PMID- 29438634 OWN - NLM STAT- MEDLINE DCOM- 20191011 LR - 20200306 IS - 2159-9777 (Electronic) IS - 0279-1072 (Print) IS - 0279-1072 (Linking) VI - 50 IP - 1 DP - 2018 Jan-Mar TI - Regulating Cannabis Manufacturing: Applying Public Health Best Practices from Tobacco Control. PG - 19-32 LID - 10.1080/02791072.2017.1422816 [doi] AB - State legalization and regulation of cannabis, despite continued federal illegality, is a massive shift in regulatory approach. Manufactured cannabis, including concentrates, extracts, edibles, tinctures, topicals and other products, has received less attention than more commonly used dried flower, but represents emerging regulatory challenges due to additives, potency, consumption methods, and abuse and misuse potential. In November 2017, the California Department of Public Health (CDPH) released initial cannabis manufacturing regulations as part of a new state regulatory structure. As the largest U.S. medical cannabis market (and largest legal adult use market in the world beginning in 2018), California's regulatory approach will potentially influence national and global policy. Comparing CDPH's initial regulations to tobacco control best practices reveals that, while the regulations recognize the need to protect public health, prioritizing public health over business interests requires stronger approaches to labeling, packaging, and product formulations. Based on tobacco best practices, we recommend that cannabis regulations incorporate large and proportionately sized informational labels, a prominent universal cannabis symbol, rotating and pictorial health warnings, mandatory plain packaging, a comprehensive ban on characterizing flavors and addictive additives, and strict limits on the potency of inhalable products and those easily confused with non-cannabis products. FAU - Orenstein, Daniel G AU - Orenstein DG AD - a Postdoctoral Fellow, Center for Tobacco Control Research and Education and Philip R. Lee Institute for Health Policy Studies, University of California San Francisco , San Francisco , CA , UA. FAU - Glantz, Stanton A AU - Glantz SA AUID- ORCID: 0000-0003-4620-6672 AD - b Professor of Medicine, Truth Initiative Distingished Professor of Tobacco Control, Center for Tobacco Control Research and Education, Philip R. Lee Institute for Health Policy Studies, and Department of Medicine , University of California San Francisco , San Francisco , CA , USA. LA - eng GR - R01 DA043950/DA/NIDA NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20180213 PL - United States TA - J Psychoactive Drugs JT - Journal of psychoactive drugs JID - 8113536 RN - 0 (Medical Marijuana) SB - IM MH - Adult MH - California MH - Drug Labeling/legislation & jurisprudence MH - Drug Packaging/legislation & jurisprudence MH - Humans MH - Industry/*legislation & jurisprudence MH - *Medical Marijuana MH - Product Labeling/legislation & jurisprudence MH - Product Packaging/legislation & jurisprudence MH - *Public Health MH - Tobacco Industry/*legislation & jurisprudence PMC - PMC5878137 MID - NIHMS938636 OTO - NOTNLM OT - Cannabis OT - marijuana concentrates OT - marijuana edibles OT - marijuana extracts OT - marijuana labeling OT - marijuana legalization EDAT- 2018/02/14 06:00 MHDA- 2019/10/12 06:00 PMCR- 2019/02/13 CRDT- 2018/02/14 06:00 PHST- 2018/02/14 06:00 [pubmed] PHST- 2019/10/12 06:00 [medline] PHST- 2018/02/14 06:00 [entrez] PHST- 2019/02/13 00:00 [pmc-release] AID - 10.1080/02791072.2017.1422816 [doi] PST - ppublish SO - J Psychoactive Drugs. 2018 Jan-Mar;50(1):19-32. doi: 10.1080/02791072.2017.1422816. Epub 2018 Feb 13.