PMID- 29474205
OWN - NLM
STAT- MEDLINE
DCOM- 20180925
LR  - 20180925
IS  - 1473-5733 (Electronic)
IS  - 0957-5235 (Linking)
VI  - 29
IP  - 3
DP  - 2018 Apr
TI  - Perioperative management of a patient with Glanzmann thrombasthenia undergoing a 
      coronary artery bypass graft surgery: a case report.
PG  - 327-329
LID - 10.1097/MBC.0000000000000719 [doi]
AB  - : We report herein the successful perioperative management of a 57-year-old man 
      with a type I Glanzmann thrombasthenia undergoing coronary artery bypass graft 
      surgery and right carotid endarterectomy. The patient suffered from several 
      lesions in the three major coronary arteries and in the right carotid 
      necessitating surgery. Prophylactic human leukocyte antigen (HLA)-matched 
      platelets transfusions were continuous administrated before, and through the 
      immediate perioperative period. Posttransfusion platelet recovery was monitored 
      using flow cytometry to determine the percentage of circulating platelet 
      expressing CD61 (beta3). No bleeding complications occurred during and following the 
      procedure. The patient did not develop HLA antibodies or alphaIIbbeta3 antibodies. 
      Thrombophilia screening revealed a heterozygous G20210A prothrombin gene 
      mutation. The patient also suffered from an atrial fibrillation, necessitating 
      anticoagulation therapy. During the hospital stay, a treatment with vitamin K 
      antagonists for stroke prevention was initiated. The patient was discharged 8 
      days following surgery, and no further complications occurred during the 6 months 
      follow-up.
FAU - Kurdi, Mohamad
AU  - Kurdi M
AD  - Department of Biological Hematology.
FAU - Frere, Corinne
AU  - Frere C
AD  - Department of Biological Hematology.
FAU - Amour, Julien
AU  - Amour J
AD  - Department of Anesthesia, Assistance Publique-Hopitaux de Paris, Pitie 
      Salpetriere Hospital.
FAU - Brumpt, Caren
AU  - Brumpt C
AD  - Department of Biological Hematology, Assistance Publique-Hopitaux de Paris, 
      Lariboisiere Hospital.
FAU - Delort, Josee
AU  - Delort J
AD  - Etablissement Francais du Sang (EFS), GH La Pitie Salpetriere.
FAU - Lebreton, Guillaume
AU  - Lebreton G
AD  - Department of Cardiac Surgery, Assistance Publique-Hopitaux de Paris, Pitie 
      Salpetriere Hospital.
FAU - Croisille, Laure
AU  - Croisille L
AD  - Etablissement Francais du Sang (EFS), CHU Henri Mondor.
FAU - d'Oiron, Roseline
AU  - d'Oiron R
AD  - Assistance publique-Hopitaux de Paris, Hopitaux Universitaires Paris-Sud, Hopital 
      Bicetre, Centre de Traitement de l'Hemophilie et des Maladies Hemorragiques 
      Constitutionnelles, Le Kremlin Bicetre, France.
FAU - Martin-Toutain, Isabelle
AU  - Martin-Toutain I
AD  - Department of Biological Hematology.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Blood Coagul Fibrinolysis
JT  - Blood coagulation & fibrinolysis : an international journal in haemostasis and 
      thrombosis
JID - 9102551
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Atrial Fibrillation/drug therapy
MH  - Carotid Arteries/*surgery
MH  - *Coronary Artery Bypass
MH  - Coronary Vessels/*surgery
MH  - HLA Antigens/immunology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Perioperative Period
MH  - Platelet Transfusion
MH  - Stroke/prevention & control
MH  - Thrombasthenia/*therapy
MH  - Thrombophilia/genetics
MH  - Treatment Outcome
EDAT- 2018/02/24 06:00
MHDA- 2018/09/27 06:00
CRDT- 2018/02/24 06:00
PHST- 2018/02/24 06:00 [pubmed]
PHST- 2018/09/27 06:00 [medline]
PHST- 2018/02/24 06:00 [entrez]
AID - 10.1097/MBC.0000000000000719 [doi]
PST - ppublish
SO  - Blood Coagul Fibrinolysis. 2018 Apr;29(3):327-329. doi: 
      10.1097/MBC.0000000000000719.