PMID- 29465549 OWN - NLM STAT- MEDLINE DCOM- 20180302 LR - 20240316 IS - 1536-5964 (Electronic) IS - 0025-7974 (Print) IS - 0025-7974 (Linking) VI - 97 IP - 8 DP - 2018 Feb TI - Cardiorespiratory parameters and glycated hemoglobin of patients with type 2 diabetes after a rehabilitation program. PG - e9321 LID - 10.1097/MD.0000000000009321 [doi] LID - e9321 AB - INTRODUCTION: Cardiovascular autonomic dysfunction reflex of the pathophysiology of diabetes mellitus (DM) favors an increase in morbidity and mortality related to cardiovascular events, and for this reason has been one of the most studied clinical entities. METHOD: An experimental study of a randomized clinical trial type was therefore proposed to analyze the hemodynamic and glycemic response after the practice of a rehabilitation program in patients with type 2 diabetes mellitus (T2DM). In this clinical trial the patients will initially be submitted to an evaluation protocol that consists of assessing blood pressure, heart rate, Borg scale, respiratory rate, oxygen saturation, distance traveled through the 6-minute walk test, quality of life questionnaire, Pittsburgh sleep quality questionnaire, and still glycated hemoglobin and heart rate variability through the cardiofrequency meter. After careful evaluation of the patients, they will be submitted to a metabolic rehabilitation program composed of aerobic and resisted exercises, performed for 12 weeks, in 3 weekly meetings of 60 minutes each. With such evaluations, it will be possible to construct with evidence that it is possible to work safer metabolic rehabilitation programs in patients with T2DM or other diseases that generate cardiovascular risks, guaranteeing them an improvement in cardiorespiratory fitness, hemodynamic and glycemic variables, allowing improvement of the quality of life. ETHICS AND DISSEMINATION: The protocol is approved by the host institution's ethics committee under the number 1.616.721. Results will be disseminated via peer-reviewed journal articles and conferences. This clinical trial is registered at ClinicalTrials.gov identifier: NCT3094767. FAU - Marques, Natalia da Silva Freitas AU - Marques NDSF AD - Laboratory of Study Design and Scientific Writing of the Faculty of Medicine of ABC, Prince of Wales, Santo Andre/SP-CEP, Brazil Research Laboratory of UNINORTE-Baron College of Rio Branco, Alameda Hungary, Rio Branco/AC-CEP, Brazil. FAU - Abreu, Luiz Carlos de AU - Abreu LC FAU - Santos, Barbara Vieira Dos AU - Santos BVD FAU - Neto, Candido Ferreira Rodrigues AU - Neto CFR FAU - Silva, Jose Rener Cordeiro da AU - Silva JRCD FAU - Braga, Karine Ketlem de Souza AU - Braga KKS FAU - Uchoa, Kariny da Silva AU - Uchoa KDS FAU - Moraes, Laila Maria Silva AU - Moraes LMS FAU - Ferreira, Leillane Cristina de Paiva AU - Ferreira LCP FAU - Ribeiro, Natanael Guimaraes AU - Ribeiro NG FAU - Santos, Savio Lima Dos AU - Santos SLD FAU - Silva, Tayna Almeida da AU - Silva TAD FAU - Andrade, Paulo Evaristo de AU - Andrade PE FAU - Raimundo, Rodrigo Daminello AU - Raimundo RD LA - eng SI - ClinicalTrials.gov/NCT03094767 SI - ClinicalTrials.gov/NCT03094767 PT - Journal Article PT - Randomized Controlled Trial PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R RN - 0 (Blood Glucose) RN - 0 (Glycated Hemoglobin A) RN - 0 (hemoglobin A1c protein, human) SB - IM MH - Adult MH - Blood Glucose/analysis MH - Blood Pressure MH - Clinical Protocols MH - *Diabetes Mellitus, Type 2/blood/physiopathology/rehabilitation MH - Exercise/*physiology MH - Female MH - Glycated Hemoglobin/*analysis MH - Heart Rate MH - Humans MH - Male MH - Oxygen Consumption MH - Quality of Life MH - Resistance Training/*methods MH - Sleep MH - Surveys and Questionnaires MH - Treatment Outcome MH - Walk Test PMC - PMC5841997 COIS- The authors have no conflicts of interest to disclose. EDAT- 2018/02/22 06:00 MHDA- 2018/03/03 06:00 PMCR- 2018/02/23 CRDT- 2018/02/22 06:00 PHST- 2018/02/22 06:00 [entrez] PHST- 2018/02/22 06:00 [pubmed] PHST- 2018/03/03 06:00 [medline] PHST- 2018/02/23 00:00 [pmc-release] AID - 00005792-201802230-00014 [pii] AID - MD-D-17-05854 [pii] AID - 10.1097/MD.0000000000009321 [doi] PST - ppublish SO - Medicine (Baltimore). 2018 Feb;97(8):e9321. doi: 10.1097/MD.0000000000009321.