PMID- 29457059 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 2363-9024 (Electronic) IS - 2363-9024 (Linking) VI - 3 IP - 1 DP - 2017 TI - Unexpected bioprosthetic mitral valve thrombus during left ventricular assist device implantation. PG - 15 LID - 10.1186/s40981-017-0086-5 [doi] LID - 15 AB - Acute bioprosthetic valve thrombosis can occur after surgery and sometimes cause hemodynamic instability and cardiogenic shock. Risk factors for bioprosthetic valve thrombosis are hypercoagulability, atrial fibrillation, atrial dilatation, low cardiac function, and lack of anticoagulation therapy. The authors present a case of severe mitral stenosis due to bioprosthetic valve thrombus. The patient was diagnosed with dilated-phase hypertrophic cardiomyopathy and underwent mitral valve replacement. He required venoarterial extracorporeal membrane oxygenation (VA-ECMO) due to extremely low cardiac output and was scheduled for left ventricular assist device (LVAD) implantation. Transesophageal echocardiographic examination before LVAD implantation revealed severe mitral stenosis due to bioprosthetic mitral valve thrombus, which was not detected by transthoracic echocardiography in the intensive care unit and contributed to the low cardiac function. The thrombus was removed through an unscheduled left atriotomy before LVAD implantation. The possibility of bioprosthetic valve thrombosis must be considered when the patient is dependent on VA-ECMO support. Early transesophageal echocardiographic examination of the bioprosthetic valve may be helpful and contribute to surgical decision-making. FAU - Imada, Tatsuyuki AU - Imada T AD - Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871 Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b FAU - Shibata, Sho Carl AU - Shibata SC AD - Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871 Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b FAU - Okitsu, Kenta AU - Okitsu K AD - Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871 Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b FAU - Fujino, Yuji AU - Fujino Y AD - Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871 Japan. ISNI: 0000 0004 0373 3971. GRID: grid.136593.b LA - eng PT - Journal Article DEP - 20170417 PL - Germany TA - JA Clin Rep JT - JA clinical reports JID - 101682121 PMC - PMC5804597 OTO - NOTNLM OT - Bioprosthetic valve thrombosis OT - Mitral stenosis OT - Mitral valve replacement COIS- The authors declare that they have no competing interests. EDAT- 2018/02/20 06:00 MHDA- 2018/02/20 06:01 PMCR- 2017/04/17 CRDT- 2018/02/20 06:00 PHST- 2017/01/12 00:00 [received] PHST- 2017/04/08 00:00 [accepted] PHST- 2018/02/20 06:00 [entrez] PHST- 2018/02/20 06:00 [pubmed] PHST- 2018/02/20 06:01 [medline] PHST- 2017/04/17 00:00 [pmc-release] AID - 86 [pii] AID - 10.1186/s40981-017-0086-5 [doi] PST - ppublish SO - JA Clin Rep. 2017;3(1):15. doi: 10.1186/s40981-017-0086-5. Epub 2017 Apr 17.