PMID- 29476432
OWN - NLM
STAT- MEDLINE
DCOM- 20181026
LR  - 20181202
IS  - 1573-2584 (Electronic)
IS  - 0301-1623 (Linking)
VI  - 50
IP  - 5
DP  - 2018 May
TI  - Cigarette smoking and risk of albuminuria in patients with type 2 diabetes: a 
      systematic review and meta-analysis of observational studies.
PG  - 911-922
LID - 10.1007/s11255-018-1825-x [doi]
AB  - BACKGROUND: The aim of this study was to assess the effects of smoking on 
      albuminuria risk in adults with type 2 diabetes mellitus (T2DM). METHODS: A 
      literature search was conducted using MEDLINE, EMBASE, and China National 
      Knowledge Infrastructure from the established date to October 2017. Summary 
      relative risks (SRR) and 95% confidence intervals (CI) were computed utilizing a 
      random effect inverse variance method. RESULTS: This meta-analysis included a 
      total of 19 relevant observational studies (four prospective cohort, seven 
      case-control, and eight cross-sectional studies), reporting 105,031 participants 
      and 23,366 albuminuria events. Compared with never-smokers with T2DM, the SRRs of 
      albuminuria were 1.43 (95% CIs 1.27-1.61) for ever-smokers, 2.61 (95% CIs 
      1.86-3.64) for current smokers, and 1.86 (95% CIs 1.37-2.52) for former smokers. 
      Considerable heterogeneity was observed among these studies, and study design was 
      a significant modifier for this association. There were significantly elevated 
      risk associations for microalbuminuria (SRRs = 1.24, 95% CIs 1.05-1.46) and for 
      macroalbuminuria (SRRs = 1.65, 95% CIs 1.03-2.66), respectively. CONCLUSIONS: Our 
      systematic review and meta-analysis indicates that cigarette smoking might be a 
      potential factor for the development of albuminuria in adults with T2DM. Future 
      studies are required to investigate the association between smoking cessation and 
      intensity and incident albuminuria in adults with T2DM.
FAU - Xu, Haili
AU  - Xu H
AD  - Department of Nursing, The First Affiliated Hospital, Zhengzhou University, 
      Zhengzhou, Henan Province, People's Republic of China.
FAU - Suo, Jinliu
AU  - Suo J
AD  - Department of Urology Surgery, The First Affiliated Hospital, Zhengzhou 
      University, 1 Jianshe Dong Road, Zhengzhou, 450052, Henan Province, People's 
      Republic of China.
FAU - Lian, Jing
AU  - Lian J
AUID- ORCID: 0000-0001-5692-6388
AD  - Department of Urology Surgery, The First Affiliated Hospital, Zhengzhou 
      University, 1 Jianshe Dong Road, Zhengzhou, 450052, Henan Province, People's 
      Republic of China. jinglian321@126.com.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20180223
PL  - Netherlands
TA  - Int Urol Nephrol
JT  - International urology and nephrology
JID - 0262521
SB  - IM
MH  - Albuminuria/*epidemiology
MH  - Cigarette Smoking/*epidemiology
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Humans
MH  - Observational Studies as Topic
MH  - Risk Factors
OTO - NOTNLM
OT  - Albuminuria
OT  - Cigarette smoking
OT  - Meta-analysis
OT  - Type 2 diabetes mellitus
EDAT- 2018/02/25 06:00
MHDA- 2018/10/27 06:00
CRDT- 2018/02/25 06:00
PHST- 2017/12/25 00:00 [received]
PHST- 2018/02/13 00:00 [accepted]
PHST- 2018/02/25 06:00 [pubmed]
PHST- 2018/10/27 06:00 [medline]
PHST- 2018/02/25 06:00 [entrez]
AID - 10.1007/s11255-018-1825-x [pii]
AID - 10.1007/s11255-018-1825-x [doi]
PST - ppublish
SO  - Int Urol Nephrol. 2018 May;50(5):911-922. doi: 10.1007/s11255-018-1825-x. Epub 
      2018 Feb 23.