PMID- 29460070
OWN - NLM
STAT- MEDLINE
DCOM- 20181024
LR  - 20220408
IS  - 1432-1084 (Electronic)
IS  - 0938-7994 (Linking)
VI  - 28
IP  - 8
DP  - 2018 Aug
TI  - Comparison of image quality and radiation dose between split-filter dual-energy 
      images and single-energy images in single-source abdominal CT.
PG  - 3405-3412
LID - 10.1007/s00330-018-5338-x [doi]
AB  - OBJECTIVES: To compare image quality and radiation dose of abdominal split-filter 
      dual-energy CT (SF-DECT) combined with monoenergetic imaging to single-energy CT 
      (SECT) with automatic tube voltage selection (ATVS). METHODS: Two-hundred 
      single-source abdominal CT scans were performed as SECT with ATVS (n = 100) and 
      SF-DECT (n = 100). SF-DECT scans were reconstructed and subdivided into composed 
      images (SF-CI) and monoenergetic images at 55 keV (SF-MI). Objective and 
      subjective image quality were compared among single-energy images (SEI), SF-CI 
      and SF-MI. CNR and FOM were separately calculated for the liver (e.g. CNR(liv)) 
      and the portal vein (CNR(pv)). Radiation dose was compared using size-specific 
      dose estimate (SSDE). Results of the three groups were compared using 
      non-parametric tests. RESULTS: Image noise of SF-CI was 18% lower compared to SEI 
      and 48% lower compared to SF-MI (p < 0.001). Composed images yielded higher 
      CNR(liv) over single-energy images (23.4 vs. 20.9; p < 0.001), whereas CNR(pv) 
      was significantly lower (3.5 vs. 5.2; p < 0.001). Monoenergetic images overcame 
      this inferiority in CNR(pv) and achieved similar results compared to 
      single-energy images (5.1 vs. 5.2; p > 0.628). Subjective sharpness was equal 
      between single-energy and monoenergetic images and diagnostic confidence was 
      equal between single-energy and composed images. FOM(liv) was highest for SF-CI. 
      FOM(pv) was equal for SEI and SF-MI (p = 0.78). SSDE was significant lower for 
      SF-DECT compared to SECT (p < 0.022). CONCLUSIONS: The combined use of 
      split-filter dual-energy CT images provides comparable objective and subjective 
      image quality at lower radiation dose compared to single-energy CT with ATVS. KEY 
      POINTS: * Split-filter dual-energy results in 18% lower noise compared to 
      single-energy with ATVS. * Split-filter dual-energy results in 11% lower SSDE 
      compared to single-energy with ATVS. * Spectral shaping of split-filter 
      dual-energy leads to an increased dose-efficiency.
FAU - Euler, Andre
AU  - Euler A
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University 
      of Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
AD  - Department of Radiology, Duke University Medical Center, Durham, NC, USA.
FAU - Obmann, Markus M
AU  - Obmann MM
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University 
      of Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
FAU - Szucs-Farkas, Zsolt
AU  - Szucs-Farkas Z
AD  - Institute of Radiology, Hospital Centre of Biel, Biel, Switzerland.
FAU - Mileto, Achille
AU  - Mileto A
AD  - Department of Radiology, University of Washington School of Medicine, Seattle, 
      WA, USA.
FAU - Zaehringer, Caroline
AU  - Zaehringer C
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University 
      of Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
FAU - Falkowski, Anna L
AU  - Falkowski AL
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University 
      of Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
FAU - Winkel, David J
AU  - Winkel DJ
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University 
      of Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
FAU - Marin, Daniele
AU  - Marin D
AD  - Department of Radiology, Duke University Medical Center, Durham, NC, USA.
FAU - Stieltjes, Bram
AU  - Stieltjes B
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University 
      of Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
FAU - Krauss, Bernhard
AU  - Krauss B
AD  - Siemens Medical Solutions, Erlangen, Germany.
FAU - Schindera, Sebastian T
AU  - Schindera ST
AD  - Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University 
      of Basel, Petersgraben 4, CH-4031, Basel, Switzerland. sschindera@aol.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20180219
PL  - Germany
TA  - Eur Radiol
JT  - European radiology
JID - 9114774
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Male
MH  - Middle Aged
MH  - *Radiation Dosage
MH  - Radiography, Abdominal/*methods
MH  - Radiography, Dual-Energy Scanned Projection/methods
MH  - Retrospective Studies
MH  - Signal-To-Noise Ratio
MH  - Tomography, X-Ray Computed/*methods
MH  - Young Adult
OTO - NOTNLM
OT  - Automatic tube voltage selection
OT  - Single-source dual-energy CT
OT  - Spectral shaping
OT  - Split-filter dual-energy CT
OT  - Virtual monoenergetic imaging
EDAT- 2018/02/21 06:00
MHDA- 2018/10/26 06:00
CRDT- 2018/02/21 06:00
PHST- 2017/02/16 00:00 [received]
PHST- 2018/01/17 00:00 [accepted]
PHST- 2018/01/09 00:00 [revised]
PHST- 2018/02/21 06:00 [pubmed]
PHST- 2018/10/26 06:00 [medline]
PHST- 2018/02/21 06:00 [entrez]
AID - 10.1007/s00330-018-5338-x [pii]
AID - 10.1007/s00330-018-5338-x [doi]
PST - ppublish
SO  - Eur Radiol. 2018 Aug;28(8):3405-3412. doi: 10.1007/s00330-018-5338-x. Epub 2018 
      Feb 19.