PMID- 29455177
OWN - NLM
STAT- MEDLINE
DCOM- 20180913
LR  - 20231112
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 2018
DP  - 2018 Feb 17
TI  - NMDAR (N-methyl-D-aspartate receptor) encephalitis in a patient with MS (multiple 
      sclerosis): a rare and challenging case.
LID - bcr-2017-222086 [pii]
LID - 10.1136/bcr-2017-222086 [doi]
LID - bcr2017222086
AB  - We present a rare case of N-methyl-D-aspartate receptor (NMDAR) encephalitis in a 
      41-year-old Caucasian woman, who initially presented with prominent 
      neuropsychiatric symptoms on the background of pre-existing multiple sclerosis. 
      Here, the authors navigate the muddy water between neurology and psychiatry, 
      describing the caveats of antibody testing with a misdiagnosed case of acute and 
      transient psychotic episode. NMDAR encephalitis in MS is a rare condition, which 
      can be easily confused with a new onset psychotic episode. This case report can 
      be helpful in recognition and diagnosis of this rare condition. Making the right 
      diagnosis is important since it can prevent an unnecessary radical treatment and 
      long-term neuropsychiatric complications.
CI  - (c) BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 
      2018. All rights reserved. No commercial use is permitted unless otherwise 
      expressly granted.
FAU - Suleman, Sadia
AU  - Suleman S
AD  - General Adult Psychiatry, Mersey Care NHS Foundation Trust, Liverpool.
FAU - Javed, Qaiser
AU  - Javed Q
AD  - Liaison Psychiatry, Aintree University Hospitals NHS Foundation Trust, Liverpool, 
      UK.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20180217
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
RN  - 0 (Antipsychotic Agents)
RN  - 0 (Immunoglobulins, Intravenous)
RN  - 0 (Immunologic Factors)
RN  - 0 (Receptors, N-Methyl-D-Aspartate)
RN  - 4F4X42SYQ6 (Rituximab)
SB  - IM
MH  - Acute Disease
MH  - Adult
MH  - Anti-N-Methyl-D-Aspartate Receptor 
      Encephalitis/complications/*diagnosis/psychology/therapy
MH  - Antipsychotic Agents/therapeutic use
MH  - Delayed Diagnosis
MH  - Female
MH  - Humans
MH  - Immunoglobulins, Intravenous/*therapeutic use
MH  - Immunologic Factors/therapeutic use
MH  - Multiple Sclerosis/complications
MH  - Plasma Exchange
MH  - Psychotic Disorders/*etiology
MH  - Receptors, N-Methyl-D-Aspartate/analysis/*immunology
MH  - Rituximab/therapeutic use
PMC - PMC5836642
OTO - NOTNLM
OT  - delirium
OT  - infection (neurology)
OT  - memory disorders
OT  - multiple sclerosis
OT  - psychotic disorders (incl schizophrenia)
COIS- Competing interests: None declared.
EDAT- 2018/02/20 06:00
MHDA- 2018/09/14 06:00
PMCR- 2020/02/17
CRDT- 2018/02/19 06:00
PHST- 2018/02/19 06:00 [entrez]
PHST- 2018/02/20 06:00 [pubmed]
PHST- 2018/09/14 06:00 [medline]
PHST- 2020/02/17 00:00 [pmc-release]
AID - bcr-2017-222086 [pii]
AID - 10.1136/bcr-2017-222086 [doi]
PST - epublish
SO  - BMJ Case Rep. 2018 Feb 17;2018:bcr2017222086. doi: 10.1136/bcr-2017-222086.