. Improvements in speed and independence were noted with walking in 
      indoor and outdoor conditions as well as with donning/doffing the exoskeleton.
FAU - Tefertiller, Candy
AU  - Tefertiller C
AD  - Department of Physical Therapy, Craig Hospital, Englewood, Colorado.
FAU - Hays, Kaitlin
AU  - Hays K
AD  - Department of Physical Therapy, Craig Hospital, Englewood, Colorado.
FAU - Jones, Janell
AU  - Jones J
AD  - Department of Physical Therapy, Craig Hospital, Englewood, Colorado.
FAU - Jayaraman, Arun
AU  - Jayaraman A
AD  - Max Nader Center for Rehabilitation Technologies & Outcomes Research, Departments 
      of Physical Medicine & Rehabilitation and Medical Social Sciences, Northwestern 
      University, Shirley Ryan AbilityLab, Chicago, Illinois.
FAU - Hartigan, Clare
AU  - Hartigan C
AD  - Shepherd Center Virginia C. Crawford Research Institute, Shepherd Center, 
      Atlanta, Georgia.
FAU - Bushnik, Tamara
AU  - Bushnik T
AD  - Department of Rehabilitation Medicine Rusk Rehabilitation, NYU Langone Health, 
      New York City, New York.
FAU - Forrest, Gail F
AU  - Forrest GF
AD  - Human Performance and Movement Analysis Research at Kessler Foundation, 
      Department of Physical Medicine and Rehabilitation at Rutgers - New Jersey 
      Medical School, West Orange, New Jersey.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
DEP - 20171120
PL  - United States
TA  - Top Spinal Cord Inj Rehabil
JT  - Topics in spinal cord injury rehabilitation
JID - 9515174
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Equipment Design
MH  - Exercise Therapy/methods
MH  - Exoskeleton Device/*adverse effects
MH  - Female
MH  - *Gait
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Spinal Cord Injuries/*rehabilitation
MH  - Treatment Outcome
MH  - *Walking
MH  - Young Adult
PMC - PMC5791927
OTO - NOTNLM
OT  - ambulation
OT  - exoskeletons
OT  - gait
OT  - paraplegia
OT  - robotic devices
OT  - spinal cord injury
OT  - walking
EDAT- 2018/02/13 06:00
MHDA- 2018/08/28 06:00
PMCR- 2019/01/01
CRDT- 2018/02/14 06:00
PHST- 2018/02/14 06:00 [entrez]
PHST- 2018/02/13 06:00 [pubmed]
PHST- 2018/08/28 06:00 [medline]
PHST- 2019/01/01 00:00 [pmc-release]
AID - 10.1310/sci17-00014 [doi]
PST - ppublish
SO  - Top Spinal Cord Inj Rehabil. 2018 Winter;24(1):78-85. doi: 10.1310/sci17-00014. 
      Epub 2017 Nov 20.