PMID- 29448955
OWN - NLM
STAT- MEDLINE
DCOM- 20180905
LR  - 20181113
IS  - 1297-9716 (Electronic)
IS  - 0928-4249 (Print)
IS  - 0928-4249 (Linking)
VI  - 49
IP  - 1
DP  - 2018 Feb 15
TI  - Analysis of the genetic diversity and mRNA expression level in porcine 
      reproductive and respiratory syndrome virus vaccinated pigs that developed short 
      or long viremias after challenge.
PG  - 19
LID - 10.1186/s13567-018-0514-1 [doi]
LID - 19
AB  - Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the 
      host's cellular and humoral immune response. Immunity against PRRSv is multigenic 
      and vary between individuals. The aim of the present study was to compare several 
      genes that encode for molecules involved in the immune response between two 
      groups of vaccinated pigs that experienced short or long viremic periods after 
      PRRSv challenge. These analyses include the sequencing of four SLA Class I, two 
      Class II allele groups, and CD163, plus the analysis by quantitative realtime 
      qRT-PCR of the constitutive expression of TLR2, TLR3, TLR4, TLR7, TLR8 and TLR9 
      mRNA and other molecules in peripheral blood mononuclear cells.
FAU - Cortey, Marti
AU  - Cortey M
AUID- ORCID: 0000-0003-1126-3423
AD  - Departament de Sanitat i d'Anatomia Animals, Universitat Autonoma de Barcelona, 
      08193, Cerdanyola Del Valles, Spain. marti.cortey@uab.cat.
FAU - Arocena, Gaston
AU  - Arocena G
AD  - Departament de Sanitat i d'Anatomia Animals, Universitat Autonoma de Barcelona, 
      08193, Cerdanyola Del Valles, Spain.
FAU - Ait-Ali, Tahar
AU  - Ait-Ali T
AD  - The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of 
      Edinburgh, Midlothian, EH25 9RG, UK.
FAU - Vidal, Anna
AU  - Vidal A
AD  - Departament de Sanitat i d'Anatomia Animals, Universitat Autonoma de Barcelona, 
      08193, Cerdanyola Del Valles, Spain.
FAU - Li, Yanli
AU  - Li Y
AD  - Departament de Sanitat i d'Anatomia Animals, Universitat Autonoma de Barcelona, 
      08193, Cerdanyola Del Valles, Spain.
FAU - Martin-Valls, Gerard
AU  - Martin-Valls G
AD  - Departament de Sanitat i d'Anatomia Animals, Universitat Autonoma de Barcelona, 
      08193, Cerdanyola Del Valles, Spain.
FAU - Wilson, Alison D
AU  - Wilson AD
AD  - The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of 
      Edinburgh, Midlothian, EH25 9RG, UK.
FAU - Archibald, Allan L
AU  - Archibald AL
AD  - The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of 
      Edinburgh, Midlothian, EH25 9RG, UK.
FAU - Mateu, Enric
AU  - Mateu E
AD  - Departament de Sanitat i d'Anatomia Animals, Universitat Autonoma de Barcelona, 
      08193, Cerdanyola Del Valles, Spain.
AD  - IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la 
      Universitat Autonoma de Barcelona, 08193, Cerdanyola Del Valles, Spain.
FAU - Darwich, Laila
AU  - Darwich L
AD  - Departament de Sanitat i d'Anatomia Animals, Universitat Autonoma de Barcelona, 
      08193, Cerdanyola Del Valles, Spain.
AD  - IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la 
      Universitat Autonoma de Barcelona, 08193, Cerdanyola Del Valles, Spain.
LA  - eng
GR  - BB/J004227/1/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
GR  - BB/P013740/1/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180215
PL  - England
TA  - Vet Res
JT  - Veterinary research
JID - 9309551
RN  - 0 (RNA, Messenger)
RN  - 0 (Viral Vaccines)
SB  - IM
MH  - Animals
MH  - *Gene Expression
MH  - *Genetic Variation
MH  - Immunity, Innate/*genetics
MH  - Porcine Reproductive and Respiratory Syndrome/*immunology
MH  - Porcine respiratory and reproductive syndrome virus/*physiology
MH  - RNA, Messenger/*genetics/metabolism
MH  - Swine
MH  - Viral Vaccines/administration & dosage
MH  - Viremia/*microbiology
PMC - PMC5815215
EDAT- 2018/02/17 06:00
MHDA- 2018/09/06 06:00
PMCR- 2018/02/15
CRDT- 2018/02/17 06:00
PHST- 2017/12/13 00:00 [received]
PHST- 2018/02/08 00:00 [accepted]
PHST- 2018/02/17 06:00 [entrez]
PHST- 2018/02/17 06:00 [pubmed]
PHST- 2018/09/06 06:00 [medline]
PHST- 2018/02/15 00:00 [pmc-release]
AID - 10.1186/s13567-018-0514-1 [pii]
AID - 514 [pii]
AID - 10.1186/s13567-018-0514-1 [doi]
PST - epublish
SO  - Vet Res. 2018 Feb 15;49(1):19. doi: 10.1186/s13567-018-0514-1.